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Murcko scaffold

Ring system with 3 rings and 16 atoms

150 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
150
With full pages
13
Scaffold SMILES

O=S1(=O)Cc2cn(-c3ccccc3)nc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S1(=O)Cc2cn(-c3ccccc3)nc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 150 chemicals

N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-3-methylbutanamide chemical structure, C16H19N3O3S, CAS 681265-33-8
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-3-methylbutanamide
CAS 681265-33-8C16H19N3O3S
N-(2-(3,4-Dimethylphenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C15H17N3O3S, CAS 681267-12-9
N-(2-(3,4-Dimethylphenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 681267-12-9C15H17N3O3S
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pentanamide chemical structure, C16H19N3O3S, CAS 681265-29-2
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pentanamide
CAS 681265-29-2C16H19N3O3S
N-(2-(3-Chlorophenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C13H12ClN3O3S, CAS 449788-56-1
N-(2-(3-Chlorophenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 449788-56-1C13H12ClN3O3S
N-[2-(3-Chlorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C14H14ClN3O3S, CAS 449788-59-4
N-[2-(3-Chlorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 449788-59-4C14H14ClN3O3S
N-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C13H13N3O3S, CAS 214542-64-0
N-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)acetamide
CAS 214542-64-0C13H13N3O3S
N-[2-(4-Methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C15H17N3O3S, CAS 449786-72-5
N-[2-(4-Methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 449786-72-5C15H17N3O3S
3-Methyl-N-[2-(4-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C17H21N3O3S, CAS 449786-84-9
3-Methyl-N-[2-(4-methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 449786-84-9C17H21N3O3S
N-(2-(3,4-Dimethylphenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C17H21N3O3S, CAS 681267-16-3
N-(2-(3,4-Dimethylphenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 681267-16-3C17H21N3O3S
N-[2-(3,4-Dimethylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C17H21N3O3S, CAS 681267-14-1
N-[2-(3,4-Dimethylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 681267-14-1C17H21N3O3S
N-(5,5-Dioxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C16H19N3O3S, CAS 449786-78-1
N-(5,5-Dioxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 449786-78-1C16H19N3O3S
N-[2-(4-Fluorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]pentanamide chemical structure, C16H18FN3O3S, CAS 450336-68-2
N-[2-(4-Fluorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]pentanamide
CAS 450336-68-2C16H18FN3O3S
N-(2-(4-Fluorophenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide chemical structure, C16H18FN3O3S, CAS 450336-70-6
N-(2-(4-Fluorophenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide
CAS 450336-70-6C16H18FN3O3S
2-Ethyl-N-[2-(4-fluorophenyl)-5,5-dioxido-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C17H20FN3O3S, CAS 450336-71-7
2-Ethyl-N-[2-(4-fluorophenyl)-5,5-dioxido-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl]butanamide
CAS 450336-71-7C17H20FN3O3S
N-(2-(4-Fluorophenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-3-methylbutanamide chemical structure, C16H18FN3O3S, CAS 450336-72-8
N-(2-(4-Fluorophenyl)-5,5-dioxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-3-methylbutanamide
CAS 450336-72-8C16H18FN3O3S
N-[2-(3-Chlorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C15H16ClN3O3S, CAS 449788-62-9
N-[2-(3-Chlorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 449788-62-9C15H16ClN3O3S
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide chemical structure, C14H15N3O3S, CAS 681265-27-0
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)propionamide
CAS 681265-27-0C14H15N3O3S
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide chemical structure, C15H17N3O3S, CAS 681265-30-5
N-(5,5-Dioxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)isobutyramide
CAS 681265-30-5C15H17N3O3S
N-[2-(3-Chlorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-ethylbutanamide chemical structure, C17H20ClN3O3S, CAS 449788-75-4
N-[2-(3-Chlorophenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-ethylbutanamide
CAS 449788-75-4C17H20ClN3O3S
N-(5,5-Dioxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide chemical structure, C17H21N3O3S, CAS 449786-80-5
N-(5,5-Dioxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)pivalamide
CAS 449786-80-5C17H21N3O3S
N-[2-(2-Methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide chemical structure, C16H19N3O3S, CAS 449785-03-9
N-[2-(2-Methylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]butanamide
CAS 449785-03-9C16H19N3O3S
N-[2-(2,3-Dimethylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide chemical structure, C16H19N3O3S, CAS 450338-41-7
N-[2-(2,3-Dimethylphenyl)-5,5-dioxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide
CAS 450338-41-7C16H19N3O3S
N'-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)-N-propyloxamide chemical structure, C16H18N4O4S, CAS 899988-95-5
N'-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)-N-propyloxamide
CAS 899988-95-5C16H18N4O4S
N'-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)-N-(2-methylpropyl)oxamide chemical structure, C17H20N4O4S, CAS 946227-39-0
N'-(5,5-Dioxo-2-phenyl-4,6-dihydrothieno[3,4-c]pyrazol-3-yl)-N-(2-methylpropyl)oxamide
CAS 946227-39-0C17H20N4O4S