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Murcko scaffold

Ring system with 3 rings and 17 atoms

32 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
32
With full pages
11
Scaffold SMILES

c1ccc(NC2CCNc3ccccc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(NC2CCNc3ccccc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone chemical structure, C18H20N2O, CAS 300801-70-1
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)ethanone
CAS 300801-70-1C18H20N2O
2,8-Dimethyl-N-(2-methylphenyl)-1,2,3,4-tetrahydroquinolin-4-amine chemical structure, C18H22N2, CAS 54306-48-8
2,8-Dimethyl-N-(2-methylphenyl)-1,2,3,4-tetrahydroquinolin-4-amine
CAS 54306-48-8C18H22N2
1-{2,8-Dimethyl-4-[(2-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}butan-1-one chemical structure, C22H28N2O, CAS 348131-29-3
1-{2,8-Dimethyl-4-[(2-methylphenyl)amino]-3,4-dihydroquinolin-1(2H)-yl}butan-1-one
CAS 348131-29-3C22H28N2O
N-[(2R,4S)-2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylacetamide chemical structure, C18H20N2O, CAS 681827-49-6
N-[(2R,4S)-2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylacetamide
CAS 681827-49-6C18H20N2O
4-Quinolinamine, 1-acetyl-1,2,3,4-tetrahydro-2,6-dimethyl-N-(4-methylphenyl)-, (2R,4S)-rel- chemical structure, C20H24N2O, CAS 26510-97-4
4-Quinolinamine, 1-acetyl-1,2,3,4-tetrahydro-2,6-dimethyl-N-(4-methylphenyl)-, (2R,4S)-rel-
CAS 26510-97-4C20H24N2O
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)pentan-1-one chemical structure, C21H26N2O, CAS 202065-36-9
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)pentan-1-one
CAS 202065-36-9C21H26N2O
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)hexan-1-one chemical structure, C22H28N2O, CAS 5228-47-7
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)hexan-1-one
CAS 5228-47-7C22H28N2O
1-[2-Methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]heptan-1-one chemical structure, C23H30N2O, CAS 202065-20-1
1-[2-Methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]heptan-1-one
CAS 202065-20-1C23H30N2O
N-[2-Methyl-1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-4-yl]-N-phenylacetamide chemical structure, C22H26N2O2, CAS 295363-83-6
N-[2-Methyl-1-(2-methylpropanoyl)-3,4-dihydro-2H-quinolin-4-yl]-N-phenylacetamide
CAS 295363-83-6C22H26N2O2
N-(1-Acetyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl)-N-phenylheptanamide chemical structure, C25H32N2O2, CAS 413616-20-3
N-(1-Acetyl-2-methyl-3,4-dihydro-2H-quinolin-4-yl)-N-phenylheptanamide
CAS 413616-20-3C25H32N2O2
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide chemical structure, C18H20N2O, CAS 54306-50-2
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylacetamide
CAS 54306-50-2C18H20N2O
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylbutanamide chemical structure, C20H24N2O, CAS 301355-28-2
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylbutanamide
CAS 301355-28-2C20H24N2O
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine chemical structure, C16H18N2, CAS 1026-05-7
2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine
CAS 1026-05-7C16H18N2
2,2,2-Trifluoro-N-(2-methyl-1-(trifluoroacetyl)-1,2,3,4-tetrahydro-4-quinolinyl)-N-phenylacetamide chemical structure, C20H16F6N2O2, CAS 306737-62-2
2,2,2-Trifluoro-N-(2-methyl-1-(trifluoroacetyl)-1,2,3,4-tetrahydro-4-quinolinyl)-N-phenylacetamide
CAS 306737-62-2C20H16F6N2O2
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylpropanamide chemical structure, C19H22N2O, CAS 304871-97-4
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylpropanamide
CAS 304871-97-4C19H22N2O
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylnonanamide chemical structure, C25H34N2O, CAS 331416-98-9
N-(2-Methyl-1,2,3,4-tetrahydroquinolin-4-yl)-N-phenylnonanamide
CAS 331416-98-9C25H34N2O
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-2,2-dimethylpropan-1-one chemical structure, C21H26N2O, CAS 332044-09-4
1-(4-Anilino-2-methyl-3,4-dihydro-2H-quinolin-1-yl)-2,2-dimethylpropan-1-one
CAS 332044-09-4C21H26N2O
2-Methyl-N-[2-methyl-1-(2-methylpropanoyl)-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylpropanamide chemical structure, C24H30N2O2, CAS 332074-50-7
2-Methyl-N-[2-methyl-1-(2-methylpropanoyl)-1,2,3,4-tetrahydroquinolin-4-yl]-N-phenylpropanamide
CAS 332074-50-7C24H30N2O2
Ethyl [2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl](oxo)acetate chemical structure, C20H22N2O3, CAS 314039-80-0
Ethyl [2-methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl](oxo)acetate
CAS 314039-80-0C20H22N2O3
Ethyl 2-[4-(N-(2-ethoxy-2-oxoacetyl)anilino)-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-2-oxoacetate chemical structure, C24H26N2O6, CAS 371219-07-7
Ethyl 2-[4-(N-(2-ethoxy-2-oxoacetyl)anilino)-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-2-oxoacetate
CAS 371219-07-7C24H26N2O6
4-[(2-Carboxyphenyl)amino]-3,3-dimethyl-2-(propan-2-yl)-1,2,3,4-tetrahydroquinoline-8-carboxylic acid chemical structure, C22H26N2O4, CAS 332861-95-7
4-[(2-Carboxyphenyl)amino]-3,3-dimethyl-2-(propan-2-yl)-1,2,3,4-tetrahydroquinoline-8-carboxylic acid
CAS 332861-95-7C22H26N2O4
2-Methyl-1-(2-methyl-4-phenylamino-3,4-dihydro-2H-quinolin-1-yl)-propan-1-one chemical structure, C20H24N2O, CAS 300852-13-5
2-Methyl-1-(2-methyl-4-phenylamino-3,4-dihydro-2H-quinolin-1-yl)-propan-1-one
CAS 300852-13-5C20H24N2O
Ethyl [(1-isobutyryl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)(phenyl)amino](oxo)acetate chemical structure, C24H28N2O4, CAS 511513-86-3
Ethyl [(1-isobutyryl-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)(phenyl)amino](oxo)acetate
CAS 511513-86-3C24H28N2O4
1-[2-Methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]butan-1-one chemical structure, C20H24N2O, CAS 201480-34-4
1-[2-Methyl-4-(phenylamino)-3,4-dihydroquinolin-1(2H)-yl]butan-1-one
CAS 201480-34-4C20H24N2O