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Murcko scaffold

Ring system with 2 rings and 18 atoms

119 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
18
Chemicals
119
With full pages
8
Scaffold SMILES

O=C(CCSc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CCSc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 119 chemicals

Methyl 2-({3-[(4-chlorophenyl)sulfanyl]propanoyl}amino)benzoate chemical structure, C17H16ClNO3S, CAS 335416-17-6
Methyl 2-({3-[(4-chlorophenyl)sulfanyl]propanoyl}amino)benzoate
CAS 335416-17-6C17H16ClNO3S
N-(4-Chloro-2-methylphenyl)-3-(4-chlorophenyl)sulfanylpropanamide chemical structure, C16H15Cl2NOS, CAS 426229-40-5
N-(4-Chloro-2-methylphenyl)-3-(4-chlorophenyl)sulfanylpropanamide
CAS 426229-40-5C16H15Cl2NOS
3-(4-Methylphenyl)sulfanyl-N-[2-(trifluoromethyl)phenyl]propanamide chemical structure, C17H16F3NOS, CAS 694487-37-1
3-(4-Methylphenyl)sulfanyl-N-[2-(trifluoromethyl)phenyl]propanamide
CAS 694487-37-1C17H16F3NOS
3-(4-Chlorophenyl)sulfanyl-N-(4-methylphenyl)propanamide chemical structure, C16H16ClNOS, CAS 425628-25-7
3-(4-Chlorophenyl)sulfanyl-N-(4-methylphenyl)propanamide
CAS 425628-25-7C16H16ClNOS
3-(4-Chlorophenyl)sulfanyl-N-[4-(cyanomethyl)phenyl]propanamide chemical structure, C17H15ClN2OS, CAS 862676-05-9
3-(4-Chlorophenyl)sulfanyl-N-[4-(cyanomethyl)phenyl]propanamide
CAS 862676-05-9C17H15ClN2OS
N-(3-Chloro-4-methylphenyl)-3-(4-chlorophenyl)sulfanylpropanamide chemical structure, C16H15Cl2NOS, CAS 428458-05-3
N-(3-Chloro-4-methylphenyl)-3-(4-chlorophenyl)sulfanylpropanamide
CAS 428458-05-3C16H15Cl2NOS
N-(4-Chloro-2-methylphenyl)-3-(phenylsulfanyl)propanamide chemical structure, C16H16ClNOS, CAS 425665-66-3
N-(4-Chloro-2-methylphenyl)-3-(phenylsulfanyl)propanamide
CAS 425665-66-3C16H16ClNOS
N-(5-Chloro-2-methylphenyl)-3-phenylsulfanylpropanamide chemical structure, C16H16ClNOS, CAS 425680-09-7
N-(5-Chloro-2-methylphenyl)-3-phenylsulfanylpropanamide
CAS 425680-09-7C16H16ClNOS
3-[(4-Chlorophenyl)sulfanyl]-N-(4-fluorophenyl)propanamide chemical structure, C15H13ClFNOS, CAS 426227-43-2
3-[(4-Chlorophenyl)sulfanyl]-N-(4-fluorophenyl)propanamide
CAS 426227-43-2C15H13ClFNOS
N-(2-Methoxyphenyl)-3-(4-methylphenyl)sulfanylpropanamide chemical structure, C17H19NO2S, CAS 565172-81-8
N-(2-Methoxyphenyl)-3-(4-methylphenyl)sulfanylpropanamide
CAS 565172-81-8C17H19NO2S
N-(3-Methylphenyl)-3-[(4-methylphenyl)sulfanyl]propanamide chemical structure, C17H19NOS, CAS 693797-00-1
N-(3-Methylphenyl)-3-[(4-methylphenyl)sulfanyl]propanamide
CAS 693797-00-1C17H19NOS
3-(4-Methylphenyl)sulfanyl-N-(4-propan-2-ylphenyl)propanamide chemical structure, C19H23NOS, CAS 693797-23-8
3-(4-Methylphenyl)sulfanyl-N-(4-propan-2-ylphenyl)propanamide
CAS 693797-23-8C19H23NOS
N-(2,4-Dimethylphenyl)-3-(4-methylphenyl)sulfanylpropanamide chemical structure, C18H21NOS, CAS 693797-29-4
N-(2,4-Dimethylphenyl)-3-(4-methylphenyl)sulfanylpropanamide
CAS 693797-29-4C18H21NOS
Methyl 4-({3-[(4-methylphenyl)sulfanyl]propanoyl}amino)benzoate chemical structure, C18H19NO3S, CAS 693798-39-9
Methyl 4-({3-[(4-methylphenyl)sulfanyl]propanoyl}amino)benzoate
CAS 693798-39-9C18H19NO3S
Methyl 2-({3-[(4-methylphenyl)sulfanyl]propanoyl}amino)benzoate chemical structure, C18H19NO3S, CAS 664319-64-6
Methyl 2-({3-[(4-methylphenyl)sulfanyl]propanoyl}amino)benzoate
CAS 664319-64-6C18H19NO3S
N-(3,4-Dimethylphenyl)-3-(4-methylphenyl)sulfanylpropanamide chemical structure, C18H21NOS, CAS 693809-17-5
N-(3,4-Dimethylphenyl)-3-(4-methylphenyl)sulfanylpropanamide
CAS 693809-17-5C18H21NOS
N-(2-Methylphenyl)-3-(4-methylphenyl)sulfanylpropanamide chemical structure, C17H19NOS, CAS 693813-27-3
N-(2-Methylphenyl)-3-(4-methylphenyl)sulfanylpropanamide
CAS 693813-27-3C17H19NOS
N-(2,3-Dimethylphenyl)-3-(phenylthio)propanamide chemical structure, C17H19NOS, CAS 392327-02-5
N-(2,3-Dimethylphenyl)-3-(phenylthio)propanamide
CAS 392327-02-5C17H19NOS
3-[(4-Chlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)propanamide chemical structure, C15H12ClF2NOS, CAS 380321-84-6
3-[(4-Chlorophenyl)sulfanyl]-N-(2,4-difluorophenyl)propanamide
CAS 380321-84-6C15H12ClF2NOS
N-(3-Chloro-4-fluorophenyl)-3-phenylsulfanylpropanamide chemical structure, C15H13ClFNOS, CAS 527702-82-5
N-(3-Chloro-4-fluorophenyl)-3-phenylsulfanylpropanamide
CAS 527702-82-5C15H13ClFNOS
N-(3-Acetylphenyl)-3-[(4-chlorophenyl)sulfanyl]propanamide chemical structure, C17H16ClNO2S, CAS 533921-47-0
N-(3-Acetylphenyl)-3-[(4-chlorophenyl)sulfanyl]propanamide
CAS 533921-47-0C17H16ClNO2S
N-(2-Ethylphenyl)-3-[(4-methylphenyl)sulfanyl]propanamide chemical structure, C18H21NOS, CAS 664319-00-0
N-(2-Ethylphenyl)-3-[(4-methylphenyl)sulfanyl]propanamide
CAS 664319-00-0C18H21NOS
N-[4-(Cyanomethyl)phenyl]-3-(4-methylphenyl)sulfanylpropanamide chemical structure, C18H18N2OS, CAS 643005-59-8
N-[4-(Cyanomethyl)phenyl]-3-(4-methylphenyl)sulfanylpropanamide
CAS 643005-59-8C18H18N2OS
N-(3-Acetylphenyl)-3-(p-tolylthio)propanamide chemical structure, C18H19NO2S, CAS 640718-01-0
N-(3-Acetylphenyl)-3-(p-tolylthio)propanamide
CAS 640718-01-0C18H19NO2S