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Murcko scaffold

1,2-Benzoisothiazoline 1,1-dioxide scaffold

72 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
72
With full pages
8
Scaffold SMILES

O=S1(=O)NCc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2-Benzoisothiazoline 1,1-dioxide page
Murcko scaffold O=S1(=O)NCc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

1,2-Benzoisothiazoline 1,1-dioxide chemical structure, C7H7NO2S, CAS 936-16-3
1,2-Benzoisothiazoline 1,1-dioxide
CAS 936-16-3C7H7NO2S
1,2-Benzisothiazole-3-acetic acid, 2,3-dihydro-, 1-methylethyl ester,1,1-dioxide chemical structure, C12H15NO4S, CAS 23274-76-2
1,2-Benzisothiazole-3-acetic acid, 2,3-dihydro-, 1-methylethyl ester,1,1-dioxide
CAS 23274-76-2C12H15NO4S
1,2-Benzisothiazoline, 5-chloro-, 1,1-dioxide chemical structure, C7H6ClNO2S, CAS 2515-75-5
1,2-Benzisothiazoline, 5-chloro-, 1,1-dioxide
CAS 2515-75-5C7H6ClNO2S
Butan-2-yl (1,1-dioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-3-yl)acetate chemical structure, C13H17NO4S, CAS 21416-91-1
Butan-2-yl (1,1-dioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-3-yl)acetate
CAS 21416-91-1C13H17NO4S
Methyl (1,1-dioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-3-yl)acetate chemical structure, C10H11NO4S, CAS 21416-93-3
Methyl (1,1-dioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-3-yl)acetate
CAS 21416-93-3C10H11NO4S
1,2-Benzisothiazoline-3-acetic acid, butyl ester, 1,1-dioxide chemical structure, C13H17NO4S, CAS 23274-75-1
1,2-Benzisothiazoline-3-acetic acid, butyl ester, 1,1-dioxide
CAS 23274-75-1C13H17NO4S
1,2-Benzisothiazoline-3-acetic acid, propyl ester, 1,1-dioxide chemical structure, C12H15NO4S, CAS 23274-77-3
1,2-Benzisothiazoline-3-acetic acid, propyl ester, 1,1-dioxide
CAS 23274-77-3C12H15NO4S
1,2-Benzisothiazoline-3-acetic acid, ethyl ester, 1,1-dioxide chemical structure, C11H13NO4S, CAS 23274-78-4
1,2-Benzisothiazoline-3-acetic acid, ethyl ester, 1,1-dioxide
CAS 23274-78-4C11H13NO4S
2,3-Dihydro-3,3-dimethyl-1,2-benzisothiazole 1,1-dioxide chemical structure, C9H11NO2S, CAS 102362-98-1
2,3-Dihydro-3,3-dimethyl-1,2-benzisothiazole 1,1-dioxide
CAS 102362-98-1C9H11NO2S
2-Fluoro-3,3-dimethyl-2,3-dihydro-1,2-benzisothiazole 1,1-dioxide chemical structure, C9H10FNO2S, CAS 124170-23-6
2-Fluoro-3,3-dimethyl-2,3-dihydro-1,2-benzisothiazole 1,1-dioxide
CAS 124170-23-6C9H10FNO2S
(S)-3-Methyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide chemical structure, C8H9NO2S, CAS 130973-57-8
(S)-3-Methyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide
CAS 130973-57-8C8H9NO2S
3-Methyl-2,3-dihydro-1H-1lambda~6~,2-benzothiazole-1,1-dione chemical structure, C8H9NO2S, CAS 84108-98-5
3-Methyl-2,3-dihydro-1H-1lambda~6~,2-benzothiazole-1,1-dione
CAS 84108-98-5C8H9NO2S
7-Bromo-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione chemical structure, C7H6BrNO2S, CAS 300710-05-8
7-Bromo-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
CAS 300710-05-8C7H6BrNO2S
7-Bromo-2-methyl-3H-1,2-benzothiazole 1,1-dioxide chemical structure, C8H8BrNO2S, CAS 300710-08-1
7-Bromo-2-methyl-3H-1,2-benzothiazole 1,1-dioxide
CAS 300710-08-1C8H8BrNO2S
1,2-Benzisothiazole, 3-butyl-2,3-dihydro-, 1,1-dioxide chemical structure, C11H15NO2S, CAS 84108-99-6
1,2-Benzisothiazole, 3-butyl-2,3-dihydro-, 1,1-dioxide
CAS 84108-99-6C11H15NO2S
5-Fluoro-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide chemical structure, C7H6FNO2S, CAS 845644-47-5
5-Fluoro-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide
CAS 845644-47-5C7H6FNO2S
2,3-Dihydro-2-methyl-1,2-benzisothiazole-1,1-dione chemical structure, C8H9NO2S, CAS 67299-16-5
2,3-Dihydro-2-methyl-1,2-benzisothiazole-1,1-dione
CAS 67299-16-5C8H9NO2S
5-Hydroxy-3,3-dimethyl-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione chemical structure, C9H11NO3S, CAS 463341-43-7
5-Hydroxy-3,3-dimethyl-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
CAS 463341-43-7C9H11NO3S
7-Chloro-2,3-dihydrobenzo[d]isothiazole 1,1-Dioxide chemical structure, C7H6ClNO2S, CAS 92811-13-7
7-Chloro-2,3-dihydrobenzo[d]isothiazole 1,1-Dioxide
CAS 92811-13-7C7H6ClNO2S
(R)-3-Methyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide chemical structure, C8H9NO2S, CAS 130973-53-4
(R)-3-Methyl-2,3-dihydrobenzo[d]isothiazole 1,1-dioxide
CAS 130973-53-4C8H9NO2S
5-Hydroxy-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione chemical structure, C7H7NO3S, CAS 43059-32-1
5-Hydroxy-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
CAS 43059-32-1C7H7NO3S
3,3-Dimethyl-6-nitro-2,3-dihydro-benzo[d]isothiazole 1,1-dioxide chemical structure, C9H10N2O4S, CAS 140837-70-3
3,3-Dimethyl-6-nitro-2,3-dihydro-benzo[d]isothiazole 1,1-dioxide
CAS 140837-70-3C9H10N2O4S
6-Chloro-2,3-dihydrobenzo[d]isothiazole 1,1-Dioxide chemical structure, C7H6ClNO2S, CAS 950668-10-7
6-Chloro-2,3-dihydrobenzo[d]isothiazole 1,1-Dioxide
CAS 950668-10-7C7H6ClNO2S
6-Amino-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione chemical structure, C7H8N2O2S, CAS 916438-46-5
6-Amino-2,3-dihydro-1lambda6,2-benzothiazole-1,1-dione
CAS 916438-46-5C7H8N2O2S