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Murcko scaffold

Ring system with 4 rings and 25 atoms

28 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
28
With full pages
4
Scaffold SMILES

c1ccc(-c2cnn3c(NCCCN4CCOCC4)ccnc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cnn3c(NCCCN4CCOCC4)ccnc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

3-(4-Fluorophenyl)-2,5-dimethyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26FN5O, CAS 842111-91-5
3-(4-Fluorophenyl)-2,5-dimethyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 842111-91-5C21H26FN5O
2,5-Dimethyl-N-[3-(morpholin-4-yl)propyl]-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H27N5O, CAS 862208-22-8
2,5-Dimethyl-N-[3-(morpholin-4-yl)propyl]-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 862208-22-8C21H27N5O
5-Methyl-N-(3-morpholin-4-ylpropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H25N5O, CAS 877781-69-6
5-Methyl-N-(3-morpholin-4-ylpropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877781-69-6C20H25N5O
3-(4-Chlorophenyl)-5-methyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24ClN5O, CAS 900259-31-6
3-(4-Chlorophenyl)-5-methyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900259-31-6C20H24ClN5O
2-Methyl-N-[3-(morpholin-4-yl)propyl]-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H31N5O, CAS 896833-21-9
2-Methyl-N-[3-(morpholin-4-yl)propyl]-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896833-21-9C23H31N5O
5-(tert-Butyl)-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H31N5O, CAS 896836-39-8
5-(tert-Butyl)-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896836-39-8C23H31N5O
2-Methyl-N-[3-(morpholin-4-yl)propyl]-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H31N5O, CAS 896844-02-3
2-Methyl-N-[3-(morpholin-4-yl)propyl]-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896844-02-3C23H31N5O
5-tert-Butyl-3-(4-chlorophenyl)-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H30ClN5O, CAS 899413-09-3
5-tert-Butyl-3-(4-chlorophenyl)-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 899413-09-3C23H30ClN5O
3-(4-Chlorophenyl)-2,5-dimethyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26ClN5O, CAS 850826-13-0
3-(4-Chlorophenyl)-2,5-dimethyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 850826-13-0C21H26ClN5O
5-(tert-Butyl)-3-(4-chlorophenyl)-2-methyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H32ClN5O, CAS 850749-25-6
5-(tert-Butyl)-3-(4-chlorophenyl)-2-methyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 850749-25-6C24H32ClN5O
5-(tert-Butyl)-2-methyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H33N5O, CAS 877790-34-6
5-(tert-Butyl)-2-methyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877790-34-6C24H33N5O
5-Methyl-N-(3-morpholinopropyl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H24F3N5O, CAS 900262-93-3
5-Methyl-N-(3-morpholinopropyl)-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900262-93-3C21H24F3N5O
3-(2-Methoxyphenyl)-2,5-dimethyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H29N5O2, CAS 902303-69-9
3-(2-Methoxyphenyl)-2,5-dimethyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 902303-69-9C22H29N5O2
3-(2-Methoxyphenyl)-5-methyl-N-(3-morpholin-4-ylpropyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H27N5O2, CAS 902031-13-4
3-(2-Methoxyphenyl)-5-methyl-N-(3-morpholin-4-ylpropyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 902031-13-4C21H27N5O2
5-Methyl-3-(4-methylphenyl)-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H27N5O, CAS 900282-16-8
5-Methyl-3-(4-methylphenyl)-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900282-16-8C21H27N5O
5-Isopropyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H29N5O, CAS 900890-96-2
5-Isopropyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900890-96-2C22H29N5O
2,5-Dimethyl-3-(4-methylphenyl)-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H29N5O, CAS 900878-05-9
2,5-Dimethyl-3-(4-methylphenyl)-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900878-05-9C22H29N5O
6-Allyl-5-methyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H29N5O, CAS 902024-13-9
6-Allyl-5-methyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 902024-13-9C23H29N5O
3-(2-Chlorophenyl)-2,5-dimethyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26ClN5O, CAS 902031-46-3
3-(2-Chlorophenyl)-2,5-dimethyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 902031-46-3C21H26ClN5O
N-[3-(Morpholin-4-yl)propyl]-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H29N5O, CAS 902032-04-6
N-[3-(Morpholin-4-yl)propyl]-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 902032-04-6C22H29N5O
3-(3,4-Dimethoxyphenyl)-2,5-dimethyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H31N5O3, CAS 902010-14-4
3-(3,4-Dimethoxyphenyl)-2,5-dimethyl-N-(3-morpholinopropyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 902010-14-4C23H31N5O3
2-Ethyl-5-methyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H29N5O, CAS 900278-15-1
2-Ethyl-5-methyl-N-(3-morpholinopropyl)-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900278-15-1C22H29N5O
3-(4-Fluorophenyl)-5-methyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24FN5O, CAS 921097-72-5
3-(4-Fluorophenyl)-5-methyl-N-[3-(morpholin-4-yl)propyl]pyrazolo[1,5-a]pyrimidin-7-amine
CAS 921097-72-5C20H24FN5O
3-(4-Chlorophenyl)-5-methyl-N-[3-(morpholin-4-yl)propyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H23ClF3N5O, CAS 933020-64-5
3-(4-Chlorophenyl)-5-methyl-N-[3-(morpholin-4-yl)propyl]-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 933020-64-5C21H23ClF3N5O