Murcko scaffold
Ring system with 2 rings and 19 atoms
69 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 19
- Chemicals
- 69
- With full pages
- 7
Scaffold SMILES
C=C(N=Nc1ccccc1)C(=O)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 69 chemicals
Acid Yellow 99
C16H15CrN4NaO9S
![N-(4-Chlorophenyl)-2-[2-(2,3-dimethylphenyl)hydrazin-1-ylidene]-3-oxobutanamide chemical structure, C18H18ClN3O2](/s/DKIQJGXQXUSKEV-UHFFFAOYSA-N.svg)
N-(4-Chlorophenyl)-2-[2-(2,3-dimethylphenyl)hydrazin-1-ylidene]-3-oxobutanamide
C18H18ClN3O2
![(Z)-N-(4-Chlorophenyl)-2-[(2,3-dimethylphenyl)diazenyl]-3-hydroxybut-2-enamide chemical structure, C18H18ClN3O2, CAS 756842-11-2](/s/DKIQJGXQXUSKEV-NHHDTLDSSA-N.svg)
(Z)-N-(4-Chlorophenyl)-2-[(2,3-dimethylphenyl)diazenyl]-3-hydroxybut-2-enamide
CAS 756842-11-2C18H18ClN3O2
![(2E)-4,4,4-Trifluoro-3-oxo-N-[4-(trifluoromethyl)phenyl]-2-{2-[4-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide chemical structure, C18H10F9N3O2, CAS 866131-03-5](/s/SCQSORQZTLOSOR-WDDOPMHVSA-N.svg)
(2E)-4,4,4-Trifluoro-3-oxo-N-[4-(trifluoromethyl)phenyl]-2-{2-[4-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide
CAS 866131-03-5C18H10F9N3O2
![3-[(1-Anilino-3-hydroxy-1-oxobut-2-en-2-yl)diazenyl]-2-hydroxy-5-nitrobenzenesulfonate chemical structure, C16H13N4O8S-](/s/HKQZMDSBRPNNKY-UHFFFAOYSA-M.svg)
3-[(1-Anilino-3-hydroxy-1-oxobut-2-en-2-yl)diazenyl]-2-hydroxy-5-nitrobenzenesulfonate
C16H13N4O8S-
Acid Yellow 99 (C.I. 13900)
C16H13CrN4NaO8S
![4,4,4-Trifluoro-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-[[4-(trifluoromethyl)phenyl]diazenyl]but-2-enamide chemical structure, C18H10F9N3O2](/s/SCQSORQZTLOSOR-UHFFFAOYSA-N.svg)
4,4,4-Trifluoro-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-[[4-(trifluoromethyl)phenyl]diazenyl]but-2-enamide
C18H10F9N3O2
![(2Z)-4,4,4-Trifluoro-3-oxo-N-[3-(trifluoromethyl)phenyl]-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide chemical structure, C18H10F9N3O2](/s/RRZFSLKDSWRZIO-DKBDZDHVSA-N.svg)
(2Z)-4,4,4-Trifluoro-3-oxo-N-[3-(trifluoromethyl)phenyl]-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide
C18H10F9N3O2
![4,4,4-Trifluoro-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-[[3-(trifluoromethyl)phenyl]diazenyl]but-2-enamide chemical structure, C18H10F9N3O2](/s/RRZFSLKDSWRZIO-UHFFFAOYSA-N.svg)
4,4,4-Trifluoro-3-hydroxy-N-[3-(trifluoromethyl)phenyl]-2-[[3-(trifluoromethyl)phenyl]diazenyl]but-2-enamide
C18H10F9N3O2
Hansayellow
CAS 1089943-13-4C17H16N4O4
