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Murcko scaffold

Ring system with 3 rings and 18 atoms

81 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
81
With full pages
15
Scaffold SMILES

O=C(Nc1ccc2[nH]cnc2c1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc2[nH]cnc2c1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 81 chemicals

N-(1-Methyl-1H-benzimidazol-5-yl)benzamide chemical structure, C15H13N3O, CAS 309724-61-6
N-(1-Methyl-1H-benzimidazol-5-yl)benzamide
CAS 309724-61-6C15H13N3O
N-(1-tert-Butylbenzimidazol-5-yl)benzamide chemical structure, C18H19N3O, CAS 335397-23-4
N-(1-tert-Butylbenzimidazol-5-yl)benzamide
CAS 335397-23-4C18H19N3O
N-(1,2-Dimethylbenzimidazol-5-yl)-4-methylbenzamide chemical structure, C17H17N3O, CAS 335397-24-5
N-(1,2-Dimethylbenzimidazol-5-yl)-4-methylbenzamide
CAS 335397-24-5C17H17N3O
4-Methyl-N-(1-methylbenzimidazol-5-yl)benzamide chemical structure, C16H15N3O, CAS 381696-06-6
4-Methyl-N-(1-methylbenzimidazol-5-yl)benzamide
CAS 381696-06-6C16H15N3O
4-Chloro-N-(1-methylbenzimidazol-5-yl)benzamide chemical structure, C15H12ClN3O, CAS 489464-52-0
4-Chloro-N-(1-methylbenzimidazol-5-yl)benzamide
CAS 489464-52-0C15H12ClN3O
N-(1-tert-Butylbenzimidazol-5-yl)-4-chlorobenzamide chemical structure, C18H18ClN3O, CAS 497247-81-1
N-(1-tert-Butylbenzimidazol-5-yl)-4-chlorobenzamide
CAS 497247-81-1C18H18ClN3O
4-Chloro-N-(1,2-dimethyl-5-benzimidazolyl)benzamide chemical structure, C16H14ClN3O, CAS 497242-15-6
4-Chloro-N-(1,2-dimethyl-5-benzimidazolyl)benzamide
CAS 497242-15-6C16H14ClN3O
N-(1,2-Dimethylbenzimidazol-5-yl)-3,4,5-trimethoxybenzamide chemical structure, C19H21N3O4, CAS 498535-73-2
N-(1,2-Dimethylbenzimidazol-5-yl)-3,4,5-trimethoxybenzamide
CAS 498535-73-2C19H21N3O4
N-(1-tert-Butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide chemical structure, C21H25N3O4, CAS 497240-67-2
N-(1-tert-Butyl-5-benzimidazolyl)-3,4,5-trimethoxybenzamide
CAS 497240-67-2C21H25N3O4
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]benzamide chemical structure, C19H20N4O2, CAS 831234-23-2
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]benzamide
CAS 831234-23-2C19H20N4O2
3,4,5-Trimethoxy-N-(1-propan-2-ylbenzimidazol-5-yl)benzamide chemical structure, C20H23N3O4, CAS 831206-91-8
3,4,5-Trimethoxy-N-(1-propan-2-ylbenzimidazol-5-yl)benzamide
CAS 831206-91-8C20H23N3O4
N-{2-[2-(Acetylamino)ethyl]-1-methyl-1H-benzimidazol-5-yl}-2-methoxybenzamide chemical structure, C20H22N4O3, CAS 830353-06-5
N-{2-[2-(Acetylamino)ethyl]-1-methyl-1H-benzimidazol-5-yl}-2-methoxybenzamide
CAS 830353-06-5C20H22N4O3
3-Bromo-N-[1-methyl-2-[2-(propanoylamino)ethyl]benzimidazol-5-yl]benzamide chemical structure, C20H21BrN4O2, CAS 904007-74-5
3-Bromo-N-[1-methyl-2-[2-(propanoylamino)ethyl]benzimidazol-5-yl]benzamide
CAS 904007-74-5C20H21BrN4O2
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]-4-chlorobenzamide chemical structure, C19H19ClN4O2, CAS 876710-51-9
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]-4-chlorobenzamide
CAS 876710-51-9C19H19ClN4O2
N-(2-Methyl-1H-benzimidazol-5-yl)-4-nitrobenzamide chemical structure, C15H12N4O3, CAS 690692-64-9
N-(2-Methyl-1H-benzimidazol-5-yl)-4-nitrobenzamide
CAS 690692-64-9C15H12N4O3
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]-4-nitrobenzamide chemical structure, C19H19N5O4, CAS 895831-84-2
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]-4-nitrobenzamide
CAS 895831-84-2C19H19N5O4
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]-3-nitrobenzamide chemical structure, C19H19N5O4, CAS 879757-74-1
N-[2-(2-Acetamidoethyl)-1-methylbenzimidazol-5-yl]-3-nitrobenzamide
CAS 879757-74-1C19H19N5O4
N-(3H-Benzimidazol-5-yl)-3,4-dimethoxybenzamide chemical structure, C16H15N3O3, CAS 853903-18-1
N-(3H-Benzimidazol-5-yl)-3,4-dimethoxybenzamide
CAS 853903-18-1C16H15N3O3
N-(1-Ethylbenzimidazol-5-yl)-2-fluorobenzamide chemical structure, C16H14FN3O, CAS 879586-60-4
N-(1-Ethylbenzimidazol-5-yl)-2-fluorobenzamide
CAS 879586-60-4C16H14FN3O
2-Bromo-N-(2-methyl-1H-benzimidazol-5-yl)benzamide chemical structure, C15H12BrN3O, CAS 930476-76-9
2-Bromo-N-(2-methyl-1H-benzimidazol-5-yl)benzamide
CAS 930476-76-9C15H12BrN3O
N-(2-Methyl-1H-1,3-benzodiazol-5-yl)benzamide chemical structure, C15H13N3O, CAS 82326-54-3
N-(2-Methyl-1H-1,3-benzodiazol-5-yl)benzamide
CAS 82326-54-3C15H13N3O
2-Methoxy-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C16H12F3N3O2, CAS 1190275-57-0
2-Methoxy-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1190275-57-0C16H12F3N3O2
3,4,5-Trimethoxy-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C18H16F3N3O4, CAS 1190267-43-6
3,4,5-Trimethoxy-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1190267-43-6C18H16F3N3O4
2-Fluoro-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide chemical structure, C15H9F4N3O, CAS 1190257-79-4
2-Fluoro-N-[2-(trifluoromethyl)-1H-benzimidazol-5-yl]benzamide
CAS 1190257-79-4C15H9F4N3O