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Murcko scaffold

N-Phenyl-2-pyridone scaffold

372 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
13
Chemicals
372
With full pages
23
Scaffold SMILES

O=c1ccccn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenyl-2-pyridone page
Murcko scaffold O=c1ccccn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 372 chemicals

Amphenidone chemical structure, C11H10N2O, CAS 134-37-2
Amphenidone
CAS 134-37-2C11H10N2O
Pirfenidone chemical structure, C12H11NO, CAS 53179-13-8
Pirfenidone
CAS 53179-13-8C12H11NO
3-Pyridinecarbonitrile, 1-(4-aminophenyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxo- chemical structure, C13H11N3O2, CAS 68957-36-8
3-Pyridinecarbonitrile, 1-(4-aminophenyl)-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-
CAS 68957-36-8C13H11N3O2
2,4-Dimethyl-1-(4-nitrophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid chemical structure, C14H12N2O5, CAS 5238-17-5
2,4-Dimethyl-1-(4-nitrophenyl)-6-oxo-1,6-dihydropyridine-3-carboxylic acid
CAS 5238-17-5C14H12N2O5
N-Phenyl-2-pyridone chemical structure, C11H9NO, CAS 13131-02-7
N-Phenyl-2-pyridone
CAS 13131-02-7C11H9NO
1-(2-Methylphenyl)-2(1H)-pyridinone chemical structure, C12H11NO, CAS 54774-86-6
1-(2-Methylphenyl)-2(1H)-pyridinone
CAS 54774-86-6C12H11NO
1-(4-Fluorophenyl)-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid chemical structure, C14H12FNO3, CAS 24518-05-6
1-(4-Fluorophenyl)-4,6-dimethyl-2-oxo-1,2-dihydropyridine-3-carboxylic acid
CAS 24518-05-6C14H12FNO3
1-(2-Fluorophenyl)-4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarboxamide chemical structure, C14H13FN2O2, CAS 311791-37-4
1-(2-Fluorophenyl)-4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinecarboxamide
CAS 311791-37-4C14H13FN2O2
1,2-Dihydro-4,6-dimethyl-1-(4-methylphenyl)-2-oxo-3-pyridinecarbonitrile chemical structure, C15H14N2O, CAS 24522-51-8
1,2-Dihydro-4,6-dimethyl-1-(4-methylphenyl)-2-oxo-3-pyridinecarbonitrile
CAS 24522-51-8C15H14N2O
Methyl 1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridine-3-carboxylate chemical structure, C14H13NO4, CAS 672281-71-9
Methyl 1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridine-3-carboxylate
CAS 672281-71-9C14H13NO4
4-Amino-1-phenyl-1,2-dihydropyridin-2-one chemical structure, C11H10N2O, CAS 256653-41-5
4-Amino-1-phenyl-1,2-dihydropyridin-2-one
CAS 256653-41-5C11H10N2O
4-Amino-1-(4-chlorophenyl)pyridin-2-one chemical structure, C11H9ClN2O, CAS 256653-42-6
4-Amino-1-(4-chlorophenyl)pyridin-2-one
CAS 256653-42-6C11H9ClN2O
3-Acetyl-1-(4-methoxyphenyl)-4,6-dimethylpyridin-2(1H)-one chemical structure, C16H17NO3, CAS 53475-43-7
3-Acetyl-1-(4-methoxyphenyl)-4,6-dimethylpyridin-2(1H)-one
CAS 53475-43-7C16H17NO3
4,6-Dimethyl-1-(3-methylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile chemical structure, C15H14N2O, CAS 634173-21-0
4,6-Dimethyl-1-(3-methylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile
CAS 634173-21-0C15H14N2O
2-Hydroxy-4-methyl-1-(2-methylphenyl)-6-oxopyridine-3-carbonitrile chemical structure, C14H12N2O2, CAS 71683-89-1
2-Hydroxy-4-methyl-1-(2-methylphenyl)-6-oxopyridine-3-carbonitrile
CAS 71683-89-1C14H12N2O2
1-(2,4-Dichlorophenyl)-6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinecarbonitrile chemical structure, C14H7Cl2F3N2O, CAS 339276-98-1
1-(2,4-Dichlorophenyl)-6-methyl-2-oxo-4-(trifluoromethyl)-1,2-dihydro-3-pyridinecarbonitrile
CAS 339276-98-1C14H7Cl2F3N2O
4-Amino-1-(4-chlorophenyl)-2-oxopyridine-3-carbonitrile chemical structure, C12H8ClN3O, CAS 352553-98-1
4-Amino-1-(4-chlorophenyl)-2-oxopyridine-3-carbonitrile
CAS 352553-98-1C12H8ClN3O
3-Methyl-1-phenyl-2-(1H) pyridone chemical structure, C12H11NO, CAS 53427-93-3
3-Methyl-1-phenyl-2-(1H) pyridone
CAS 53427-93-3C12H11NO
1-(4'-Chlorophenyl)-5-methyl-2-(1H)-pyridone chemical structure, C12H10ClNO, CAS 53427-80-8
1-(4'-Chlorophenyl)-5-methyl-2-(1H)-pyridone
CAS 53427-80-8C12H10ClNO
5-Ethyl-1-phenyl-1H-pyridin-2-one chemical structure, C13H13NO, CAS 53427-98-8
5-Ethyl-1-phenyl-1H-pyridin-2-one
CAS 53427-98-8C13H13NO
2(1H)-Pyridinone, 6-methyl-1-phenyl- chemical structure, C12H11NO, CAS 13179-27-6
2(1H)-Pyridinone, 6-methyl-1-phenyl-
CAS 13179-27-6C12H11NO
2(1H)-Pyridinone, 1-(4-methoxyphenyl)-5-methyl- chemical structure, C13H13NO2, CAS 53427-77-3
2(1H)-Pyridinone, 1-(4-methoxyphenyl)-5-methyl-
CAS 53427-77-3C13H13NO2
1-(4-Nitrophenyl)-1H-pyridin-2-one chemical structure, C11H8N2O3, CAS 53427-97-7
1-(4-Nitrophenyl)-1H-pyridin-2-one
CAS 53427-97-7C11H8N2O3
4-Methyl-1-phenyl-2(1H)-Pyridinone chemical structure, C12H11NO, CAS 161057-93-8
4-Methyl-1-phenyl-2(1H)-Pyridinone
CAS 161057-93-8C12H11NO