CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 16 atoms

66 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
66
With full pages
8
Scaffold SMILES

O=C(Nc1cnc[nH]c1=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cnc[nH]c1=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

N-(6-Oxo-4-sulfanyl-1,6-dihydropyrimidin-5-yl)benzamide chemical structure, C11H9N3O2S, CAS 544705-51-3
N-(6-Oxo-4-sulfanyl-1,6-dihydropyrimidin-5-yl)benzamide
CAS 544705-51-3C11H9N3O2S
4-Chloro-3-cyano-N-(6-oxo-1,6-dihydropyrimidin-5-yl)benzamide chemical structure, C12H7ClN4O2, CAS 918880-71-4
4-Chloro-3-cyano-N-(6-oxo-1,6-dihydropyrimidin-5-yl)benzamide
CAS 918880-71-4C12H7ClN4O2
N-(4-Amino-6-oxo-2-(prop-2-yn-1-ylthio)-1,6-dihydropyrimidin-5-yl)-2-methyl-3-nitrobenzamide chemical structure, C15H13N5O4S, CAS 888444-29-9
N-(4-Amino-6-oxo-2-(prop-2-yn-1-ylthio)-1,6-dihydropyrimidin-5-yl)-2-methyl-3-nitrobenzamide
CAS 888444-29-9C15H13N5O4S
N-(4-Amino-2-((2-(diethylamino)ethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-2-methyl-3-nitrobenzamide chemical structure, C18H24N6O4S, CAS 888420-39-1
N-(4-Amino-2-((2-(diethylamino)ethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-2-methyl-3-nitrobenzamide
CAS 888420-39-1C18H24N6O4S
N-(4-Amino-2-(butylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide chemical structure, C17H22N4O4S, CAS 868226-81-7
N-(4-Amino-2-(butylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide
CAS 868226-81-7C17H22N4O4S
N-(4-Amino-2-(ethylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide chemical structure, C15H18N4O4S, CAS 868226-79-3
N-(4-Amino-2-(ethylthio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide
CAS 868226-79-3C15H18N4O4S
4-Amino-N-(2-amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)benzamide chemical structure, C12H13N5O2, CAS 56742-07-5
4-Amino-N-(2-amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)benzamide
CAS 56742-07-5C12H13N5O2
Ethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate chemical structure, C19H24N4O6S, CAS 868228-31-3
Ethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate
CAS 868228-31-3C19H24N4O6S
N-(4-Amino-2-((2,4-dioxopentan-3-yl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide chemical structure, C18H20N4O6S, CAS 868228-37-9
N-(4-Amino-2-((2,4-dioxopentan-3-yl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide
CAS 868228-37-9C18H20N4O6S
Ethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate chemical structure, C17H20N4O6S, CAS 868228-29-9
Ethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate
CAS 868228-29-9C17H20N4O6S
Methyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate chemical structure, C18H22N4O6S, CAS 868228-32-4
Methyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)butanoate
CAS 868228-32-4C18H22N4O6S
N-(2-(Allylthio)-4-amino-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide chemical structure, C16H18N4O4S, CAS 868226-82-8
N-(2-(Allylthio)-4-amino-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide
CAS 868226-82-8C16H18N4O4S
Methyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate chemical structure, C16H18N4O6S, CAS 868228-28-8
Methyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)acetate
CAS 868228-28-8C16H18N4O6S
N-(2-Amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)-4-azidobenzamide chemical structure, C12H11N7O2, CAS 56742-23-5
N-(2-Amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)-4-azidobenzamide
CAS 56742-23-5C12H11N7O2
2-Amino-N-(2-amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)benzamide chemical structure, C12H13N5O2, CAS 56742-11-1
2-Amino-N-(2-amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)benzamide
CAS 56742-11-1C12H13N5O2
N-(2-Amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)-4-nitrobenzamide chemical structure, C12H11N5O4, CAS 56742-04-2
N-(2-Amino-4-methyl-6-oxo-1H-pyrimidin-5-yl)-4-nitrobenzamide
CAS 56742-04-2C12H11N5O4
N-(2-Amino-6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)-2-nitrobenzamide chemical structure, C12H11N5O4, CAS 56742-03-1
N-(2-Amino-6-methyl-4-oxo-1,4-dihydropyrimidin-5-yl)-2-nitrobenzamide
CAS 56742-03-1C12H11N5O4
Diethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)malonate chemical structure, C20H24N4O8S, CAS 868228-35-7
Diethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)malonate
CAS 868228-35-7C20H24N4O8S
N-(4-Amino-6-oxo-1,6-dihydro-5-pyrimidinyl)-4-methoxybenzamide chemical structure, C12H12N4O3, CAS 887572-16-9
N-(4-Amino-6-oxo-1,6-dihydro-5-pyrimidinyl)-4-methoxybenzamide
CAS 887572-16-9C12H12N4O3
N-(4-Amino-6-oxo-2-(propylthio)-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide chemical structure, C16H20N4O4S, CAS 868226-80-6
N-(4-Amino-6-oxo-2-(propylthio)-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide
CAS 868226-80-6C16H20N4O4S
Ethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoate chemical structure, C18H22N4O6S, CAS 868228-30-2
Ethyl 2-((4-amino-5-(3,4-dimethoxybenzamido)-6-oxo-1,6-dihydropyrimidin-2-yl)thio)propanoate
CAS 868228-30-2C18H22N4O6S
N-(4-Amino-2-((2-amino-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide chemical structure, C15H17N5O5S, CAS 868226-91-9
N-(4-Amino-2-((2-amino-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-3,4-dimethoxybenzamide
CAS 868226-91-9C15H17N5O5S
N-(2,4-Dimethyl-6-oxo-1,6-dihydropyrimidin-5-yl)-4-methylbenzamide chemical structure, C14H15N3O2, CAS 773834-81-4
N-(2,4-Dimethyl-6-oxo-1,6-dihydropyrimidin-5-yl)-4-methylbenzamide
CAS 773834-81-4C14H15N3O2
N-(4-Amino-2-((2-((2-methoxyethyl)amino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-2-fluorobenzamide chemical structure, C16H18FN5O4S, CAS 872597-19-8
N-(4-Amino-2-((2-((2-methoxyethyl)amino)-2-oxoethyl)thio)-6-oxo-1,6-dihydropyrimidin-5-yl)-2-fluorobenzamide
CAS 872597-19-8C16H18FN5O4S