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Murcko scaffold

4,6(1H,5H)-Pyrimidinedione scaffold

123 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
8
Chemicals
123
With full pages
16
Scaffold SMILES

O=C1CC(=O)NC=N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4,6(1H,5H)-Pyrimidinedione page
Murcko scaffold O=C1CC(=O)NC=N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 123 chemicals

Barbituric acid, 5-ethyl-2-imino-5-(3-methyl-2-butenyl)- chemical structure, C11H17N3O2, CAS 66968-46-5
Barbituric acid, 5-ethyl-2-imino-5-(3-methyl-2-butenyl)-
CAS 66968-46-5C11H17N3O2
2-O-Isopropyl barbitone chemical structure, C11H18N2O3, CAS 85445-03-0
2-O-Isopropyl barbitone
CAS 85445-03-0C11H18N2O3
4,6(1H,5H)-Pyrimidinedione, 5-bromo- chemical structure, C4H3BrN2O2, CAS 52176-13-3
4,6(1H,5H)-Pyrimidinedione, 5-bromo-
CAS 52176-13-3C4H3BrN2O2
2-Amino-5,5-diethylpyrimidine-4,6(1H,5H)-dione chemical structure, C8H13N3O2, CAS 64289-52-7
2-Amino-5,5-diethylpyrimidine-4,6(1H,5H)-dione
CAS 64289-52-7C8H13N3O2
2-Methyl-5-nitroso-1H-pyrimidine-4,6-dione chemical structure, C5H5N3O3, CAS 69228-29-1
2-Methyl-5-nitroso-1H-pyrimidine-4,6-dione
CAS 69228-29-1C5H5N3O3
2-Methyl-4,6-pyrimidinedione chemical structure, C5H6N2O2, CAS 40497-30-1
2-Methyl-4,6-pyrimidinedione
CAS 40497-30-1C5H6N2O2
2-Methoxy-1-methyl-5,5-di(2-propenyl)pyrimidine-4,6(1H,5H)-dione chemical structure, C12H16N2O3, CAS 54833-17-9
2-Methoxy-1-methyl-5,5-di(2-propenyl)pyrimidine-4,6(1H,5H)-dione
CAS 54833-17-9C12H16N2O3
5-Nitropyrimidine-4,6(1H,5H)-dione chemical structure, C4H3N3O4, CAS 63447-42-7
5-Nitropyrimidine-4,6(1H,5H)-dione
CAS 63447-42-7C4H3N3O4
4,6(1H,5H)-Pyrimidinedione chemical structure, C4H4N2O2, CAS 25286-58-2
4,6(1H,5H)-Pyrimidinedione
CAS 25286-58-2C4H4N2O2
4,6(1H,5H)-Pyrimidinedione,2-amino-5-butyl-5-ethyl- chemical structure, C10H17N3O2, CAS 485806-01-7
4,6(1H,5H)-Pyrimidinedione,2-amino-5-butyl-5-ethyl-
CAS 485806-01-7C10H17N3O2
5-(5-Ethyl-2-imino-4,6-dioxohexahydro-5-pyrimidinyl)pentanoic acid chemical structure, C11H17N3O4, CAS 60588-13-8
5-(5-Ethyl-2-imino-4,6-dioxohexahydro-5-pyrimidinyl)pentanoic acid
CAS 60588-13-8C11H17N3O4
2-(Propylthio)-4,6(1H,5H)-pyrimidinedione chemical structure, C7H10N2O2S, CAS 187666-88-2
2-(Propylthio)-4,6(1H,5H)-pyrimidinedione
CAS 187666-88-2C7H10N2O2S
2-Acetylamino-4,6-dioxo-5-methyl-pyrimidine chemical structure, C7H9N3O3, CAS 55477-36-6
2-Acetylamino-4,6-dioxo-5-methyl-pyrimidine
CAS 55477-36-6C7H9N3O3
4,6(1H,5H)-Pyrimidinedione, 2-methoxy-(9CI) chemical structure, C5H6N2O3, CAS 112977-55-6
4,6(1H,5H)-Pyrimidinedione, 2-methoxy-(9CI)
CAS 112977-55-6C5H6N2O3
2-Ethyl-1H-pyrimidine-4,6-dione chemical structure, C6H8N2O2, CAS 857411-92-8
2-Ethyl-1H-pyrimidine-4,6-dione
CAS 857411-92-8C6H8N2O2
Propallylonal sodium chemical structure, C10H12BrN2NaO3, CAS 18277-24-2
Propallylonal sodium
CAS 18277-24-2C10H12BrN2NaO3
Aprobarbital sodium chemical structure, C10H13N2NaO3, CAS 125-88-2
Aprobarbital sodium
CAS 125-88-2C10H13N2NaO3
Butalbital sodium chemical structure, C11H15N2NaO3, CAS 23554-70-3
Butalbital sodium
CAS 23554-70-3C11H15N2NaO3
Barbituric acid, 5-allyl-5-sec-butyl-, sodium salt chemical structure, C11H15N2NaO3, CAS 24396-96-1
Barbituric acid, 5-allyl-5-sec-butyl-, sodium salt
CAS 24396-96-1C11H15N2NaO3
Thiopental sodium chemical structure, C11H17N2NaO2S, CAS 71-73-8
Thiopental sodium
CAS 71-73-8C11H17N2NaO2S
Barbituric acid, 5-(2-butenyl)-5-ethyl-, sodium salt chemical structure, C10H13N2NaO3, CAS 2933-25-7
Barbituric acid, 5-(2-butenyl)-5-ethyl-, sodium salt
CAS 2933-25-7C10H13N2NaO3
Barbituric acid, 5-(sec-butyl)-5-(2-pentenyl)-, sodium salt chemical structure, C13H19N2NaO3, CAS 64058-03-3
Barbituric acid, 5-(sec-butyl)-5-(2-pentenyl)-, sodium salt
CAS 64058-03-3C13H19N2NaO3
Barbituric acid, 5-(2-butenyl)-5-butyl-, sodium salt chemical structure, C12H17N2NaO3, CAS 67049-97-2
Barbituric acid, 5-(2-butenyl)-5-butyl-, sodium salt
CAS 67049-97-2C12H17N2NaO3
Barbituric acid, 5-(2-butenyl)-5-sec-butyl-, sodium salt chemical structure, C12H17N2NaO3, CAS 67049-98-3
Barbituric acid, 5-(2-butenyl)-5-sec-butyl-, sodium salt
CAS 67049-98-3C12H17N2NaO3