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Murcko scaffold

Ring system with 3 rings and 15 atoms

12 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
12
With full pages
6
Scaffold SMILES

O=C1NC2CCC(=O)N2c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NC2CCC(=O)N2c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

1,5-Dioxo-4-propyl-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid chemical structure, C15H16N2O4, CAS 848052-91-5
1,5-Dioxo-4-propyl-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid
CAS 848052-91-5C15H16N2O4
4-(2-Methoxyethyl)-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo(1,2-a)quinazoline-3a-carboxylic acid chemical structure, C15H16N2O5, CAS 848178-45-0
4-(2-Methoxyethyl)-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo(1,2-a)quinazoline-3a-carboxylic acid
CAS 848178-45-0C15H16N2O5
1,5-Dioxo-4-(propan-2-yl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid chemical structure, C15H16N2O4, CAS 848316-28-9
1,5-Dioxo-4-(propan-2-yl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid
CAS 848316-28-9C15H16N2O4
4-Isobutyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid chemical structure, C16H18N2O4, CAS 863669-58-3
4-Isobutyl-1,5-dioxo-2,3,4,5-tetrahydropyrrolo[1,2-a]quinazoline-3a(1H)-carboxylic acid
CAS 863669-58-3C16H18N2O4
4-Butyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo(1,2-a)quinazoline-3a-carboxylic acid chemical structure, C16H18N2O4, CAS 863669-61-8
4-Butyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo(1,2-a)quinazoline-3a-carboxylic acid
CAS 863669-61-8C16H18N2O4
4-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid chemical structure, C13H12N2O4, CAS 863763-60-4
4-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid
CAS 863763-60-4C13H12N2O4
1,5-Dioxo-4-(prop-2-en-1-yl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid chemical structure, C15H14N2O4, CAS 872319-68-1
1,5-Dioxo-4-(prop-2-en-1-yl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid
CAS 872319-68-1C15H14N2O4
4-Ethyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid chemical structure, C14H14N2O4, CAS 868238-09-9
4-Ethyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazoline-3a-carboxylic acid
CAS 868238-09-9C14H14N2O4
2,3,4,5-Tetrahydro-1,5-dioxopyrrolo(1,2-a)quinazoline-3a(1H)-carboxylic acid chemical structure, C12H10N2O4, CAS 871909-89-6
2,3,4,5-Tetrahydro-1,5-dioxopyrrolo(1,2-a)quinazoline-3a(1H)-carboxylic acid
CAS 871909-89-6C12H10N2O4
2-(3a-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo(1,2-a)quinazolin-4-yl)acetic acid chemical structure, C14H14N2O4, CAS 1000933-03-8
2-(3a-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo(1,2-a)quinazolin-4-yl)acetic acid
CAS 1000933-03-8C14H14N2O4
3-{3a-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazolin-4-yl}propanoic acid chemical structure, C15H16N2O4, CAS 1049605-28-8
3-{3a-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazolin-4-yl}propanoic acid
CAS 1049605-28-8C15H16N2O4
4-{3a-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazolin-4-yl}butanoic acid chemical structure, C16H18N2O4, CAS 1049872-98-1
4-{3a-Methyl-1,5-dioxo-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinazolin-4-yl}butanoic acid
CAS 1049872-98-1C16H18N2O4