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Murcko scaffold

Ring system with 2 rings and 14 atoms

12 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 14
Chemicals: 12
With full pages: 4

Scaffold SMILES

O=c1ccoc(CN2CCNCC2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=c1ccoc(CN2CCNCC2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-Hydroxy-6-(hydroxymethyl)-2-[(4-methylpiperazin-1-yl)methyl]pyran-4-one chemical structure, C12H18N2O4, CAS 90293-63-3

3-Hydroxy-6-(hydroxymethyl)-2-[(4-methylpiperazin-1-yl)methyl]pyran-4-one

CAS 90293-63-3C₁₂H₁₈N₂O₄

2-(4-Ethyl-piperazin-1-ylmethyl)-3-hydroxy-6-hydroxymethyl-pyran-4-one chemical structure, C13H20N2O4, CAS 325992-55-0

2-(4-Ethyl-piperazin-1-ylmethyl)-3-hydroxy-6-hydroxymethyl-pyran-4-one

CAS 325992-55-0C₁₃H₂₀N₂O₄

Ethyl 4-{[3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl]methyl}piperazine-1-carboxylate chemical structure, C14H20N2O6, CAS 315235-13-3

Ethyl 4-{[3-hydroxy-6-(hydroxymethyl)-4-oxo-4H-pyran-2-yl]methyl}piperazine-1-carboxylate

CAS 315235-13-3C₁₄H₂₀N₂O₆

3-Hydroxy-2-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-6-(hydroxymethyl)-4H-pyran-4-one chemical structure, C13H20N2O5, CAS 325992-64-1

3-Hydroxy-2-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-6-(hydroxymethyl)-4H-pyran-4-one

CAS 325992-64-1C₁₃H₂₀N₂O₅

4H-Pyran-2-carboxylic acid, 5-hydroxy-6-((4-methyl-1-piperazinyl)methyl)-4-oxo-, ethyl ester chemical structure, C14H20N2O5, CAS 66556-16-9

4H-Pyran-2-carboxylic acid, 5-hydroxy-6-((4-methyl-1-piperazinyl)methyl)-4-oxo-, ethyl ester

CAS 66556-16-9C₁₄H₂₀N₂O₅

5-Hydroxy-2-(piperazin-1-ylmethyl)-4H-pyran-4-one chemical structure, C10H14N2O3, CAS 1094466-10-0

5-Hydroxy-2-(piperazin-1-ylmethyl)-4H-pyran-4-one

CAS 1094466-10-0C₁₀H₁₄N₂O₃

5-Hydroxy-2-[(4-methylpiperazin-1-yl)methyl]pyran-4-one chemical structure, C11H16N2O3, CAS 794470-75-0

5-Hydroxy-2-[(4-methylpiperazin-1-yl)methyl]pyran-4-one

CAS 794470-75-0C₁₁H₁₆N₂O₃

5-Methoxy-2-[(piperazin-1-yl)methyl]-4H-pyran-4-one chemical structure, C11H16N2O3, CAS 1091394-36-3

5-Methoxy-2-[(piperazin-1-yl)methyl]-4H-pyran-4-one

CAS 1091394-36-3C₁₁H₁₆N₂O₃

5-Methoxy-2-(piperazin-1-ylmethyl)-4H-pyran-4-one dihydrochloride chemical structure, C11H18Cl2N2O3, CAS 1426291-35-1

5-Methoxy-2-(piperazin-1-ylmethyl)-4H-pyran-4-one dihydrochloride

CAS 1426291-35-1C₁₁H₁₈Cl₂N₂O₃

5-Hydroxy-2-(piperazin-1-ylmethyl)-4H-pyran-4-one dihydrochloride chemical structure, C10H16Cl2N2O3, CAS 1426290-68-7

5-Hydroxy-2-(piperazin-1-ylmethyl)-4H-pyran-4-one dihydrochloride

CAS 1426290-68-7C₁₀H₁₆Cl₂N₂O₃

4-[(5-Hydroxy-4-oxo-4H-pyran-2-yl)methyl]piperazine-1-carbaldehyde chemical structure, C11H14N2O4, CAS 1807982-45-1

4-[(5-Hydroxy-4-oxo-4H-pyran-2-yl)methyl]piperazine-1-carbaldehyde

CAS 1807982-45-1C₁₁H₁₄N₂O₄

4-[(5-Methoxy-4-oxopyran-2-yl)methyl]piperazine-1-sulfonyl fluoride chemical structure, C11H15FN2O5S, CAS 2361770-10-5

4-[(5-Methoxy-4-oxopyran-2-yl)methyl]piperazine-1-sulfonyl fluoride

CAS 2361770-10-5C₁₁H₁₅FN₂O₅S