CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
6
With full pages
2
Scaffold SMILES

c1ccc(-c2ccnc(N3CCCC3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ccnc(N3CCCC3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-Amino-4-(4-chlorophenyl)-6-pyrrolidin-1-ylpyridine-3,5-dicarbonitrile chemical structure, C17H14ClN5, CAS 77034-29-8
2-Amino-4-(4-chlorophenyl)-6-pyrrolidin-1-ylpyridine-3,5-dicarbonitrile
CAS 77034-29-8C17H14ClN5
2-Amino-4-phenyl-6-(pyrrolidin-1-yl)pyridine-3,5-dicarbonitrile chemical structure, C17H15N5, CAS 77034-27-6
2-Amino-4-phenyl-6-(pyrrolidin-1-yl)pyridine-3,5-dicarbonitrile
CAS 77034-27-6C17H15N5
2-Amino-4-(4-methoxyphenyl)-6-(1-pyrrolidinyl)-3,5-pyridinedicarbonitrile chemical structure, C18H17N5O, CAS 77034-28-7
2-Amino-4-(4-methoxyphenyl)-6-(1-pyrrolidinyl)-3,5-pyridinedicarbonitrile
CAS 77034-28-7C18H17N5O
3-Pyridinecarbonitrile, 6-methyl-4-phenyl-2-(1-pyrrolidinyl)- chemical structure, C17H17N3, CAS 61006-41-5
3-Pyridinecarbonitrile, 6-methyl-4-phenyl-2-(1-pyrrolidinyl)-
CAS 61006-41-5C17H17N3
3-[2-(1-Pyrrolidinyl)-4-pyridinyl]benzonitrile chemical structure, C16H15N3, CAS 579476-73-6
3-[2-(1-Pyrrolidinyl)-4-pyridinyl]benzonitrile
CAS 579476-73-6C16H15N3
3-Oxo-3-[3-(2-pyrrolidin-1-yl-pyridin-4-yl)-phenyl]-propionic acid tert-butyl ester chemical structure, C22H26N2O3, CAS 579476-72-5
3-Oxo-3-[3-(2-pyrrolidin-1-yl-pyridin-4-yl)-phenyl]-propionic acid tert-butyl ester
CAS 579476-72-5C22H26N2O3