Murcko scaffold
Ring system with 4 rings and 19 atoms
22 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 19
- Chemicals
- 22
- With full pages
- 4
Scaffold SMILES
O=C1CCC2C(CCC3C4CCC(=O)C4CCC23)C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 22 of 22 chemicals
Dihydroandrostenedione
CAS 846-46-8C19H28O2
2alpha-Methyl-5alpha-androstane-3,17-dione
CAS 5470-27-9C20H30O2
Androstane-3,17-dione, (5beta)-
CAS 1229-12-5C19H28O2
(2alpha,5alpha)-2-Methylandrostane-3,17-dione
C20H30O2
Androstane-3,17-dione
CAS 5982-99-0C19H28O2
Estrane-3,17-dione
CAS 5696-58-2C18H26O2
5beta,14beta-Androstane-3,17-dione
CAS 2943-09-1C19H28O2
5alpha,14beta-Androstane-3,17-dione
CAS 2942-88-3C19H28O2
1alpha-Methyl-5alpha-androstane-3,17-dione
CAS 1423-99-0C20H30O2
5Alpha-Estran-3, 17-dione
CAS 85249-09-8C18H26O2
(5Alpha)-Estrane-3,17-dione-d6
CAS 122605-91-8C18H26O2
5beta-Androstan-11alpha-ol-3,17-dione
CAS 32694-33-0C19H28O3
Formestaqne
CAS 848-35-1C19H28O3
![(5R,8R,9R,10S,13S,14S)-13-Methyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-dione chemical structure, C18H26O2, CAS 5696-51-5](/s/CRDKSBHJIGNEOH-ARAASWILSA-N.svg)
(5R,8R,9R,10S,13S,14S)-13-Methyl-1,2,4,5,6,7,8,9,10,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-3,17-dione
CAS 5696-51-5C18H26O2
![(5R,8S,9R,10S,13S,14S)-9-Hydroxy-10,13-dimethyltetradecahydro-3H-cyclopenta[A]phenanthrene-3,17(2H)-dione chemical structure, C19H28O3, CAS 1093397-61-5](/s/KNXDOCXJEBSUCI-CMKBOJANSA-N.svg)
(5R,8S,9R,10S,13S,14S)-9-Hydroxy-10,13-dimethyltetradecahydro-3H-cyclopenta[A]phenanthrene-3,17(2H)-dione
CAS 1093397-61-5C19H28O3
Adrenosterone-M
CAS 599-11-1C19H28O3
(5beta,11beta)-11-Hydroxy-androstane-3,17-dione
CAS 32694-35-2C19H28O3
![(2R,5S,8S,9S,10S,13S,14S)-2,10,13-Trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione chemical structure, C20H30O2](/s/RVSSFXUENQNQJK-NPTBFVFBSA-N.svg)
(2R,5S,8S,9S,10S,13S,14S)-2,10,13-Trimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
C20H30O2
![(5S,8S,9R,10S,13S,14S)-9-Hydroxy-10,13-dimethyldodecahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,4H)-dione chemical structure, C19H28O3, CAS 25846-32-6](/s/KNXDOCXJEBSUCI-XVGHKODSSA-N.svg)
(5S,8S,9R,10S,13S,14S)-9-Hydroxy-10,13-dimethyldodecahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,4H)-dione
CAS 25846-32-6C19H28O3
14-Hydroxyandrostane-3,17-dione
CAS 94991-81-8C19H28O3
5?-Androstanedione-13C3
CAS 2483735-09-5C19H28O2
Levonorgestrel impurity 38
CAS 2762739-32-0C20H30O3
Related scaffolds
Same ring framework with different atoms or bond orders
C1CCC2C(C1)CCC1C3CCCC3CCC21315 chemicals
O=C1C=C2CCC3C4CCCC4CCC3C2CC1301 chemicals
C1=C2CCCCC2C2CCC3CCCC3C2C1193 chemicals
O=C1C=CC2C(=C1)CCC1C3CCCC3CCC21183 chemicals
c1ccc2c(c1)CCC1C2CCC2CCCC21143 chemicals
O=C1CCC2C(CCC3C4CCCC4CCC23)C153 chemicals
O=C1CCC2C1CCC1c3ccccc3CCC1239 chemicals
C1CCC2C3=C(CCC2C1)C1CCCC1CC338 chemicals
O=C1CCC2C1CCC1C3CCCCC3CCC2132 chemicals
O=C1CCC2C1CCC1C3CCCCC3=CCC2130 chemicals
O=C1C=C2CCC3C4CCC(=O)C4CCC3C2CC129 chemicals
C1=C2C3CCCC3CCC2C2CCCCC2C125 chemicals