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Murcko scaffold

Ring system with 3 rings and 17 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
14
With full pages
4
Scaffold SMILES

c1ccc(Nc2ncnc3cnccc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Nc2ncnc3cnccc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Pd 158780 chemical structure, C14H12BrN5, CAS 171179-06-9
Pd 158780
CAS 171179-06-9C14H12BrN5
N-(3-Bromophenyl)pyrido[3,4-d]pyrimidin-4-amine chemical structure, C13H9BrN4, CAS 171179-02-5
N-(3-Bromophenyl)pyrido[3,4-d]pyrimidin-4-amine
CAS 171179-02-5C13H9BrN4
4-N-(3-Bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine chemical structure, C13H10BrN5, CAS 175357-96-7
4-N-(3-Bromophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine
CAS 175357-96-7C13H10BrN5
N-(3-Bromophenyl)-6-chloropyrido[3,4-d]pyrimidin-4-amine chemical structure, C13H8BrClN4, CAS 171179-04-7
N-(3-Bromophenyl)-6-chloropyrido[3,4-d]pyrimidin-4-amine
CAS 171179-04-7C13H8BrClN4
N-(3-Bromophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine chemical structure, C13H8BrFN4, CAS 171179-03-6
N-(3-Bromophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine
CAS 171179-03-6C13H8BrFN4
4-N-(3-Bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine chemical structure, C15H14BrN5, CAS 171178-54-4
4-N-(3-Bromophenyl)-6-N,6-N-dimethylpyrido[3,4-d]pyrimidine-4,6-diamine
CAS 171178-54-4C15H14BrN5
N-(3-Bromophenyl)-6-methoxypyrido[3,4-d]pyrimidin-4-amine chemical structure, C14H11BrN4O, CAS 171179-05-8
N-(3-Bromophenyl)-6-methoxypyrido[3,4-d]pyrimidin-4-amine
CAS 171179-05-8C14H11BrN4O
N4-(3-bromo-4-fluorophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine chemical structure, C13H9BrFN5, CAS 227311-92-4
N4-(3-bromo-4-fluorophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine
CAS 227311-92-4C13H9BrFN5
N4-(3-chloro-4-fluorophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine chemical structure, C13H9ClFN5, CAS 227311-93-5
N4-(3-chloro-4-fluorophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine
CAS 227311-93-5C13H9ClFN5
EGFR/ErbB-2/ErbB-4 inhibitor chemical structure, C17H11ClFN5O, CAS 881001-19-0
EGFR/ErbB-2/ErbB-4 inhibitor
CAS 881001-19-0C17H11ClFN5O
Tarlox-TKI chemical structure, C19H18BrClN6O, CAS 2135696-72-7
Tarlox-TKI
CAS 2135696-72-7C19H18BrClN6O
N-(3-Bromo-4-chlorophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine chemical structure, C13H7BrClFN4, CAS 2135696-73-8
N-(3-Bromo-4-chlorophenyl)-6-fluoropyrido[3,4-d]pyrimidin-4-amine
CAS 2135696-73-8C13H7BrClFN4
N4-(3-bromo-4-chlorophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine chemical structure, C13H9BrClN5, CAS 2135696-75-0
N4-(3-bromo-4-chlorophenyl)pyrido[3,4-d]pyrimidine-4,6-diamine
CAS 2135696-75-0C13H9BrClN5
Diethyl (2-((4-((3-bromo-4-chlorophenyl)amino)pyrido[3,4-d]pyrimidin-6-yl)amino)-2-oxoethyl)phosphonate chemical structure, C19H20BrClN5O4P, CAS 2135696-76-1
Diethyl (2-((4-((3-bromo-4-chlorophenyl)amino)pyrido[3,4-d]pyrimidin-6-yl)amino)-2-oxoethyl)phosphonate
CAS 2135696-76-1C19H20BrClN5O4P