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Murcko scaffold

4-Hydroxy-2-phenylpyridine scaffold

161 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
161
With full pages
3
Scaffold SMILES

O=c1cc[nH]c(-c2ccccc2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4-Hydroxy-2-phenylpyridine page
Murcko scaffold O=c1cc[nH]c(-c2ccccc2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 161 chemicals

Karetazan chemical structure, C15H14ClNO3, CAS 81051-65-2
Karetazan
CAS 81051-65-2C15H14ClNO3
2-Phenyl-6-methyl-3-carboethoxy-4-pyridone chemical structure, C15H15NO3, CAS 60032-45-3
2-Phenyl-6-methyl-3-carboethoxy-4-pyridone
CAS 60032-45-3C15H15NO3
2-Methyl-6-phenyl-1H-pyridin-4-one chemical structure, C12H11NO, CAS 7500-03-0
2-Methyl-6-phenyl-1H-pyridin-4-one
CAS 7500-03-0C12H11NO
4-Hydroxy-2-phenylpyridine chemical structure, C11H9NO, CAS 883107-55-9
4-Hydroxy-2-phenylpyridine
CAS 883107-55-9C11H9NO
3-Acetyl-2-methyl-6-phenyl-4(1H)-pyridinone chemical structure, C14H13NO2, CAS 10037-19-1
3-Acetyl-2-methyl-6-phenyl-4(1H)-pyridinone
CAS 10037-19-1C14H13NO2
2-(4-Chlorophenyl)-1-ethyl-6-methyl-4(1H)-pyridinone chemical structure, C14H14ClNO, CAS 866152-07-0
2-(4-Chlorophenyl)-1-ethyl-6-methyl-4(1H)-pyridinone
CAS 866152-07-0C14H14ClNO
Methyl 5-bromo-2-(4-chlorophenyl)-1-ethyl-6-methyl-4-oxo-1,4-dihydro-3-pyridinecarboxylate chemical structure, C16H15BrClNO3, CAS 866154-96-3
Methyl 5-bromo-2-(4-chlorophenyl)-1-ethyl-6-methyl-4-oxo-1,4-dihydro-3-pyridinecarboxylate
CAS 866154-96-3C16H15BrClNO3
3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester chemical structure, C14H13NO3, CAS 134653-73-9
3-Pyridinecarboxylic acid, 1,4-dihydro-4-oxo-6-phenyl-, ethyl ester
CAS 134653-73-9C14H13NO3
1-Methyl-2-phenyl-4(1H)-pyridinone chemical structure, C12H11NO, CAS 57311-22-5
1-Methyl-2-phenyl-4(1H)-pyridinone
CAS 57311-22-5C12H11NO
Ethyl 5-methyl-4-oxo-6-phenyl-1,4-dihydropyridine-3-carboxylate chemical structure, C15H15NO3, CAS 63514-28-3
Ethyl 5-methyl-4-oxo-6-phenyl-1,4-dihydropyridine-3-carboxylate
CAS 63514-28-3C15H15NO3
4-Oxo-6-phenyl-1,4-dihydropyridine-2-carboxylic acid chemical structure, C12H9NO3, CAS 78296-37-4
4-Oxo-6-phenyl-1,4-dihydropyridine-2-carboxylic acid
CAS 78296-37-4C12H9NO3
4-Hydroxy-6-phenylpyridine-2-carboxamide chemical structure, C12H10N2O2, CAS 85814-93-3
4-Hydroxy-6-phenylpyridine-2-carboxamide
CAS 85814-93-3C12H10N2O2
Ethyl 4-hydroxy-6-phenylpyridine-2-carboxylate chemical structure, C14H13NO3, CAS 1152096-35-9
Ethyl 4-hydroxy-6-phenylpyridine-2-carboxylate
CAS 1152096-35-9C14H13NO3
Ro 13-5478 chemical structure, C16H18N2O3, CAS 71575-96-7
Ro 13-5478
CAS 71575-96-7C16H18N2O3
4-Hydroxy-2-(2-methylthiophenyl)pyridine chemical structure, C12H11NOS, CAS 115768-79-1
4-Hydroxy-2-(2-methylthiophenyl)pyridine
CAS 115768-79-1C12H11NOS
2-(4-Chlorophenyl)pyridin-4(1H)-one chemical structure, C11H8ClNO, CAS 1261934-73-9
2-(4-Chlorophenyl)pyridin-4(1H)-one
CAS 1261934-73-9C11H8ClNO
2-(4-Fluorophenyl)-6-methylpyridin-4(1H)-one chemical structure, C12H10FNO, CAS 178430-08-5
2-(4-Fluorophenyl)-6-methylpyridin-4(1H)-one
CAS 178430-08-5C12H10FNO
Karetazan-potassium chemical structure, C15H13ClKNO3, CAS 81052-29-1
Karetazan-potassium
CAS 81052-29-1C15H13ClKNO3
4-Hydroxy-2-(2-methylphenyl)pyridine chemical structure, C12H11NO, CAS 1159814-27-3
4-Hydroxy-2-(2-methylphenyl)pyridine
CAS 1159814-27-3C12H11NO
4-Hydroxy-2-(3-methylphenyl)pyridine chemical structure, C12H11NO, CAS 1159814-48-8
4-Hydroxy-2-(3-methylphenyl)pyridine
CAS 1159814-48-8C12H11NO
4-Hydroxy-2-(4-methylphenyl)pyridine chemical structure, C12H11NO, CAS 1159814-51-3
4-Hydroxy-2-(4-methylphenyl)pyridine
CAS 1159814-51-3C12H11NO
2-(3-Aminophenyl)pyridin-4(1H)-one chemical structure, C11H10N2O, CAS 1261982-35-7
2-(3-Aminophenyl)pyridin-4(1H)-one
CAS 1261982-35-7C11H10N2O
2-(2-Hydroxyphenyl)pyridin-4(1H)-one chemical structure, C11H9NO2, CAS 1262011-32-4
2-(2-Hydroxyphenyl)pyridin-4(1H)-one
CAS 1262011-32-4C11H9NO2
2-(3-Hydroxyphenyl)pyridin-4(1H)-one chemical structure, C11H9NO2, CAS 1261942-82-8
2-(3-Hydroxyphenyl)pyridin-4(1H)-one
CAS 1261942-82-8C11H9NO2