![N-(2,3-Dichlorophenyl)-4,4,4-trifluoro-3-oxo-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide chemical structure, C17H9Cl2F6N3O2, CAS 478067-07-1](/s/ZQIRQBUQDRCMEG-ULUWNGJXSA-N.svg)
N-(2,3-Dichlorophenyl)-4,4,4-trifluoro-3-oxo-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide
CAS 478067-07-1C17H9Cl2F6N3O2
Chromium, (2-(hydroxy-kappaO)-5-nitro-3-(2-(2-(oxo-kappaO)-1-((phenylamino)carbonyl)propyl)diazenyl-kappaN1)benzenesulfonato(3-))-
CAS 10343-55-2C16H11CrN4O8S
![Sodium hydroxy[2-hydroxy-5-nitro-3-[[2-oxo-1-(phenylcarbamoyl)propyl]azo]benzenesulphonato(3-)]chromate(1-) chemical structure, C16H12CrN4NaO9S, CAS 10343-58-5](/s/XEAHZUQHDDJSJW-QRCYWBJZSA-J.svg)
Sodium hydroxy[2-hydroxy-5-nitro-3-[[2-oxo-1-(phenylcarbamoyl)propyl]azo]benzenesulphonato(3-)]chromate(1-)
CAS 10343-58-5C16H12CrN4NaO9S
![(2Z)-2-[(4-Methyl-2-nitrophenyl)hydrazono]-3-oxo-N-phenylbutanamide chemical structure, C17H16N4O4, CAS 89705-72-6](/s/QGNDAXYFYSPDKJ-PQUVRPEGSA-N.svg)
(2Z)-2-[(4-Methyl-2-nitrophenyl)hydrazono]-3-oxo-N-phenylbutanamide
CAS 89705-72-6C17H16N4O4
![4,4,4-Trifluoro-3-oxo-N-[3-(trifluoromethyl)phenyl]-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide chemical structure, C18H10F9N3O2, CAS 478067-06-0](/s/RRZFSLKDSWRZIO-WDDOPMHVSA-N.svg)
4,4,4-Trifluoro-3-oxo-N-[3-(trifluoromethyl)phenyl]-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide
CAS 478067-06-0C18H10F9N3O2
![(2E)-4,4,4-Trifluoro-N-(4-methoxyphenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide chemical structure, C18H13F6N3O3, CAS 866130-99-6](/s/IXLJOMZFICIDPF-OHNRMDLPSA-N.svg)
(2E)-4,4,4-Trifluoro-N-(4-methoxyphenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide
CAS 866130-99-6C18H13F6N3O3
![(2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide chemical structure, C17H10F7N3O2, CAS 866131-00-2](/s/WPPTVEHEWDPWKP-YPBBWVHZSA-N.svg)
(2E)-4,4,4-Trifluoro-N-(4-fluorophenyl)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide
CAS 866131-00-2C17H10F7N3O2
![(2E)-4,4,4-Trifluoro-N-methyl-3-oxo-N-phenyl-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide chemical structure, C18H13F6N3O2, CAS 400087-23-2](/s/KRJQNQKLXNNIMA-ZRBLHNNDSA-N.svg)
(2E)-4,4,4-Trifluoro-N-methyl-3-oxo-N-phenyl-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanamide
CAS 400087-23-2C18H13F6N3O2
![2-[2-(2-Hydroxyphenyl)hydrazinylidene]-3-oxo-N-phenylbutanamide chemical structure, C16H15N3O3, CAS 62269-12-9](/s/BQHPDIXTUFTCKP-MAMKXJJPSA-N.svg)
2-[2-(2-Hydroxyphenyl)hydrazinylidene]-3-oxo-N-phenylbutanamide
CAS 62269-12-9C16H15N3O3
![N-(3,5-Dichlorophenyl)-4,4,4-trifluoro-3-oxo-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide chemical structure, C17H9Cl2F6N3O2, CAS 866131-02-4](/s/RTIDEZWOIKNYFF-ULUWNGJXSA-N.svg)
