Murcko scaffold
Spiro[cyclopropane-1,3'-indoline] scaffold
163 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 11
- Chemicals
- 163
- With full pages
- 2
Scaffold SMILES
c1ccc2c(c1)NCC21CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 163 chemicals
![Spiro[cyclopropane-1,3'-indoline] chemical structure, C10H11N, CAS 174-66-3](/s/HVUXNJRKIXTEJG-UHFFFAOYSA-N.svg)
Spiro[cyclopropane-1,3'-indoline]
CAS 174-66-3C10H11N
![6'-Nitro-1',2'-dihydrospiro[cyclopropane-1,3'-indole] chemical structure, C10H10N2O2, CAS 618446-19-8](/s/PCVYGMFTRVWQMZ-UHFFFAOYSA-N.svg)
6'-Nitro-1',2'-dihydrospiro[cyclopropane-1,3'-indole]
CAS 618446-19-8C10H10N2O2
![1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-yl)ethanone chemical structure, C12H14N2O, CAS 645419-13-2](/s/ZWPDDGOGZRNKKC-UHFFFAOYSA-N.svg)
1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-yl)ethanone
CAS 645419-13-2C12H14N2O
![5'-(Methylsulfonyl)spiro[cyclopropane-1,3'-indoline] chemical structure, C11H13NO2S, CAS 1263358-40-2](/s/FETRVDFEMMAZGT-UHFFFAOYSA-N.svg)
5'-(Methylsulfonyl)spiro[cyclopropane-1,3'-indoline]
CAS 1263358-40-2C11H13NO2S
![5'-Fluorospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10FN, CAS 913179-36-9](/s/HJFDQUZANMKTQT-UHFFFAOYSA-N.svg)
5'-Fluorospiro[cyclopropane-1,3'-indoline]
CAS 913179-36-9C10H10FN
![5'-Bromospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10BrN, CAS 1260763-03-8](/s/ZAXSHDQOFNHDIM-UHFFFAOYSA-N.svg)
5'-Bromospiro[cyclopropane-1,3'-indoline]
CAS 1260763-03-8C10H10BrN
![Spiro[cyclopropane-1,3'-indole]-1'(2'H)-carbonyl chloride chemical structure, C11H10ClNO, CAS 119199-52-9](/s/OYLFAYIGVMJKAH-UHFFFAOYSA-N.svg)
Spiro[cyclopropane-1,3'-indole]-1'(2'H)-carbonyl chloride
CAS 119199-52-9C11H10ClNO
![6'-Methylspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13N, CAS 1461714-59-9](/s/CJPRZRPSLJGHGO-UHFFFAOYSA-N.svg)
6'-Methylspiro[cyclopropane-1,3'-indoline]
CAS 1461714-59-9C11H13N
![6'-Bromospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10BrN, CAS 1379360-39-0](/s/KAEJBWOGMVMEAN-UHFFFAOYSA-N.svg)
6'-Bromospiro[cyclopropane-1,3'-indoline]
CAS 1379360-39-0C10H10BrN
![4'-Fluorospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10FN, CAS 1823904-39-7](/s/MGEYUTFAYKRGMG-UHFFFAOYSA-N.svg)
4'-Fluorospiro[cyclopropane-1,3'-indoline]
CAS 1823904-39-7C10H10FN
![7'-Fluorospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10FN, CAS 1461714-90-8](/s/UHRUFLKWQXZJJM-UHFFFAOYSA-N.svg)
7'-Fluorospiro[cyclopropane-1,3'-indoline]
CAS 1461714-90-8C10H10FN
![7'-Chlorospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10ClN, CAS 1505857-33-9](/s/BYMOKQDKWNZTSG-UHFFFAOYSA-N.svg)
7'-Chlorospiro[cyclopropane-1,3'-indoline]
CAS 1505857-33-9C10H10ClN
![7'-Bromospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10BrN, CAS 1694042-51-7](/s/CKYIPMDJSNLMKH-UHFFFAOYSA-N.svg)
7'-Bromospiro[cyclopropane-1,3'-indoline]
CAS 1694042-51-7C10H10BrN
![7'-Methylspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13N, CAS 1461708-50-8](/s/RCNANNFDGSYTLL-UHFFFAOYSA-N.svg)
7'-Methylspiro[cyclopropane-1,3'-indoline]
CAS 1461708-50-8C11H13N
![7'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] chemical structure, C11H10F3N, CAS 1516693-07-4](/s/CPNUMSJOCLMYRD-UHFFFAOYSA-N.svg)
7'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline]
CAS 1516693-07-4C11H10F3N
![7'-Methoxyspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13NO, CAS 1461708-60-0](/s/KGDCMLSNGMQCLD-UHFFFAOYSA-N.svg)
7'-Methoxyspiro[cyclopropane-1,3'-indoline]
CAS 1461708-60-0C11H13NO
![4'-Bromospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10BrN, CAS 1823921-08-9](/s/YSJAOQKFRFLJOO-UHFFFAOYSA-N.svg)
