CompoundList
Murcko scaffold

Sulfolane scaffold

1,611 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
7
Chemicals
1,611
With full pages
162
Scaffold SMILES

O=S1(=O)CCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Murcko scaffold O=S1(=O)CCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 1,611 chemicals

3,4-Dichlorosulfolane chemical structure, C4H6Cl2O2S, CAS 3001-57-8
3,4-Dichlorosulfolane
CAS 3001-57-8C4H6Cl2O2S
3-Thiophenamine, tetrahydro-, 1,1-dioxide chemical structure, C4H9NO2S, CAS 6338-70-1
3-Thiophenamine, tetrahydro-, 1,1-dioxide
CAS 6338-70-1C4H9NO2S
3-(N-Nitrosomethylamino)sulfolan chemical structure, C5H10N2O3S, CAS 13256-21-8
3-(N-Nitrosomethylamino)sulfolan
CAS 13256-21-8C5H10N2O3S
Sulfolane chemical structure, C4H8O2S, CAS 126-33-0
Sulfolane
CAS 126-33-0C4H8O2S
2,4-Dimethylsulfolane chemical structure, C6H12O2S, CAS 1003-78-7
2,4-Dimethylsulfolane
CAS 1003-78-7C6H12O2S
3,3,4,4-Tetrachlorotetrahydrothiophene 1,1-dioxide chemical structure, C4H4Cl4O2S, CAS 3737-41-5
3,3,4,4-Tetrachlorotetrahydrothiophene 1,1-dioxide
CAS 3737-41-5C4H4Cl4O2S
3-Methylsulfolane chemical structure, C5H10O2S, CAS 872-93-5
3-Methylsulfolane
CAS 872-93-5C5H10O2S
3,4-Dihydroxysulfolane chemical structure, C4H8O4S, CAS 33967-48-5
3,4-Dihydroxysulfolane
CAS 33967-48-5C4H8O4S
Thiophene, 3,4-dibromotetrahydro-, 1,1-dioxide chemical structure, C4H6Br2O2S, CAS 15091-30-2
Thiophene, 3,4-dibromotetrahydro-, 1,1-dioxide
CAS 15091-30-2C4H6Br2O2S
Thiophene, 3-(decyloxy)tetrahydro-, 1,1-dioxide chemical structure, C14H28O3S, CAS 18760-44-6
Thiophene, 3-(decyloxy)tetrahydro-, 1,1-dioxide
CAS 18760-44-6C14H28O3S
Thiophene, 4-bromo-2,3-dichlorotetrahydro-, 1,1-dioxide chemical structure, C4H5BrCl2O2S, CAS 65243-01-8
Thiophene, 4-bromo-2,3-dichlorotetrahydro-, 1,1-dioxide
CAS 65243-01-8C4H5BrCl2O2S
3-Bromotetrahydrothiophene 1,1-dioxide chemical structure, C4H7BrO2S, CAS 14008-53-8
3-Bromotetrahydrothiophene 1,1-dioxide
CAS 14008-53-8C4H7BrO2S
Thiophene-3-ol, 4-chlorotetrahydro-, 1,1-dioxide chemical structure, C4H7ClO3S, CAS 49592-61-2
Thiophene-3-ol, 4-chlorotetrahydro-, 1,1-dioxide
CAS 49592-61-2C4H7ClO3S
3-Hydroxysulfolane chemical structure, C4H8O3S, CAS 13031-76-0
3-Hydroxysulfolane
CAS 13031-76-0C4H8O3S
Urea, 1-(2-chloroethyl)-1-nitroso-3-(tetrahydro-3-thienyl)-, S,S-dioxide chemical structure, C7H12ClN3O4S, CAS 33022-00-3
Urea, 1-(2-chloroethyl)-1-nitroso-3-(tetrahydro-3-thienyl)-, S,S-dioxide
CAS 33022-00-3C7H12ClN3O4S
(Tetrahydro-3-thienyl)hydrazine S,S-dioxide chemical structure, C4H10N2O2S, CAS 3448-12-2
(Tetrahydro-3-thienyl)hydrazine S,S-dioxide
CAS 3448-12-2C4H10N2O2S
Phosphorothioic acid, S-(4-chlorotetrahydro-3-thienyl) O,O-diethyl ester, 1,1-dioxide chemical structure, C8H16ClO5PS2, CAS 4915-25-7
Phosphorothioic acid, S-(4-chlorotetrahydro-3-thienyl) O,O-diethyl ester, 1,1-dioxide
CAS 4915-25-7C8H16ClO5PS2
Phosphonic acid, P,P'-[[(tetrahydro-1,1-dioxido-3-thienyl)imino]bis(methylene)]bis- chemical structure, C6H15NO8P2S, CAS 68992-07-4
Phosphonic acid, P,P'-[[(tetrahydro-1,1-dioxido-3-thienyl)imino]bis(methylene)]bis-
CAS 68992-07-4C6H15NO8P2S
Thiophene, 2,3-dichlorotetrahydro-, 1,1-dioxide chemical structure, C4H6Cl2O2S, CAS 51275-92-4
Thiophene, 2,3-dichlorotetrahydro-, 1,1-dioxide
CAS 51275-92-4C4H6Cl2O2S
3-Chloro-tetrahydro-thiophene 1,1-dioxide chemical structure, C4H7ClO2S, CAS 3844-04-0
3-Chloro-tetrahydro-thiophene 1,1-dioxide
CAS 3844-04-0C4H7ClO2S
2-(1,1-Dioxidotetrahydro-3-thienyl)ethanamine chemical structure, C6H13NO2S, CAS 790594-67-1
2-(1,1-Dioxidotetrahydro-3-thienyl)ethanamine
CAS 790594-67-1C6H13NO2S
3-(1-Nitropropyl)-1lambda~6~-thiolane-1,1-dione chemical structure, C7H13NO4S, CAS 17153-27-4
3-(1-Nitropropyl)-1lambda~6~-thiolane-1,1-dione
CAS 17153-27-4C7H13NO4S
3-Iodotetrahydrothiophene 1,1-dioxide chemical structure, C4H7IO2S, CAS 17236-22-5
3-Iodotetrahydrothiophene 1,1-dioxide
CAS 17236-22-5C4H7IO2S
3-Hydroxy-4-methoxy-1lambda~6~-thiolane-1,1-dione chemical structure, C5H10O4S, CAS 20627-70-7
3-Hydroxy-4-methoxy-1lambda~6~-thiolane-1,1-dione
CAS 20627-70-7C5H10O4S