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Murcko scaffold

N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide scaffold

94 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
94
With full pages
27
Scaffold SMILES

O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide page
Murcko scaffold O=C(Nc1ccc2c(c1)C(=O)NC2=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 94 chemicals

4-Ethoxy-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide chemical structure, C18H16N2O4, CAS 315240-71-2
4-Ethoxy-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide
CAS 315240-71-2C18H16N2O4
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide chemical structure, C15H10N2O3, CAS 49545-91-7
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide
CAS 49545-91-7C15H10N2O3
Benzamide, 2,4-dichloro-N-(2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl)- chemical structure, C15H8Cl2N2O3, CAS 312928-65-7
Benzamide, 2,4-dichloro-N-(2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl)-
CAS 312928-65-7C15H8Cl2N2O3
3-Chloro-4-methyl-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide chemical structure, C17H13ClN2O3, CAS 433319-55-2
3-Chloro-4-methyl-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide
CAS 433319-55-2C17H13ClN2O3
2,4-Dimethoxy-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide chemical structure, C18H16N2O5, CAS 318513-51-8
2,4-Dimethoxy-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide
CAS 318513-51-8C18H16N2O5
N-(1,3-Dioxoisoindolin-5-yl)-4-nitrobenzamide chemical structure, C15H9N3O5, CAS 312759-14-1
N-(1,3-Dioxoisoindolin-5-yl)-4-nitrobenzamide
CAS 312759-14-1C15H9N3O5
2,4-Dimethyl-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide chemical structure, C18H16N2O3, CAS 674306-86-6
2,4-Dimethyl-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide
CAS 674306-86-6C18H16N2O3
N-(2-Methyl-1,3-dioxoisoindolin-5-yl)-3-(trifluoromethyl)benzamide chemical structure, C17H11F3N2O3, CAS 330190-02-8
N-(2-Methyl-1,3-dioxoisoindolin-5-yl)-3-(trifluoromethyl)benzamide
CAS 330190-02-8C17H11F3N2O3
2,6-Difluoro-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide chemical structure, C16H10F2N2O3, CAS 325977-16-0
2,6-Difluoro-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide
CAS 325977-16-0C16H10F2N2O3
2,6-Dimethoxy-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide chemical structure, C18H16N2O5, CAS 476326-06-4
2,6-Dimethoxy-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide
CAS 476326-06-4C18H16N2O5
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-3,4-dimethylbenzamide chemical structure, C17H14N2O3, CAS 683235-50-9
N-(1,3-Dioxo-2,3-dihydro-1H-isoindol-5-yl)-3,4-dimethylbenzamide
CAS 683235-50-9C17H14N2O3
N-(1,3-Dioxoisoindol-5-yl)-2-ethoxybenzamide chemical structure, C17H14N2O4, CAS 518021-54-0
N-(1,3-Dioxoisoindol-5-yl)-2-ethoxybenzamide
CAS 518021-54-0C17H14N2O4
2-Chloro-5-iodo-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide chemical structure, C16H10ClIN2O3, CAS 433240-79-0
2-Chloro-5-iodo-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide
CAS 433240-79-0C16H10ClIN2O3
2-Bromo-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide chemical structure, C16H11BrN2O3, CAS 433317-39-6
2-Bromo-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide
CAS 433317-39-6C16H11BrN2O3
3-Iodo-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide chemical structure, C16H11IN2O3, CAS 445415-53-2
3-Iodo-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide
CAS 445415-53-2C16H11IN2O3
3,4,5-Triethoxy-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide chemical structure, C22H24N2O6, CAS 433253-24-8
3,4,5-Triethoxy-N-(2-methyl-1,3-dioxoisoindol-5-yl)benzamide
CAS 433253-24-8C22H24N2O6
4-Methoxy-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-nitrobenzamide chemical structure, C17H13N3O6, CAS 433246-76-5
4-Methoxy-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-nitrobenzamide
CAS 433246-76-5C17H13N3O6
5-Bromo-2-methoxy-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide chemical structure, C17H13BrN2O4, CAS 433243-58-4
5-Bromo-2-methoxy-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide
CAS 433243-58-4C17H13BrN2O4
2-Methoxy-N-[2-(2-methylpropyl)-1,3-dioxoisoindol-5-yl]benzamide chemical structure, C20H20N2O4, CAS 669704-16-9
2-Methoxy-N-[2-(2-methylpropyl)-1,3-dioxoisoindol-5-yl]benzamide
CAS 669704-16-9C20H20N2O4
3-Bromo-N-(1,3-dioxoisoindol-5-yl)benzamide chemical structure, C15H9BrN2O3, CAS 667403-82-9
3-Bromo-N-(1,3-dioxoisoindol-5-yl)benzamide
CAS 667403-82-9C15H9BrN2O3
2-Iodo-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide chemical structure, C16H11IN2O3, CAS 303796-88-5
2-Iodo-N-(2-methyl-1,3-dioxoisoindolin-5-yl)benzamide
CAS 303796-88-5C16H11IN2O3
4-Chloro-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-nitrobenzamide chemical structure, C16H10ClN3O5, CAS 433310-44-2
4-Chloro-N-(2-methyl-1,3-dioxoisoindol-5-yl)-3-nitrobenzamide
CAS 433310-44-2C16H10ClN3O5
3-Bromo-4-ethoxy-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide chemical structure, C18H15BrN2O4, CAS 433254-26-3
3-Bromo-4-ethoxy-N-(2-methyl-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl)benzamide
CAS 433254-26-3C18H15BrN2O4
3,4-Dichloro-N-(1,3-dioxoisoindol-5-yl)benzamide chemical structure, C15H8Cl2N2O3, CAS 831186-05-1
3,4-Dichloro-N-(1,3-dioxoisoindol-5-yl)benzamide
CAS 831186-05-1C15H8Cl2N2O3