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Murcko scaffold

Ring system with 3 rings and 20 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
12
With full pages
8
Scaffold SMILES

O=c1[nH]c2ccc(S(=O)(=O)Nc3ccccc3)cc2o1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2ccc(S(=O)(=O)Nc3ccccc3)cc2o1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-Methyl-2-oxo-N-phenyl-2,3-dihydro-1,3-benzoxazole-6-sulfonamide chemical structure, C14H12N2O4S, CAS 385381-86-2
3-Methyl-2-oxo-N-phenyl-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
CAS 385381-86-2C14H12N2O4S
N-(2-Bromophenyl)-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide chemical structure, C14H11BrN2O4S, CAS 380906-30-9
N-(2-Bromophenyl)-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
CAS 380906-30-9C14H11BrN2O4S
3-Methyl-N-(2-methylphenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide chemical structure, C15H14N2O4S, CAS 447411-32-7
3-Methyl-N-(2-methylphenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
CAS 447411-32-7C15H14N2O4S
N-(4-Methoxyphenyl)-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide chemical structure, C15H14N2O5S, CAS 385381-87-3
N-(4-Methoxyphenyl)-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
CAS 385381-87-3C15H14N2O5S
N-(4-Fluorophenyl)-3-methyl-2-oxo-1,3-benzoxazole-6-sulfonamide chemical structure, C14H11FN2O4S, CAS 401631-03-6
N-(4-Fluorophenyl)-3-methyl-2-oxo-1,3-benzoxazole-6-sulfonamide
CAS 401631-03-6C14H11FN2O4S
3-Methyl-N-(4-methylphenyl)-2-oxo-1,3-benzoxazole-6-sulfonamide chemical structure, C15H14N2O4S, CAS 524052-02-6
3-Methyl-N-(4-methylphenyl)-2-oxo-1,3-benzoxazole-6-sulfonamide
CAS 524052-02-6C15H14N2O4S
N,3-dimethyl-2-oxo-N-phenyl-1,3-benzoxazole-6-sulfonamide chemical structure, C15H14N2O4S, CAS 842959-33-5
N,3-dimethyl-2-oxo-N-phenyl-1,3-benzoxazole-6-sulfonamide
CAS 842959-33-5C15H14N2O4S
Butyl 6-[(4-fluorophenyl)sulfamoyl]-2-oxo-1,3-benzoxazole-3(2H)-carboxylate chemical structure, C18H17FN2O6S, CAS 4638-42-0
Butyl 6-[(4-fluorophenyl)sulfamoyl]-2-oxo-1,3-benzoxazole-3(2H)-carboxylate
CAS 4638-42-0C18H17FN2O6S
4-Methyl-3-[(3-methyl-2-oxo-1,3-benzoxazol-6-yl)sulfonylamino]benzoic acid chemical structure, C16H14N2O6S, CAS 896853-65-9
4-Methyl-3-[(3-methyl-2-oxo-1,3-benzoxazol-6-yl)sulfonylamino]benzoic acid
CAS 896853-65-9C16H14N2O6S
N-(2,3-Dimethylphenyl)-2-oxo-3H-1,3-benzoxazole-6-sulfonamide chemical structure, C15H14N2O4S, CAS 852558-14-6
N-(2,3-Dimethylphenyl)-2-oxo-3H-1,3-benzoxazole-6-sulfonamide
CAS 852558-14-6C15H14N2O4S
5-Chloro-N-[4-(cyanomethyl)phenyl]-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide chemical structure, C16H12ClN3O4S, CAS 898917-23-2
5-Chloro-N-[4-(cyanomethyl)phenyl]-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
CAS 898917-23-2C16H12ClN3O4S
N-(3,4-Dimethylphenyl)-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide chemical structure, C16H16N2O4S, CAS 901752-69-0
N-(3,4-Dimethylphenyl)-3-methyl-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
CAS 901752-69-0C16H16N2O4S