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Murcko scaffold

N1-phenyl-N2-(pyridin-2-ylmethyl)oxalamide scaffold

35 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
35
With full pages
15
Scaffold SMILES

O=C(NCc1ccccn1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N1-phenyl-N2-(pyridin-2-ylmethyl)oxalamide page
Murcko scaffold O=C(NCc1ccccn1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 35 of 35 chemicals

N'-(2,4-Dimethoxyphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C16H17N3O4, CAS 351890-94-3
N'-(2,4-Dimethoxyphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 351890-94-3C16H17N3O4
N'-(4-Chlorophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H12ClN3O2, CAS 352013-11-7
N'-(4-Chlorophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 352013-11-7C14H12ClN3O2
N-(4-Bromophenyl)-N'-(pyridin-2-ylmethyl)ethanediamide chemical structure, C14H12BrN3O2, CAS 352013-12-8
N-(4-Bromophenyl)-N'-(pyridin-2-ylmethyl)ethanediamide
CAS 352013-12-8C14H12BrN3O2
N'-(5-Chloro-2-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C15H14ClN3O2, CAS 371929-01-0
N'-(5-Chloro-2-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 371929-01-0C15H14ClN3O2
N'-(2-Methoxy-5-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C16H17N3O3, CAS 332147-36-1
N'-(2-Methoxy-5-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 332147-36-1C16H17N3O3
N'-(4-Fluorophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H12FN3O2, CAS 331863-42-4
N'-(4-Fluorophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 331863-42-4C14H12FN3O2
N'-(2,3-Dichlorophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H11Cl2N3O2, CAS 496940-74-0
N'-(2,3-Dichlorophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 496940-74-0C14H11Cl2N3O2
N1-(2,6-dimethylphenyl)-N2-(pyridin-2-ylmethyl)oxalamide chemical structure, C16H17N3O2, CAS 690683-31-9
N1-(2,6-dimethylphenyl)-N2-(pyridin-2-ylmethyl)oxalamide
CAS 690683-31-9C16H17N3O2
N'-(2-Fluorophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H12FN3O2, CAS 351897-95-5
N'-(2-Fluorophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 351897-95-5C14H12FN3O2
N'-(2-Chlorophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H12ClN3O2, CAS 403813-84-3
N'-(2-Chlorophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 403813-84-3C14H12ClN3O2
N-(2-Methoxyphenyl)-N'-(pyridin-2-ylmethyl)ethanediamide chemical structure, C15H15N3O3, CAS 352013-18-4
N-(2-Methoxyphenyl)-N'-(pyridin-2-ylmethyl)ethanediamide
CAS 352013-18-4C15H15N3O3
N-(3-Methoxyphenyl)-N'-(pyridin-2-ylmethyl)ethanediamide chemical structure, C15H15N3O3, CAS 329715-65-3
N-(3-Methoxyphenyl)-N'-(pyridin-2-ylmethyl)ethanediamide
CAS 329715-65-3C15H15N3O3
N'-(4-Methoxyphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C15H15N3O3, CAS 331426-60-9
N'-(4-Methoxyphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 331426-60-9C15H15N3O3
N-Pyridin-2-ylmethyl-N'-o-tolyl-oxalamide chemical structure, C15H15N3O2, CAS 6198-87-4
N-Pyridin-2-ylmethyl-N'-o-tolyl-oxalamide
CAS 6198-87-4C15H15N3O2
N'-(3,5-Dimethylphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C16H17N3O2, CAS 6221-09-6
N'-(3,5-Dimethylphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 6221-09-6C16H17N3O2
N'-(5-Chloro-2-methoxyphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C15H14ClN3O3, CAS 330460-12-3
N'-(5-Chloro-2-methoxyphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 330460-12-3C15H14ClN3O3
N'-(4-Nitrophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H12N4O4, CAS 6198-88-5
N'-(4-Nitrophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 6198-88-5C14H12N4O4
N'-(2,4-Difluorophenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C14H11F2N3O2, CAS 838899-15-3
N'-(2,4-Difluorophenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 838899-15-3C14H11F2N3O2
N1-(3-fluorophenyl)-N2-(pyridin-2-ylmethyl)oxalamide chemical structure, C14H12FN3O2, CAS 839685-84-6
N1-(3-fluorophenyl)-N2-(pyridin-2-ylmethyl)oxalamide
CAS 839685-84-6C14H12FN3O2
N1-phenyl-N2-(pyridin-2-ylmethyl)oxalamide chemical structure, C14H13N3O2, CAS 352013-06-0
N1-phenyl-N2-(pyridin-2-ylmethyl)oxalamide
CAS 352013-06-0C14H13N3O2
N'-(4-Methylphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C15H15N3O2, CAS 352013-07-1
N'-(4-Methylphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 352013-07-1C15H15N3O2
N'-(3-Chloro-4-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C15H14ClN3O2, CAS 810694-90-7
N'-(3-Chloro-4-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 810694-90-7C15H14ClN3O2
N'-(3-Chloro-2-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide chemical structure, C15H14ClN3O2, CAS 797813-85-5
N'-(3-Chloro-2-methylphenyl)-N-(pyridin-2-ylmethyl)oxamide
CAS 797813-85-5C15H14ClN3O2
N-Pyridin-2-ylmethyl-N'-m-tolyl-oxalamide chemical structure, C15H15N3O2, CAS 499111-37-4
N-Pyridin-2-ylmethyl-N'-m-tolyl-oxalamide
CAS 499111-37-4C15H15N3O2