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Murcko scaffold

Ring system with 2 rings and 12 atoms

103 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
103
With full pages
4
Scaffold SMILES

c1ccc(Sc2cnc[nH]2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Sc2cnc[nH]2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 103 chemicals

Imidazole, 5-(O-aminophenylthio)-1-methyl-4-nitro- chemical structure, C10H10N4O2S, CAS 53900-32-6
Imidazole, 5-(O-aminophenylthio)-1-methyl-4-nitro-
CAS 53900-32-6C10H10N4O2S
1-Methyl-4-nitro-5-(phenylsulfanyl)-1H-imidazole chemical structure, C10H9N3O2S, CAS 80812-44-8
1-Methyl-4-nitro-5-(phenylsulfanyl)-1H-imidazole
CAS 80812-44-8C10H9N3O2S
5-(3,5-Dichlorophenylthio)-4-isopropyl-1,2-dimethyl-1H-imidazole chemical structure, C14H16Cl2N2S, CAS 178978-90-0
5-(3,5-Dichlorophenylthio)-4-isopropyl-1,2-dimethyl-1H-imidazole
CAS 178978-90-0C14H16Cl2N2S
1H-Imidazole, 5-((3-chlorophenyl)thio)-1,2-dimethyl-4-(1-methylethyl)- chemical structure, C14H17ClN2S, CAS 178978-92-2
1H-Imidazole, 5-((3-chlorophenyl)thio)-1,2-dimethyl-4-(1-methylethyl)-
CAS 178978-92-2C14H17ClN2S
5-(3,5-Dimethylphenylthio)-4-ethyl-1,2-dimethyl-1H-imidazole chemical structure, C15H20N2S, CAS 178978-94-4
5-(3,5-Dimethylphenylthio)-4-ethyl-1,2-dimethyl-1H-imidazole
CAS 178978-94-4C15H20N2S
5-(3,5-Dimethylphenylthio)-4-isopropyl-1-methyl-1H-imidazole-2-carbaldehyde chemical structure, C16H20N2OS, CAS 178978-95-5
5-(3,5-Dimethylphenylthio)-4-isopropyl-1-methyl-1H-imidazole-2-carbaldehyde
CAS 178978-95-5C16H20N2OS
5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole-2-carbaldehyde chemical structure, C14H14Cl2N2OS, CAS 178978-96-6
5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazole-2-carbaldehyde
CAS 178978-96-6C14H14Cl2N2OS
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol chemical structure, C14H16Cl2N2OS, CAS 178978-97-7
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol
CAS 178978-97-7C14H16Cl2N2OS
1H-Imidazole-2-methanol, 5-((3,5-dimethylphenyl)thio)-1-methyl-4-(1-methylethyl)- chemical structure, C16H22N2OS, CAS 178978-98-8
1H-Imidazole-2-methanol, 5-((3,5-dimethylphenyl)thio)-1-methyl-4-(1-methylethyl)-
CAS 178978-98-8C16H22N2OS
(5-(3-Chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol chemical structure, C14H17ClN2OS, CAS 178979-02-7
(5-(3-Chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol
CAS 178979-02-7C14H17ClN2OS
(4-Isopropyl-1-methyl-5-(3-nitrophenylthio)-1H-imidazol-2-yl)methanol chemical structure, C14H17N3O3S, CAS 178979-03-8
(4-Isopropyl-1-methyl-5-(3-nitrophenylthio)-1H-imidazol-2-yl)methanol
CAS 178979-03-8C14H17N3O3S
(1-Allyl-5-(3-chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol chemical structure, C16H19ClN2OS, CAS 178979-06-1
(1-Allyl-5-(3-chlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol
CAS 178979-06-1C16H19ClN2OS
(5-(3,5-Dichlorophenylthio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl)methanol chemical structure, C25H38Cl2N2OS, CAS 178979-07-2
(5-(3,5-Dichlorophenylthio)-1-dodecyl-4-isopropyl-1H-imidazol-2-yl)methanol
CAS 178979-07-2C25H38Cl2N2OS
(1-Allyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol chemical structure, C16H18Cl2N2OS, CAS 178979-08-3
(1-Allyl-5-(3,5-dichlorophenylthio)-4-isopropyl-1-methyl-1H-imidazol-2-yl)methanol
CAS 178979-08-3C16H18Cl2N2OS
(1-Allyl-4-isopropyl-5-(3-nitrophenylthio)-1-methyl-1H-imidazol-2-yl)methanol chemical structure, C16H19N3O3S, CAS 178979-11-8
(1-Allyl-4-isopropyl-5-(3-nitrophenylthio)-1-methyl-1H-imidazol-2-yl)methanol
CAS 178979-11-8C16H19N3O3S
(1-Ethyl-4-isopropyl-5-(3-nitrophenylthio)-1H-imidazol-2-yl)methanol chemical structure, C15H19N3O3S, CAS 178979-12-9
(1-Ethyl-4-isopropyl-5-(3-nitrophenylthio)-1H-imidazol-2-yl)methanol
CAS 178979-12-9C15H19N3O3S
(4-Isopropyl-5-(3-nitrophenylthio)-1-n-propyl-1H-imidazol-2-yl)methanol chemical structure, C16H21N3O3S, CAS 178979-13-0
(4-Isopropyl-5-(3-nitrophenylthio)-1-n-propyl-1H-imidazol-2-yl)methanol
CAS 178979-13-0C16H21N3O3S
(5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol chemical structure, C15H18Cl2N2OS, CAS 178979-14-1
(5-(3,5-Dichlorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol
CAS 178979-14-1C15H18Cl2N2OS
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-n-propyl-1H-imidazol-2-yl)methanol chemical structure, C16H20Cl2N2OS, CAS 178979-15-2
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-n-propyl-1H-imidazol-2-yl)methanol
CAS 178979-15-2C16H20Cl2N2OS
(5-(3,5-Dichlorophenylthio)-1,4-diisopropyl-1H-imidazol-2-yl)methanol chemical structure, C16H20Cl2N2OS, CAS 178979-16-3
(5-(3,5-Dichlorophenylthio)-1,4-diisopropyl-1H-imidazol-2-yl)methanol
CAS 178979-16-3C16H20Cl2N2OS
(1-(2-Hydroxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl)methanol chemical structure, C16H20Cl2N2O2S, CAS 178979-22-1
(1-(2-Hydroxypropyl)-5-(3,5-dichlorophenylthio)-4-isopropyl-1H-imidazol-2-yl)methanol
CAS 178979-22-1C16H20Cl2N2O2S
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazol-2-yl)methanol chemical structure, C15H15Cl2F3N2OS, CAS 178979-23-2
(5-(3,5-Dichlorophenylthio)-4-isopropyl-1-(2,2,2-trifluoroethyl)-1H-imidazol-2-yl)methanol
CAS 178979-23-2C15H15Cl2F3N2OS
(5-(3,5-Dichlorophenylthio)-1-fluoromethyl-4-isopropyl-1H-imidazol-2-yl)methanol chemical structure, C14H15Cl2FN2OS, CAS 178979-24-3
(5-(3,5-Dichlorophenylthio)-1-fluoromethyl-4-isopropyl-1H-imidazol-2-yl)methanol
CAS 178979-24-3C14H15Cl2FN2OS
(5-(3,5-Difluorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol chemical structure, C15H18F2N2OS, CAS 178979-26-5
(5-(3,5-Difluorophenylthio)-1-ethyl-4-isopropyl-1H-imidazol-2-yl)methanol
CAS 178979-26-5C15H18F2N2OS