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Murcko scaffold

Ring system with 4 rings and 19 atoms

25 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
25
With full pages
4
Scaffold SMILES

O=C1CCC2C(CCC3C4CCCC4CC(=O)C23)C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCC2C(CCC3C4CCCC4CC(=O)C23)C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

4,5beta-Dihydrocortisone chemical structure, C21H30O5, CAS 68-54-2
4,5beta-Dihydrocortisone
CAS 68-54-2C21H30O5
(5Beta)pregnane-3,11,20-trione chemical structure, C21H30O3, CAS 1474-68-6
(5Beta)pregnane-3,11,20-trione
CAS 1474-68-6C21H30O3
17,21-Dihydroxy-5alpha-pregnane-3,11,20-trione 21-acetate chemical structure, C23H32O6
17,21-Dihydroxy-5alpha-pregnane-3,11,20-trione 21-acetate
C23H32O6
17-Hydroxy-3,11,20-trioxopregnan-21-yl acetate chemical structure, C23H32O6, CAS 3751-02-8
17-Hydroxy-3,11,20-trioxopregnan-21-yl acetate
CAS 3751-02-8C23H32O6
(5R,8S,9S,10S,13S,14S,17S)-17-Hydroxy-10,13,17-trimethyl-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,11-dione chemical structure, C20H30O3, CAS 59962-27-5
(5R,8S,9S,10S,13S,14S,17S)-17-Hydroxy-10,13,17-trimethyl-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,11-dione
CAS 59962-27-5C20H30O3
4-Chloro-17-hydroxy-3,11,20-trioxopregnan-21-yl acetate chemical structure, C23H31ClO6, CAS 5422-85-5
4-Chloro-17-hydroxy-3,11,20-trioxopregnan-21-yl acetate
CAS 5422-85-5C23H31ClO6
17-Hydroxy-5beta-pregnane-3,11,20-trione chemical structure, C21H30O4, CAS 10455-93-3
17-Hydroxy-5beta-pregnane-3,11,20-trione
CAS 10455-93-3C21H30O4
Dihydrocortisone acetate chemical structure, C23H32O6, CAS 1499-59-8
Dihydrocortisone acetate
CAS 1499-59-8C23H32O6
Androstane-3,11-dione, 9-fluoro-17-hydroxy-17-methyl-, (5beta,17beta)- chemical structure, C20H29FO3, CAS 1584-44-7
Androstane-3,11-dione, 9-fluoro-17-hydroxy-17-methyl-, (5beta,17beta)-
CAS 1584-44-7C20H29FO3
(5S,8S,9R,10S,13S,14S,17S)-9-Fluoro-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione chemical structure, C20H29FO3, CAS 59981-94-1
(5S,8S,9R,10S,13S,14S,17S)-9-Fluoro-17-hydroxy-10,13,17-trimethyl-2,4,5,6,7,8,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione
CAS 59981-94-1C20H29FO3
[2-[(4S,5R,8S,9S,10R,13S,14S,17R)-4-Bromo-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate chemical structure, C23H31BrO6, CAS 50304-19-3
[2-[(4S,5R,8S,9S,10R,13S,14S,17R)-4-Bromo-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
CAS 50304-19-3C23H31BrO6
21-Hydroxy-5beta-pregnane-3,11,20-trione chemical structure, C21H30O4, CAS 10417-86-4
21-Hydroxy-5beta-pregnane-3,11,20-trione
CAS 10417-86-4C21H30O4
[2-[(4R,5S,8S,9S,10R,13S,14S,17R)-4-Bromo-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate chemical structure, C23H31BrO6, CAS 74243-24-6
[2-[(4R,5S,8S,9S,10R,13S,14S,17R)-4-Bromo-17-hydroxy-10,13-dimethyl-3,11-dioxo-1,2,4,5,6,7,8,9,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
CAS 74243-24-6C23H31BrO6
17-Hydroxypregnane-3,11,20-trione chemical structure, C21H30O4, CAS 1923-68-8
17-Hydroxypregnane-3,11,20-trione
CAS 1923-68-8C21H30O4
4,5alpha-Dihydrocortisone chemical structure, C21H30O5, CAS 1482-51-5
4,5alpha-Dihydrocortisone
CAS 1482-51-5C21H30O5
5alpha-Pregnane-3,11,20-trione chemical structure, C21H30O3, CAS 2089-06-7
5alpha-Pregnane-3,11,20-trione
CAS 2089-06-7C21H30O3
11-Ketodihydrotestosterone chemical structure, C19H28O3, CAS 32694-37-4
11-Ketodihydrotestosterone
CAS 32694-37-4C19H28O3
5alpha-Dihydrocortisone 21-Acetate chemical structure, C23H32O6
5alpha-Dihydrocortisone 21-Acetate
C23H32O6
21-Chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)pregnane-3,11,20-trione, (5beta,16beta)- chemical structure, C25H34ClFO5, CAS 80163-80-0
21-Chloro-9-fluoro-16-methyl-17-(1-oxopropoxy)pregnane-3,11,20-trione, (5beta,16beta)-
CAS 80163-80-0C25H34ClFO5
5-Dihydrocortisone chemical structure, C21H30O5, CAS 28423-48-5
5-Dihydrocortisone
CAS 28423-48-5C21H30O5
Lanostane-3,11-dione chemical structure, C30H50O2, CAS 50764-37-9
Lanostane-3,11-dione
CAS 50764-37-9C30H50O2
21-Hydroxy-5alpha-pregnane-3,11,20-trione chemical structure, C21H30O4, CAS 51297-06-4
21-Hydroxy-5alpha-pregnane-3,11,20-trione
CAS 51297-06-4C21H30O4
Pregnane-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, (5beta)- chemical structure, C23H32O6
Pregnane-3,11,20-trione, 21-(acetyloxy)-17-hydroxy-, (5beta)-
C23H32O6
11-Ketodihydrotestosterone-d3 chemical structure, C19H28O3, CAS 2479914-02-6
11-Ketodihydrotestosterone-d3
CAS 2479914-02-6C19H28O3