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Murcko scaffold

Ring system with 3 rings and 14 atoms

224 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
224
With full pages
32
Scaffold SMILES

c1ccc(-n2cc3c(n2)CSC3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-n2cc3c(n2)CSC3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 224 chemicals

N-[2-(3-Chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C13H12ClN3OS, CAS 450340-39-3
N-[2-(3-Chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 450340-39-3C13H12ClN3OS
2-Phenyl-2,6-dihydro-4H-thieno(3,4-c)pyrazol-3-ylamine chemical structure, C11H11N3S, CAS 95469-88-8
2-Phenyl-2,6-dihydro-4H-thieno(3,4-c)pyrazol-3-ylamine
CAS 95469-88-8C11H11N3S
2-(4-Methoxy-phenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-ylamine chemical structure, C12H13N3OS, CAS 214542-49-1
2-(4-Methoxy-phenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-ylamine
CAS 214542-49-1C12H13N3OS
2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C13H15N3S, CAS 887200-91-1
2-(2,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 887200-91-1C13H15N3S
2-(2-Methylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C12H13N3S, CAS 887200-93-3
2-(2-Methylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 887200-93-3C12H13N3S
2-(3-Methylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C12H13N3S, CAS 887200-95-5
2-(3-Methylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 887200-95-5C12H13N3S
2-(4-Methylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C12H13N3S, CAS 858668-62-9
2-(4-Methylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 858668-62-9C12H13N3S
2-(4-Chlorophenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C11H10ClN3S, CAS 214542-52-6
2-(4-Chlorophenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 214542-52-6C11H10ClN3S
2-(3-Chlorophenyl)-2H,4H,6H-thieno(3,4-c)pyrazol-3-amine chemical structure, C11H10ClN3S, CAS 214542-51-5
2-(3-Chlorophenyl)-2H,4H,6H-thieno(3,4-c)pyrazol-3-amine
CAS 214542-51-5C11H10ClN3S
2-(4-Fluorophenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C11H10FN3S, CAS 865546-43-6
2-(4-Fluorophenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 865546-43-6C11H10FN3S
2-(3,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine chemical structure, C13H15N3S, CAS 887201-44-7
2-(3,4-Dimethylphenyl)-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-amine
CAS 887201-44-7C13H15N3S
N-[2-(2-Methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C15H17N3OS, CAS 396723-23-2
N-[2-(2-Methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 396723-23-2C15H17N3OS
N-[2-(2,4-Dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C16H19N3OS, CAS 396723-27-6
N-[2-(2,4-Dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 396723-27-6C16H19N3OS
N-[2-(2,4-Dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C17H21N3OS, CAS 396723-34-5
N-[2-(2,4-Dimethylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 396723-34-5C17H21N3OS
2-Ethyl-N-[2-(3-methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C18H23N3OS, CAS 392289-02-0
2-Ethyl-N-[2-(3-methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 392289-02-0C18H23N3OS
N-(2-(4-Chlorophenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C15H16ClN3OS, CAS 392252-85-6
N-(2-(4-Chlorophenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 392252-85-6C15H16ClN3OS
N-[2-(4-Fluorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C15H16FN3OS, CAS 450342-63-9
N-[2-(4-Fluorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 450342-63-9C15H16FN3OS
3-Chloro-N-[2-(3-methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C15H16ClN3OS, CAS 391866-45-8
3-Chloro-N-[2-(3-methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 391866-45-8C15H16ClN3OS
N-[2-(4-Chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-ethylbutanamide chemical structure, C17H20ClN3OS, CAS 361477-44-3
N-[2-(4-Chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-ethylbutanamide
CAS 361477-44-3C17H20ClN3OS
N-[2-(4-Methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C14H15N3OS, CAS 396723-15-2
N-[2-(4-Methylphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 396723-15-2C14H15N3OS
N-(2-(3,5-Dimethylphenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C17H21N3OS, CAS 396723-41-4
N-(2-(3,5-Dimethylphenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 396723-41-4C17H21N3OS
N-(2-(m-Tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide chemical structure, C17H21N3OS, CAS 392288-56-1
N-(2-(m-Tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide
CAS 392288-56-1C17H21N3OS
N-(2-(4-Chlorophenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide chemical structure, C16H18ClN3OS, CAS 392252-88-9
N-(2-(4-Chlorophenyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide
CAS 392252-88-9C16H18ClN3OS
3-Chloro-N-[2-(4-methoxyphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C15H16ClN3O2S, CAS 391866-54-9
3-Chloro-N-[2-(4-methoxyphenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 391866-54-9C15H16ClN3O2S