CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 23 atoms

70 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
23
Chemicals
70
With full pages
4
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc(COc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc(COc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 70 chemicals

3-({4-[(2-Chloro-4-nitrophenoxy)methyl]benzoyl}amino)benzenesulfonyl fluoride chemical structure, C20H14ClFN2O6S, CAS 30880-66-1
3-({4-[(2-Chloro-4-nitrophenoxy)methyl]benzoyl}amino)benzenesulfonyl fluoride
CAS 30880-66-1C20H14ClFN2O6S
Benzenesulfonylfluoride, 4-[[4-[(2-chloro-4-nitrophenoxy)methyl]benzoyl]amino]- chemical structure, C20H14ClFN2O6S, CAS 30880-67-2
Benzenesulfonylfluoride, 4-[[4-[(2-chloro-4-nitrophenoxy)methyl]benzoyl]amino]-
CAS 30880-67-2C20H14ClFN2O6S
N-(2,5-Dimethylphenyl)-4-[(4-methylphenoxy)methyl]benzamide chemical structure, C23H23NO2, CAS 692285-56-6
N-(2,5-Dimethylphenyl)-4-[(4-methylphenoxy)methyl]benzamide
CAS 692285-56-6C23H23NO2
4-[(4-Methylphenoxy)methyl]-N-(4-methylphenyl)benzamide chemical structure, C22H21NO2, CAS 339253-77-9
4-[(4-Methylphenoxy)methyl]-N-(4-methylphenyl)benzamide
CAS 339253-77-9C22H21NO2
N-(4-Fluorophenyl)-4-[(3-methylphenoxy)methyl]benzamide chemical structure, C21H18FNO2, CAS 692286-20-7
N-(4-Fluorophenyl)-4-[(3-methylphenoxy)methyl]benzamide
CAS 692286-20-7C21H18FNO2
4-[(4-Methylphenoxy)methyl]-N-phenylbenzamide chemical structure, C21H19NO2, CAS 339253-56-4
4-[(4-Methylphenoxy)methyl]-N-phenylbenzamide
CAS 339253-56-4C21H19NO2
N-(2,4-Dimethylphenyl)-4-[(3-methylphenoxy)methyl]benzamide chemical structure, C23H23NO2, CAS 692290-86-1
N-(2,4-Dimethylphenyl)-4-[(3-methylphenoxy)methyl]benzamide
CAS 692290-86-1C23H23NO2
N-(2-Ethylphenyl)-4-[(4-methylphenoxy)methyl]benzamide chemical structure, C23H23NO2, CAS 692290-88-3
N-(2-Ethylphenyl)-4-[(4-methylphenoxy)methyl]benzamide
CAS 692290-88-3C23H23NO2
N-(2-Methoxyphenyl)-4-[(3-methylphenoxy)methyl]benzamide chemical structure, C22H21NO3, CAS 692767-03-6
N-(2-Methoxyphenyl)-4-[(3-methylphenoxy)methyl]benzamide
CAS 692767-03-6C22H21NO3
4-[(3-Methylphenoxy)methyl]-N-(3-methylphenyl)benzamide chemical structure, C22H21NO2, CAS 692769-67-8
4-[(3-Methylphenoxy)methyl]-N-(3-methylphenyl)benzamide
CAS 692769-67-8C22H21NO2
4-[(2-Methoxyphenoxy)methyl]-N-[4-(trifluoromethoxy)phenyl]benzamide chemical structure, C22H18F3NO4, CAS 445231-03-8
4-[(2-Methoxyphenoxy)methyl]-N-[4-(trifluoromethoxy)phenyl]benzamide
CAS 445231-03-8C22H18F3NO4
