CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

21 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
21
With full pages
6
Scaffold SMILES

c1ccc(-c2nccc(N3CCCC3)n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nccc(N3CCCC3)n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

1-(4-Methylsulfanyl-2-phenyl-6-pyrrolidin-1-ylpyrimidin-5-yl)ethanone chemical structure, C17H19N3OS, CAS 312271-56-0
1-(4-Methylsulfanyl-2-phenyl-6-pyrrolidin-1-ylpyrimidin-5-yl)ethanone
CAS 312271-56-0C17H19N3OS
Isopropyl 2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl sulfide chemical structure, C17H21N3S, CAS 724740-37-8
Isopropyl 2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl sulfide
CAS 724740-37-8C17H21N3S
Ethyl 2-phenyl-4-(1-pyrrolidinyl)-5-pyrimidinecarboxylate chemical structure, C17H19N3O2, CAS 477854-67-4
Ethyl 2-phenyl-4-(1-pyrrolidinyl)-5-pyrimidinecarboxylate
CAS 477854-67-4C17H19N3O2
Methyl [2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl]methyl ether chemical structure, C16H19N3O, CAS 339278-93-2
Methyl [2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl]methyl ether
CAS 339278-93-2C16H19N3O
4-(Methanesulfonylmethyl)-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine chemical structure, C16H19N3O2S, CAS 339279-17-3
4-(Methanesulfonylmethyl)-2-phenyl-6-(pyrrolidin-1-yl)pyrimidine
CAS 339279-17-3C16H19N3O2S
Isopropyl [2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl]methyl sulfide chemical structure, C18H23N3S, CAS 338961-42-5
Isopropyl [2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl]methyl sulfide
CAS 338961-42-5C18H23N3S
Methyl 2-phenyl-4-(1-pyrrolidinyl)-5-pyrimidinyl sulfone chemical structure, C15H17N3O2S, CAS 478080-82-9
Methyl 2-phenyl-4-(1-pyrrolidinyl)-5-pyrimidinyl sulfone
CAS 478080-82-9C15H17N3O2S
4-Pyrimidineacetamide, N-hydroxy-6-(1-pyrrolidinyl)-2-(3,4,5-trimethoxyphenyl)- chemical structure, C19H24N4O5, CAS 42055-66-3
4-Pyrimidineacetamide, N-hydroxy-6-(1-pyrrolidinyl)-2-(3,4,5-trimethoxyphenyl)-
CAS 42055-66-3C19H24N4O5
4-Pyrimidineacetamide, N-hydroxy-6-(1-pyrrolidinyl)-2-(3-(trifluoromethyl)phenyl)- chemical structure, C17H17F3N4O2, CAS 42055-70-9
4-Pyrimidineacetamide, N-hydroxy-6-(1-pyrrolidinyl)-2-(3-(trifluoromethyl)phenyl)-
CAS 42055-70-9C17H17F3N4O2
4-Pyrimidineacetamide, 2-(3-chlorophenyl)-N-hydroxy-6-(1-pyrrolidinyl)- chemical structure, C16H17ClN4O2, CAS 42055-75-4
4-Pyrimidineacetamide, 2-(3-chlorophenyl)-N-hydroxy-6-(1-pyrrolidinyl)-
CAS 42055-75-4C16H17ClN4O2
4-Pyrimidineacetamide, 2-(3-fluorophenyl)-N-hydroxy-6-(1-pyrrolidinyl)- chemical structure, C16H17FN4O2, CAS 42055-81-2
4-Pyrimidineacetamide, 2-(3-fluorophenyl)-N-hydroxy-6-(1-pyrrolidinyl)-
CAS 42055-81-2C16H17FN4O2
Methyl [2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl]methyl sulfide chemical structure, C16H19N3S, CAS 338967-52-5
Methyl [2-phenyl-6-(1-pyrrolidinyl)-4-pyrimidinyl]methyl sulfide
CAS 338967-52-5C16H19N3S
5-Methoxy-2-phenyl-4-(1-pyrrolidinyl)pyrimidine chemical structure, C15H17N3O, CAS 477863-71-1
5-Methoxy-2-phenyl-4-(1-pyrrolidinyl)pyrimidine
CAS 477863-71-1C15H17N3O
2-(4-Methoxyphenyl)-4-(pyrrolidin-1-yl)pyrimidine-5-carboxylic acid chemical structure, C16H17N3O3, CAS 1081288-11-0
2-(4-Methoxyphenyl)-4-(pyrrolidin-1-yl)pyrimidine-5-carboxylic acid
CAS 1081288-11-0C16H17N3O3
[2-(3,4-Dimethoxy-phenyl)-6-pyrrolidin-1-yl-pyrimidin-4-yl]-methanol chemical structure, C17H21N3O3, CAS 1215358-10-3
[2-(3,4-Dimethoxy-phenyl)-6-pyrrolidin-1-yl-pyrimidin-4-yl]-methanol
CAS 1215358-10-3C17H21N3O3
2-Phenyl-4-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile chemical structure, C15H14N4, CAS 823796-04-9
2-Phenyl-4-(pyrrolidin-1-yl)pyrimidine-5-carbonitrile
CAS 823796-04-9C15H14N4
5-Bromo-2-phenyl-4-(pyrrolidin-1-yl)pyrimidine chemical structure, C14H14BrN3, CAS 823796-12-9
5-Bromo-2-phenyl-4-(pyrrolidin-1-yl)pyrimidine
CAS 823796-12-9C14H14BrN3
5-Chloro-2-phenyl-4-(pyrrolidin-1-yl)pyrimidine chemical structure, C14H14ClN3, CAS 823796-13-0
5-Chloro-2-phenyl-4-(pyrrolidin-1-yl)pyrimidine
CAS 823796-13-0C14H14ClN3
Methyl 2-(3,4-dimethoxyphenyl)-6-(1-pyrrolidinyl)-4-pyrimidinecarboxylate chemical structure, C18H21N3O4, CAS 1215358-08-9
Methyl 2-(3,4-dimethoxyphenyl)-6-(1-pyrrolidinyl)-4-pyrimidinecarboxylate
CAS 1215358-08-9C18H21N3O4
(S)-6-(3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxylic acid chemical structure, C16H17N3O3, CAS 1159501-69-5
(S)-6-(3-Methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carboxylic acid
CAS 1159501-69-5C16H17N3O3
6-[5-Butanoyl-6-(pyrrolidin-1-yl)pyrimidin-2(1H)-ylidene]cyclohexa-2,4-dien-1-one chemical structure, C18H21N3O2, CAS 823801-54-3
6-[5-Butanoyl-6-(pyrrolidin-1-yl)pyrimidin-2(1H)-ylidene]cyclohexa-2,4-dien-1-one
CAS 823801-54-3C18H21N3O2