Murcko scaffold
Dihydrobenzofuran scaffold
4,355 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 4,355
- With full pages
- 349
Scaffold SMILES
c1ccc2c(c1)CCO2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 4,355 chemicals
Carbofuran
CAS 1563-66-2C12H15NO3
Dihydrobenzofuran
CAS 496-16-2C8H8O
2,3-Dihydro-2,2-dimethyl-7-benzofuranol
CAS 1563-38-8C10H12O2
Decarbofuran
CAS 1563-67-3C11H13NO3
7-Benzofuranol, 2,3-dihydro-2,2,4-trimethyl-, 7-(N-methylcarbamate)
CAS 4785-72-2C13H17NO3
Carbamic acid, methyl-, 2,3-dihydro-7-benzofuranyl ester
CAS 4790-83-4C10H11NO3
2,3-Dihydro-2,2-dimethyl-7-benzofuranyl carbamate
CAS 4790-87-8C11H13NO3
7-Benzofuranol, 2,3-dihydro-2,2-dimethyl-, dimethylcarbamate
CAS 4790-88-9C13H17NO3
7-Benzofuranol, 4-chloro-2,3-dihydro-2,2-dimethyl-, methylcarbamate
CAS 4790-92-5C12H14ClNO3
3-Hydroxycarbofuran
CAS 16655-82-6C12H15NO4
Carbamic acid, (hydroxymethyl)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
CAS 18999-70-7C12H15NO4
(2,3-Dihydrobenzofuran-2-yl)methanamine
CAS 21214-11-9C9H11NO
2-Methylaminomethyl-2,3-dihydrobenzofuran
CAS 21130-01-8C10H13NO
N-Ethyl-2,3-dihydro-2-benzofuranmethanamine
CAS 21130-02-9C11H15NO
2,3-Dihydro-N-(1-methylethyl)-2-benzofuranmethanamine
CAS 21130-03-0C12H17NO
Ethofumesate
CAS 26225-79-6C13H18O5S
2,2-Dimethyl-2,3-dihydrobenzofuranyl-7-N-dimethoxyphosphinothioyl-N-methylcarbamate
CAS 28789-80-2C14H20NO5PS
(5-Methoxy-2,3-dihydrobenzofuran-2-yl)methanamine
CAS 29027-39-2C10H13NO2
(7-Methoxy-2,3-dihydro-1-benzofuran-2-yl)methanamine
CAS 62035-49-8C10H13NO2
amine chemical structure, C11H15NO2, CAS 32459-08-8](/s/NJYGDUAMSZQKFH-UHFFFAOYSA-N.svg)
[(7-Methoxy-2,3-dihydro-1-benzofuran-2-yl)methyl](methyl)amine
CAS 32459-08-8C11H15NO2
![N-[(5,7-Dichloro-2,3-dihydro-1-benzofuran-2-yl)methyl]propan-2-amine chemical structure, C12H15Cl2NO, CAS 46697-00-1](/s/FCFGRTQYVIIVRZ-UHFFFAOYSA-N.svg)
N-[(5,7-Dichloro-2,3-dihydro-1-benzofuran-2-yl)methyl]propan-2-amine
CAS 46697-00-1C12H15Cl2NO
Carbamic acid, methyl(methylthio)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
CAS 50539-80-5C13H17NO3S
Carbamic acid, (ethylthio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
CAS 50539-81-6C14H19NO3S
Carbamic acid, N-(dimethylamino)thio-N-methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester
CAS 55285-04-6C14H20N2O3S
- 27 suppliersCarbosulfan55285-14-8C20H32N2O3S
- Furofenac56983-13-2C12H14O3
- 5-Benzofuranacetic acid, 2,3-dihydro-7-chloro-alpha,2,2-trimethyl-57899-02-2C13H15ClO3
- 1-(2-Methyl-2,3-dihydro-1-benzofuran-5-yl)ethan-1-one58621-51-5C11H12O2
- N-Nitrosocarbofuran62593-23-1C12H14N2O4
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-methoxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-26-8C15H20N2O5S
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-ethoxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-27-9C16H22N2O5S
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-propoxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-28-0C17H24N2O5S
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-isopropoxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-29-1C17H24N2O5S
- Furathiocarb65907-30-4C18H26N2O5S
- 2,3-Dihydro-2,2-dimethyl-7-benzofuranyl 2,4-dimethyl-5-oxo-6-oxa-3-thia-2,4-diazaundecanoate65907-31-5C19H28N2O5S
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-heptyloxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-32-6C21H32N2O5S
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-octyloxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-33-7C22H34N2O5S
- Benzofuran, 2,3-dihydro-2,2-dimethyl-7-(N-(N-methyl-N-decyloxycarbonylaminothio)-N-methylcarbamoyloxy)-65907-34-8C24H38N2O5S
- Carbamic acid, ((hexyloxy)sulfinyl)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester77248-43-2C18H27NO5S
- Carbamic acid, ((butylthio)sulfinyl)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester77248-49-8C16H23NO4S2
- 4 suppliersBenfuracarb82560-54-1C20H30N2O5S
- 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl (ethoxysulfanyl)methylcarbamate86627-63-6C14H19NO4S
- Carbamic acid, methyl((1-methylethoxy)thio)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester86627-64-7C15H21NO4S
- Carbamic acid, ((hexyloxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester86627-65-8C18H27NO4S
- Carbamic acid, ((dodecyloxy)thio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester86627-68-1C24H39NO4S
- Carbamic acid, ((hexyloxy)dithio)methyl-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester86627-73-8C18H27NO4S2
- 2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl heptyl sulfinylbis(methylcarbamate)77248-39-6C21H32N2O6S
- Carbamic acid, ((1,1-dimethylethyl)thio)sulfinyl)methyl)-, 2,3-dihydro-2,2-dimethyl-7-benzofuranyl ester77267-55-1C16H23NO4S2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold c1ccc2[nH]ccc2c1](/scaffold/SIKJAQJRHWYJAI-UHFFFAOYSA-N/structure.svg)
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c1ccc2[nH]cnc2c11,206 chemicals![Scaffold c1ccc2[nH]ncc2c1](/scaffold/BAXOFTOLAUCFNW-UHFFFAOYSA-N/structure.svg)
c1ccc2[nH]ncc2c1795 chemicals
c1ccc2scnc2c1756 chemicals
c1ccc2occc2c1632 chemicals
c1ccc2c(c1)CCC2621 chemicals
c1ccc2c(c1)OCO2536 chemicals
c1ccc2sccc2c1529 chemicals
c1ccn2ccnc2c1525 chemicals
c1ccc2c(c1)CCN2440 chemicals![Scaffold O=c1[nH]c(=O)c2[nH]cnc2[nH]1](/scaffold/LRFVTYWOQMYALW-UHFFFAOYSA-N/structure.svg)
O=c1[nH]c(=O)c2[nH]cnc2[nH]1411 chemicals
O=C1NC(=O)c2ccccc21352 chemicals