4-[(4-tert-Butylphenoxy)methyl]-N-(2-methoxyphenyl)benzamide chemical structure, C25H27NO3, CAS 444908-11-6
4-[(4-tert-Butylphenoxy)methyl]-N-(2-methoxyphenyl)benzamide
CAS 444908-11-6C25H27NO3
4-[(2,4-Dichlorophenoxy)methyl]-N-(2-methoxyphenyl)benzamide chemical structure, C21H17Cl2NO3, CAS 438465-43-1
4-[(2,4-Dichlorophenoxy)methyl]-N-(2-methoxyphenyl)benzamide
CAS 438465-43-1C21H17Cl2NO3
Dimethyl 2-({4-[(4-ethylphenoxy)methyl]benzoyl}amino)terephthalate chemical structure, C26H25NO6, CAS 438528-89-3
Dimethyl 2-({4-[(4-ethylphenoxy)methyl]benzoyl}amino)terephthalate
CAS 438528-89-3C26H25NO6
4-[(4-Chlorophenoxy)methyl]-N-(2-methoxyphenyl)benzamide chemical structure, C21H18ClNO3, CAS 438529-94-3
4-[(4-Chlorophenoxy)methyl]-N-(2-methoxyphenyl)benzamide
CAS 438529-94-3C21H18ClNO3
4-[(2-Chlorophenoxy)methyl]-N-(2-fluorophenyl)benzamide chemical structure, C20H15ClFNO2, CAS 438530-88-2
4-[(2-Chlorophenoxy)methyl]-N-(2-fluorophenyl)benzamide
CAS 438530-88-2C20H15ClFNO2
Methyl 2-({4-[(4-bromophenoxy)methyl]benzoyl}amino)benzoate chemical structure, C22H18BrNO4, CAS 402719-26-0
Methyl 2-({4-[(4-bromophenoxy)methyl]benzoyl}amino)benzoate
CAS 402719-26-0C22H18BrNO4
N-[4-(Acetylamino)phenyl]-4-[(4-propylphenoxy)methyl]benzamide chemical structure, C25H26N2O3, CAS 438530-95-1
N-[4-(Acetylamino)phenyl]-4-[(4-propylphenoxy)methyl]benzamide
CAS 438530-95-1C25H26N2O3
Dimethyl 2-({4-[(4-chlorophenoxy)methyl]benzoyl}amino)terephthalate chemical structure, C24H20ClNO6, CAS 402729-19-5
Dimethyl 2-({4-[(4-chlorophenoxy)methyl]benzoyl}amino)terephthalate
CAS 402729-19-5C24H20ClNO6
N-(2-Methoxyphenyl)-4-[(2,3,5,6-tetrafluorophenoxy)methyl]benzamide chemical structure, C21H15F4NO3, CAS 438531-66-9
N-(2-Methoxyphenyl)-4-[(2,3,5,6-tetrafluorophenoxy)methyl]benzamide
CAS 438531-66-9C21H15F4NO3
4-[(4-Chlorophenoxy)methyl]-N-(2,3-dimethylphenyl)benzamide chemical structure, C22H20ClNO2, CAS 438531-68-1
4-[(4-Chlorophenoxy)methyl]-N-(2,3-dimethylphenyl)benzamide
CAS 438531-68-1C22H20ClNO2
N-(2-Fluorophenyl)-4-[(4-propylphenoxy)methyl]benzamide chemical structure, C23H22FNO2, CAS 438531-77-2
N-(2-Fluorophenyl)-4-[(4-propylphenoxy)methyl]benzamide
CAS 438531-77-2C23H22FNO2
4-[(4-Chlorophenoxy)methyl]-N-(2-chlorophenyl)benzamide chemical structure, C20H15Cl2NO2, CAS 438531-84-1
4-[(4-Chlorophenoxy)methyl]-N-(2-chlorophenyl)benzamide
CAS 438531-84-1C20H15Cl2NO2
N-(4-Acetamidophenyl)-4-[(4-tert-butylphenoxy)methyl]benzamide chemical structure, C26H28N2O3, CAS 495382-61-1
N-(4-Acetamidophenyl)-4-[(4-tert-butylphenoxy)methyl]benzamide
CAS 495382-61-1C26H28N2O3