4'-Bromospiro[cyclopropane-1,3'-indoline]
CAS 1823921-08-9C10H10BrN
![4'-Methylspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13N, CAS 1823942-93-3](/s/QKMZOEYGZMPHTG-UHFFFAOYSA-N.svg)
4'-Methylspiro[cyclopropane-1,3'-indoline]
CAS 1823942-93-3C11H13N
![4'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] chemical structure, C11H10F3N, CAS 1823881-89-5](/s/AANQQDUYCFQKCM-UHFFFAOYSA-N.svg)
4'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline]
CAS 1823881-89-5C11H10F3N
![4'-Methoxyspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13NO, CAS 1823868-84-3](/s/MYUFPLMFHJOOLV-UHFFFAOYSA-N.svg)
4'-Methoxyspiro[cyclopropane-1,3'-indoline]
CAS 1823868-84-3C11H13NO
![5'-Chlorospiro[cyclopropane-1,3'-indoline] chemical structure, C10H10ClN, CAS 1538359-43-1](/s/MKOPQNQNAIPLBB-UHFFFAOYSA-N.svg)
5'-Chlorospiro[cyclopropane-1,3'-indoline]
CAS 1538359-43-1C10H10ClN
![5'-Methylspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13N, CAS 1461714-36-2](/s/ZDMUVJHHXFHLJV-UHFFFAOYSA-N.svg)
5'-Methylspiro[cyclopropane-1,3'-indoline]
CAS 1461714-36-2C11H13N
![5'-Methoxyspiro[cyclopropane-1,3'-indoline] chemical structure, C11H13NO, CAS 1461706-07-9](/s/FEOMQBMDJIFMLK-UHFFFAOYSA-N.svg)
5'-Methoxyspiro[cyclopropane-1,3'-indoline]
CAS 1461706-07-9C11H13NO
![5'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline] chemical structure, C11H10F3N, CAS 1211585-30-6](/s/LVUMLLFXMSVXBR-UHFFFAOYSA-N.svg)
5'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline]
CAS 1211585-30-6C11H10F3N
- Spiro[cyclopropane-1,3'-indolin]-6'-amine1823930-24-0C10H12N2
- 6'-Fluorospiro[cyclopropane-1,3'-indoline]1461713-29-0C10H10FN
- 6'-Chloro-1',2'-dihydrospiro(cyclopropane-1,3'-indole)1403899-01-3C10H10ClN
- 6'-Methoxyspiro[cyclopropane-1,3'-indoline]1523068-91-8C11H13NO
- 6'-(Trifluoromethyl)spiro[cyclopropane-1,3'-indoline]1823903-80-5C11H10F3N
- 1',2'-Dihydrospiro[cyclopropane-1,3'-indole] hydrochloride1788041-56-4C10H12ClN
- 1-(6'-Aminospiro[cyclopropane-1,3'-indolin]-1'-YL)ethanone hydrochloride873056-10-1C12H15ClN2O
- 5'-Ethyl-1',2'-dihydrospiro[cyclopropane-1,3'-indole]1500279-83-3C12H15N
- 7'-Ethyl-1',2'-dihydrospiro[cyclopropane-1,3'-indole]1521807-74-8C12H15N
- 1',2'-Dihydrospiro[cyclopropane-1,3'-indole]-5'-carboxylic acid1558464-75-7C11H11NO2
- 5'-Nitrospiro[cyclopropane-1,3'-indoline]1695617-59-4C10H10N2O2
- 7'-Nitro-1',2'-dihydrospiro[cyclopropane-1,3'-indole]1697091-16-9C10H10N2O2
- 5-(Trifluoromethoxy)spiro[1,2-dihydroindole-3,1'-cyclopropane]1690687-57-0C11H10F3NO
- 5'-(Difluoromethoxy)spiro[cyclopropane-1,3'-indoline]1695764-14-7C11H11F2NO
- Methyl spiro[cyclopropane-1,3'-indoline]-6'-carboxylate1860865-59-3C12H13NO2
- 5'-Fluoro-1',2'-dihydrospiro[cyclopropane-1,3'-indole] hydrochloride2197061-90-6C10H11ClFN
- 6'-Fluorospiro[cyclopropane-1,3'-indoline] hydrochloride2197055-61-9C10H11ClFN
- 5'-Bromo-1',2'-dihydrospiro[cyclopropane-1,3'-indole] hydrochloride2197053-32-8C10H11BrClN
- 6'-Chloro-1',2'-dihydrospiro[cyclopropane-1,3'-indole] hydrochloride2197054-82-1C10H11Cl2N
- 5'-(Trifluoromethyl)-1',2'-dihydrospiro[cyclopropane-1,3'-indole]hydrochloride2197055-28-8C11H11ClF3N
- 4'-Fluorospiro[cyclopropane-1,3'-indoline] hydrochloride2197054-19-4C10H11ClFN
- 4'-Chlorospiro[cyclopropane-1,3'-indoline] hydrochloride2197055-30-2C10H11Cl2N
- 5'-Chloro-1',2'-dihydrospiro[cyclopropane-1,3'-indole] hydrochloride2197057-06-8C10H11Cl2N
- 4'-Bromospiro[cyclopropane-1,3'-indoline] hydrochloride2197056-47-4C10H11BrClN
Related scaffolds
Same ring framework with different atoms or bond orders
