CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 26 atoms

62 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
62
With full pages
4
Scaffold SMILES

O=C(CSc1ccnc2c(-c3ccccc3)cnn12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccnc2c(-c3ccccc3)cnn12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 62 chemicals

N-(3-Chlorophenyl)-2-({5-methyl-3-phenylpyrazolo[1,5-A]pyrimidin-7-YL}sulfanyl)acetamide chemical structure, C21H17ClN4OS, CAS 849920-44-1
N-(3-Chlorophenyl)-2-({5-methyl-3-phenylpyrazolo[1,5-A]pyrimidin-7-YL}sulfanyl)acetamide
CAS 849920-44-1C21H17ClN4OS
2-((2,5-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)thio)-N-phenylacetamide chemical structure, C22H20N4OS, CAS 849922-14-1
2-((2,5-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)thio)-N-phenylacetamide
CAS 849922-14-1C22H20N4OS
2-((2,5-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)thio)-N-(3-nitrophenyl)acetamide chemical structure, C22H19N5O3S, CAS 850157-31-2
2-((2,5-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)thio)-N-(3-nitrophenyl)acetamide
CAS 850157-31-2C22H19N5O3S
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(3,4-dimethylphenyl)acetamide chemical structure, C27H30N4OS, CAS 850188-01-1
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(3,4-dimethylphenyl)acetamide
CAS 850188-01-1C27H30N4OS
N-(4-Acetylphenyl)-2-({5-methyl-3-phenylpyrazolo[1,5-A]pyrimidin-7-YL}sulfanyl)acetamide chemical structure, C23H20N4O2S, CAS 850188-75-9
N-(4-Acetylphenyl)-2-({5-methyl-3-phenylpyrazolo[1,5-A]pyrimidin-7-YL}sulfanyl)acetamide
CAS 850188-75-9C23H20N4O2S
N-(3,4-Dimethylphenyl)-2-[(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide chemical structure, C24H24N4OS, CAS 850191-08-1
N-(3,4-Dimethylphenyl)-2-[(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide
CAS 850191-08-1C24H24N4OS
N-(3-Chloro-4-methylphenyl)-2-[(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide chemical structure, C23H21ClN4OS, CAS 850194-37-5
N-(3-Chloro-4-methylphenyl)-2-[(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide
CAS 850194-37-5C23H21ClN4OS
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(4-ethoxyphenyl)acetamide chemical structure, C27H29ClN4O2S, CAS 850229-67-3
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(4-ethoxyphenyl)acetamide
CAS 850229-67-3C27H29ClN4O2S
N-(4-Ethoxyphenyl)-2-({5-methyl-3-phenylpyrazolo[1,5-A]pyrimidin-7-YL}sulfanyl)acetamide chemical structure, C23H22N4O2S, CAS 850237-60-4
N-(4-Ethoxyphenyl)-2-({5-methyl-3-phenylpyrazolo[1,5-A]pyrimidin-7-YL}sulfanyl)acetamide
CAS 850237-60-4C23H22N4O2S
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(4-methylphenyl)acetamide chemical structure, C26H28N4OS, CAS 850720-43-3
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(4-methylphenyl)acetamide
CAS 850720-43-3C26H28N4OS
N-(4-Hydroxyphenyl)-2-(5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanylacetamide chemical structure, C21H18N4O2S, CAS 850721-97-0
N-(4-Hydroxyphenyl)-2-(5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanylacetamide
CAS 850721-97-0C21H18N4O2S
N-(4-Acetylphenyl)-2-{[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}acetamide chemical structure, C24H21ClN4O2S, CAS 850730-58-4
N-(4-Acetylphenyl)-2-{[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}acetamide
CAS 850730-58-4C24H21ClN4O2S
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-phenylacetamide chemical structure, C25H25ClN4OS, CAS 850738-78-2
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-phenylacetamide
CAS 850738-78-2C25H25ClN4OS
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(2-methylphenyl)acetamide chemical structure, C26H27ClN4OS, CAS 850743-31-6
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(2-methylphenyl)acetamide
CAS 850743-31-6C26H27ClN4OS
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-phenylacetamide chemical structure, C25H26N4OS, CAS 850744-66-0
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-phenylacetamide
CAS 850744-66-0C25H26N4OS
N-(3-Chloro-4-methylphenyl)-2-{[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}acetamide chemical structure, C23H20Cl2N4OS, CAS 850824-54-3
N-(3-Chloro-4-methylphenyl)-2-{[3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}acetamide
CAS 850824-54-3C23H20Cl2N4OS
2-((2,5-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)thio)-N-(4-ethoxyphenyl)acetamide chemical structure, C24H24N4O2S, CAS 850750-06-0
2-((2,5-Dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)thio)-N-(4-ethoxyphenyl)acetamide
CAS 850750-06-0C24H24N4O2S
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(3-chlorophenyl)acetamide chemical structure, C25H24Cl2N4OS, CAS 850750-83-3
2-{[5-tert-Butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(3-chlorophenyl)acetamide
CAS 850750-83-3C25H24Cl2N4OS
2-{[3-(4-Chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(4-methylphenyl)acetamide chemical structure, C23H21ClN4OS, CAS 850751-31-4
2-{[3-(4-Chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-yl]sulfanyl}-N-(4-methylphenyl)acetamide
CAS 850751-31-4C23H21ClN4OS
N-(4-Acetylphenyl)-2-(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanylacetamide chemical structure, C24H22N4O2S, CAS 850751-65-4
N-(4-Acetylphenyl)-2-(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanylacetamide
CAS 850751-65-4C24H22N4O2S
N-(4-Acetylphenyl)-2-[(5-tert-butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide chemical structure, C27H28N4O2S, CAS 850752-27-1
N-(4-Acetylphenyl)-2-[(5-tert-butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide
CAS 850752-27-1C27H28N4O2S
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide chemical structure, C26H28N4O2S, CAS 850762-87-7
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(4-methoxyphenyl)acetamide
CAS 850762-87-7C26H28N4O2S
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(3-chloro-4-methylphenyl)acetamide chemical structure, C26H27ClN4OS, CAS 850802-49-2
2-[(5-tert-Butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]-N-(3-chloro-4-methylphenyl)acetamide
CAS 850802-49-2C26H27ClN4OS
N-(3-Chlorophenyl)-2-[(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide chemical structure, C22H19ClN4OS, CAS 850802-83-4
N-(3-Chlorophenyl)-2-[(2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-yl)sulfanyl]acetamide
CAS 850802-83-4C22H19ClN4OS