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Murcko scaffold

Ring system with 3 rings and 15 atoms

40 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
40
With full pages
9
Scaffold SMILES

O=S1Cc2cn(-c3ccccc3)nc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S1Cc2cn(-c3ccccc3)nc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

3-Methyl-N-(5-oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butanamide chemical structure, C17H21N3O2S, CAS 958586-98-6
3-Methyl-N-(5-oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butanamide
CAS 958586-98-6C17H21N3O2S
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3-methylbutanamide chemical structure, C16H18FN3O2S, CAS 1020453-09-1
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3-methylbutanamide
CAS 1020453-09-1C16H18FN3O2S
N-[2-(4-Methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3-methylbutanamide chemical structure, C17H21N3O3S, CAS 1020453-11-5
N-[2-(4-Methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-3-methylbutanamide
CAS 1020453-11-5C17H21N3O3S
3-Methyl-N-[2-(2-methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C17H21N3O2S, CAS 957298-71-4
3-Methyl-N-[2-(2-methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 957298-71-4C17H21N3O2S
N-[2-(4-Methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C14H15N3O2S, CAS 958587-18-3
N-[2-(4-Methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 958587-18-3C14H15N3O2S
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C13H12FN3O2S, CAS 958587-00-3
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 958587-00-3C13H12FN3O2S
N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C14H15N3O3S, CAS 957298-65-6
N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 957298-65-6C14H15N3O3S
N-[2-(2,3-Dimethylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C15H17N3O2S, CAS 958587-01-4
N-[2-(2,3-Dimethylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 958587-01-4C15H17N3O2S
N-(5-Oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide chemical structure, C15H17N3O2S, CAS 957298-72-5
N-(5-Oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide
CAS 957298-72-5C15H17N3O2S
N-(2-(3-Chlorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide chemical structure, C14H14ClN3O2S, CAS 1020453-15-9
N-(2-(3-Chlorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide
CAS 1020453-15-9C14H14ClN3O2S
N-[2-(4-Methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C15H17N3O3S, CAS 958843-12-4
N-[2-(4-Methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 958843-12-4C15H17N3O3S
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide chemical structure, C16H19N3O2S, CAS 1007193-20-5
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide
CAS 1007193-20-5C16H19N3O2S
N-(5-Oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C16H19N3O2S, CAS 1019099-89-8
N-(5-Oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 1019099-89-8C16H19N3O2S
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C17H21N3O2S, CAS 958587-05-8
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 958587-05-8C17H21N3O2S
N-(5-Oxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C16H19N3O2S, CAS 1019099-90-1
N-(5-Oxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 1019099-90-1C16H19N3O2S
N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide chemical structure, C17H21N3O3S, CAS 1007192-44-0
N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide
CAS 1007192-44-0C17H21N3O3S
N-[2-(4-Methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C16H19N3O2S, CAS 958587-07-0
N-[2-(4-Methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 958587-07-0C16H19N3O2S
N-(2-(4-Fluorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butyramide chemical structure, C15H16FN3O2S, CAS 958587-23-0
N-(2-(4-Fluorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butyramide
CAS 958587-23-0C15H16FN3O2S
N-[2-(4-Methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C16H19N3O3S, CAS 958843-11-3
N-[2-(4-Methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 958843-11-3C16H19N3O3S
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butyramide chemical structure, C17H21N3O2S, CAS 958587-08-1
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butyramide
CAS 958587-08-1C17H21N3O2S
2-Ethyl-N-[2-(4-methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C18H23N3O2S, CAS 958587-10-5
2-Ethyl-N-[2-(4-methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 958587-10-5C18H23N3O2S
2-Ethyl-N-(5-oxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butanamide chemical structure, C18H23N3O2S, CAS 1019099-93-4
2-Ethyl-N-(5-oxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)butanamide
CAS 1019099-93-4C18H23N3O2S
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]pentanamide chemical structure, C16H18FN3O2S, CAS 1009708-06-8
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]pentanamide
CAS 1009708-06-8C16H18FN3O2S
N-[2-(3-Chlorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-ethylbutanamide chemical structure, C17H20ClN3O2S, CAS 958587-41-2
N-[2-(3-Chlorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-ethylbutanamide
CAS 958587-41-2C17H20ClN3O2S