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Murcko scaffold

1H,7H-(1,2,4)Triazolo(1,5-a)pyrimidin-7-one scaffold

227 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
227
With full pages
57
Scaffold SMILES

O=c1ccnc2nc[nH]n12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1H,7H-(1,2,4)Triazolo(1,5-a)pyrimidin-7-one page
Murcko scaffold O=c1ccnc2nc[nH]n12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 227 chemicals

(1,2,4)Triazolo(1,5-a)pyrimidin-7-ol, 5-methyl- chemical structure, C6H6N4O, CAS 2503-56-2
(1,2,4)Triazolo(1,5-a)pyrimidin-7-ol, 5-methyl-
CAS 2503-56-2C6H6N4O
GNF-Pf-1227 chemical structure, C9H10N4O3, CAS 5797-96-6
GNF-Pf-1227
CAS 5797-96-6C9H10N4O3
[1,2,4]Triazolo[1,5-a]pyrimidin-7(1H)-one, 2-(chloromethyl)-5-methyl- chemical structure, C7H7ClN4O, CAS 56433-30-8
[1,2,4]Triazolo[1,5-a]pyrimidin-7(1H)-one, 2-(chloromethyl)-5-methyl-
CAS 56433-30-8C7H7ClN4O
[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl-2-(methylthio)- chemical structure, C7H8N4OS, CAS 40775-78-8
[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 5-methyl-2-(methylthio)-
CAS 40775-78-8C7H8N4OS
7-Hydroxy-5-methyl-2-(methylthio)-1,2,4-triazolo(1,5-a)pyrimidine-6-carboxylic acid chemical structure, C8H8N4O3S, CAS 63059-40-5
7-Hydroxy-5-methyl-2-(methylthio)-1,2,4-triazolo(1,5-a)pyrimidine-6-carboxylic acid
CAS 63059-40-5C8H8N4O3S
Ethyl 7-hydroxy-5-methyl-2-(methylthio)(1,2,4)triazolo(1,5-a)pyrimidine-6-carboxylate chemical structure, C10H12N4O3S, CAS 63123-21-7
Ethyl 7-hydroxy-5-methyl-2-(methylthio)(1,2,4)triazolo(1,5-a)pyrimidine-6-carboxylate
CAS 63123-21-7C10H12N4O3S
[1,2,4]Triazolo[1,5-a]pyrimidine-2-carboxylic acid, 7-hydroxy-5-methyl-, methyl ester chemical structure, C8H8N4O3, CAS 63665-74-7
[1,2,4]Triazolo[1,5-a]pyrimidine-2-carboxylic acid, 7-hydroxy-5-methyl-, methyl ester
CAS 63665-74-7C8H8N4O3
[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl- chemical structure, C6H5BrN4O, CAS 32449-41-5
[1,2,4]Triazolo[1,5-a]pyrimidin-7-ol, 6-bromo-5-methyl-
CAS 32449-41-5C6H5BrN4O
(1,2,4)Triazolo(1,5-a)pyrimidine-2-carboxylic acid, 7-hydroxy-5-methyl- chemical structure, C7H6N4O3, CAS 40775-86-8
(1,2,4)Triazolo(1,5-a)pyrimidine-2-carboxylic acid, 7-hydroxy-5-methyl-
CAS 40775-86-8C7H6N4O3
Ethyl 7-hydroxy[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C8H8N4O3, CAS 89977-78-6
Ethyl 7-hydroxy[1,2,4]triazolo[1,5-a]pyrimidine-6-carboxylate
CAS 89977-78-6C8H8N4O3
2-Amino-5-methyl-3H,7H-(1,2,4)triazolo(1,5-a)pyrimidin-7-one chemical structure, C6H7N5O, CAS 72436-99-8
2-Amino-5-methyl-3H,7H-(1,2,4)triazolo(1,5-a)pyrimidin-7-one
CAS 72436-99-8C6H7N5O
5-Methyl-2-(trifluoromethyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one chemical structure, C7H5F3N4O, CAS 198953-53-6
5-Methyl-2-(trifluoromethyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
CAS 198953-53-6C7H5F3N4O
[1,2,4]Triazolo[1,5-a]pyrimidin-7(1H)-one, 5-methyl-6-nitro- chemical structure, C6H5N5O3, CAS 103778-83-2
[1,2,4]Triazolo[1,5-a]pyrimidin-7(1H)-one, 5-methyl-6-nitro-
CAS 103778-83-2C6H5N5O3
1H,7H-(1,2,4)Triazolo(1,5-a)pyrimidin-7-one chemical structure, C5H4N4O, CAS 31592-08-2
1H,7H-(1,2,4)Triazolo(1,5-a)pyrimidin-7-one
CAS 31592-08-2C5H4N4O
2-Amino-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one chemical structure, C8H11N5O, CAS 299923-10-7
2-Amino-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(3H)-one
CAS 299923-10-7C8H11N5O
2-Amino-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol chemical structure, C6H4F3N5O, CAS 326906-13-2
2-Amino-5-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol
CAS 326906-13-2C6H4F3N5O
5-Methyl-6-(3-methylbutyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C11H16N4O, CAS 726200-95-9
5-Methyl-6-(3-methylbutyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 726200-95-9C11H16N4O
Methyl 2-(7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)acetate chemical structure, C9H10N4O3, CAS 477871-90-2
Methyl 2-(7-hydroxy-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-6-yl)acetate
CAS 477871-90-2C9H10N4O3
Methyl (2-methyl-7-oxo-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)acetate chemical structure, C9H10N4O3, CAS 728883-76-9
Methyl (2-methyl-7-oxo-4,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-5-yl)acetate
CAS 728883-76-9C9H10N4O3
2-Methyl-5-propyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one chemical structure, C9H12N4O, CAS 774560-69-9
2-Methyl-5-propyl-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one
CAS 774560-69-9C9H12N4O
5-Propyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol chemical structure, C8H10N4O, CAS 40775-87-9
5-Propyl(1,2,4)triazolo(1,5-a)pyrimidin-7-ol
CAS 40775-87-9C8H10N4O
5-(Methoxymethyl)-2-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C8H10N4O2, CAS 774560-70-2
5-(Methoxymethyl)-2-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 774560-70-2C8H10N4O2
5-(Methoxymethyl)-2-(methylthio)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C8H10N4O2S, CAS 774561-81-8
5-(Methoxymethyl)-2-(methylthio)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 774561-81-8C8H10N4O2S
2-Amino-5-tert-butyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one chemical structure, C9H13N5O, CAS 385377-55-9
2-Amino-5-tert-butyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
CAS 385377-55-9C9H13N5O