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Murcko scaffold

2-Oxo-N-phenyl-2,3-dihydro-1H-benzimidazole-5-sulfonamide scaffold

24 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
24
With full pages
15
Scaffold SMILES

O=c1[nH]c2ccc(S(=O)(=O)Nc3ccccc3)cc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Oxo-N-phenyl-2,3-dihydro-1H-benzimidazole-5-sulfonamide page
Murcko scaffold O=c1[nH]c2ccc(S(=O)(=O)Nc3ccccc3)cc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-Oxo-N-(m-tolyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide chemical structure, C14H13N3O3S, CAS 591213-63-7
2-Oxo-N-(m-tolyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide
CAS 591213-63-7C14H13N3O3S
N-(2-Methoxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C14H13N3O4S, CAS 701950-51-8
N-(2-Methoxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 701950-51-8C14H13N3O4S
2-(2-Oxo-2,3-dihydro-1H-1,3-benzodiazole-5-sulfonamido)benzoic acid chemical structure, C14H11N3O5S, CAS 701275-61-8
2-(2-Oxo-2,3-dihydro-1H-1,3-benzodiazole-5-sulfonamido)benzoic acid
CAS 701275-61-8C14H11N3O5S
N-(2,5-Dimethoxyphenyl)-1,3-dimethyl-2-oxobenzimidazole-5-sulfonamide chemical structure, C17H19N3O5S, CAS 701224-53-5
N-(2,5-Dimethoxyphenyl)-1,3-dimethyl-2-oxobenzimidazole-5-sulfonamide
CAS 701224-53-5C17H19N3O5S
N-[2-Ethoxy-5-(trifluoromethyl)phenyl]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide chemical structure, C18H18F3N3O4S, CAS 543694-29-7
N-[2-Ethoxy-5-(trifluoromethyl)phenyl]-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide
CAS 543694-29-7C18H18F3N3O4S
2-Oxo-N-[3-(trifluoromethyl)phenyl]-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C14H10F3N3O3S, CAS 708243-72-5
2-Oxo-N-[3-(trifluoromethyl)phenyl]-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 708243-72-5C14H10F3N3O3S
4-(2-Oxo-2,3-dihydro-1H-1,3-benzodiazole-5-sulfonamido)benzoic acid chemical structure, C14H11N3O5S, CAS 726155-15-3
4-(2-Oxo-2,3-dihydro-1H-1,3-benzodiazole-5-sulfonamido)benzoic acid
CAS 726155-15-3C14H11N3O5S
N-(3,5-Dimethylphenyl)-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide chemical structure, C15H15N3O3S, CAS 701923-47-9
N-(3,5-Dimethylphenyl)-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide
CAS 701923-47-9C15H15N3O3S
N-Ethyl-2-oxo-N-phenyl-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C15H15N3O3S, CAS 692761-85-6
N-Ethyl-2-oxo-N-phenyl-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 692761-85-6C15H15N3O3S
N-(3,4-Dimethylphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C15H15N3O3S, CAS 701969-93-9
N-(3,4-Dimethylphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 701969-93-9C15H15N3O3S
N-(2-Hydroxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C13H11N3O4S, CAS 706775-15-7
N-(2-Hydroxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 706775-15-7C13H11N3O4S
N-(2-Methoxy-5-methylphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C15H15N3O4S, CAS 708214-79-3
N-(2-Methoxy-5-methylphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 708214-79-3C15H15N3O4S
2-Oxo-N-phenyl-2,3-dihydro-1H-benzimidazole-5-sulfonamide chemical structure, C13H11N3O3S, CAS 708239-87-6
2-Oxo-N-phenyl-2,3-dihydro-1H-benzimidazole-5-sulfonamide
CAS 708239-87-6C13H11N3O3S
N-(4-Ethoxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C15H15N3O4S, CAS 708241-82-1
N-(4-Ethoxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 708241-82-1C15H15N3O4S
N-(2,4-Dimethylphenyl)-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide chemical structure, C15H15N3O3S, CAS 692279-32-6
N-(2,4-Dimethylphenyl)-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide
CAS 692279-32-6C15H15N3O3S
2-Oxo-N-(o-tolyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide chemical structure, C14H13N3O3S, CAS 778622-81-4
2-Oxo-N-(o-tolyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide
CAS 778622-81-4C14H13N3O3S
N,1,3,6-tetramethyl-2-oxo-N-phenyl-2,3-dihydro-1H-benzimidazole-5-sulfonamide chemical structure, C17H19N3O3S, CAS 878427-95-3
N,1,3,6-tetramethyl-2-oxo-N-phenyl-2,3-dihydro-1H-benzimidazole-5-sulfonamide
CAS 878427-95-3C17H19N3O3S
Ethyl N-[2-methoxy-4-[(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)sulfonylamino]phenyl]carbamate chemical structure, C20H24N4O6S, CAS 881594-02-1
Ethyl N-[2-methoxy-4-[(1,3,6-trimethyl-2-oxobenzimidazol-5-yl)sulfonylamino]phenyl]carbamate
CAS 881594-02-1C20H24N4O6S
N-(3-Chlorophenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C13H10ClN3O3S, CAS 881046-15-7
N-(3-Chlorophenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 881046-15-7C13H10ClN3O3S
2-Oxo-N-(2,4,6-trimethylphenyl)-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C16H17N3O3S, CAS 865613-78-1
2-Oxo-N-(2,4,6-trimethylphenyl)-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 865613-78-1C16H17N3O3S
2-Oxo-N-(p-tolyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide chemical structure, C14H13N3O3S, CAS 865613-84-9
2-Oxo-N-(p-tolyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide
CAS 865613-84-9C14H13N3O3S
N-(4-Chlorophenyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide chemical structure, C15H14ClN3O3S, CAS 879646-19-2
N-(4-Chlorophenyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide
CAS 879646-19-2C15H14ClN3O3S
N-(3-Methoxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide chemical structure, C14H13N3O4S, CAS 1189900-14-8
N-(3-Methoxyphenyl)-2-oxo-1,3-dihydrobenzimidazole-5-sulfonamide
CAS 1189900-14-8C14H13N3O4S
Sulfonamido)benzamide chemical structure, C19H21N5O5S, CAS 2035085-19-7
Sulfonamido)benzamide
CAS 2035085-19-7C19H21N5O5S