N-(3,5-Dichlorophenyl)-4,4,4-trifluoro-3-oxo-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide
CAS 866131-02-4C17H9Cl2F6N3O2
![N-(2,4-Difluorophenyl)-4,4,4-trifluoro-3-oxo-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide chemical structure, C17H9F8N3O2, CAS 866131-01-3](/s/RNWIXUPNUUYJOL-ULUWNGJXSA-N.svg)
N-(2,4-Difluorophenyl)-4,4,4-trifluoro-3-oxo-2-{(Z)-2-[3-(trifluoromethyl)phenyl]hydrazono}butanamide
CAS 866131-01-3C17H9F8N3O2
Cobalt, bis(2-(2-(2-(hydroxy-kappaO)-5-((methylamino)sulfonyl)phenyl)diazenyl-kappaN1)-3-(oxo-kappaO)-N-phenylbutanamidato(2-))-
CAS 69178-42-3C34H32CoN8O10S2-4
![2-[(4-Methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide chemical structure, C17H16N4O4, CAS 26128-86-9](/s/QGNDAXYFYSPDKJ-UHFFFAOYSA-N.svg)
2-[(4-Methyl-2-nitro-phenyl)hydrazono]-3-oxo-N-phenyl-butanamide
CAS 26128-86-9C17H16N4O4
Chromate(3-), bis(2-(hydroxy-kappaO)-5-nitro-3-((2-(oxo-kappaO)-1-((phenylamino)carbonyl)propyl)azo-kappaN1)benzenesulfonato(3-))-, trihydrogen
CAS 72796-99-7C32H25CrN8O16S2
- C.I. Acid Yellow 99C16H13CrN4NaO8S
- Chromate(1-), [4-(aminosulfonyl)-2-[[1-[[(2-methylphenyl)amino]carbonyl]-2-(oxo-kappaO)propyl]azo-kappaN1]benzoato(2-)-kappaO][N-[8-[[4-chloro-2-(hydroxy-kappaO)-5-methoxyphenyl]azo-kappaN1]-7-(hydroxy-kappaO)-1-naphthalenyl]methanesulfonamidato(2-)]-, sodiumC36H30ClCrN7NaO11S2
- Cobaltate(1-), bis(2-(2-(2-(hydroxy-kappaO)-4-nitrophenyl)diazenyl-kappaN1)-3-(oxo-kappaO)-N-phenylbutanamidato(2-))-, sodium (1:1)81361-02-6C32H24CoN8NaO10
- Cobaltate(2-), bis[2-[2-[5-(aminosulfonyl)-2-(hydroxy-kappaO)phenyl]diazenyl-kappaN1]-3-(oxo-kappaO)-N-phenylbutanamidato(2-)]-, sodium (1:2)75522-91-7C32H28CoN8Na2O10S2
- RefChem:57799693776-36-4C33H25ClCoN8NaO8S
- Cobaltate(1-), bis[2-[2-[4-(aminosulfonyl)-2-(hydroxy-kappaO)phenyl]diazenyl-kappaN1]-3-(oxo-kappaO)-N-phenylbutanamidato(2-)]-, sodium (1:1)66104-83-4C32H28CoN8NaO10S2
- Lithium bis(2-((2-hydroxy-5-nitrophenyl)azo)-3-oxo-N-phenylbutyramidato(2-))cobaltate(1-)83733-13-5C32H28CoLiN8O10+
- Disodium (5-((1-(anilinocarbonyl)-2-oxopropyl)azo)-4-hydroxy-3-nitrobenzenesulphonato(3-))(2-((2-hydroxy-5-nitrophenyl)azo)-3-oxo-N-phenylbutyramidato(2-))cobaltate(2-)76762-27-1C32H28CoN8Na2O13S+2
- Sodium bis(N-(2-chlorophenyl)-2-((2-hydroxy-5-mesylphenyl)azo)-3-oxobutyramidato(2-))cobaltate(1-)94246-68-1C34H32Cl2CoN6NaO10S2+
- Trisodium bis(4-hydroxy-3-nitro-5-((2-oxo-1-((phenylamino)carbonyl)propyl)azo)benzenesulphonato(3-))cobaltate(3-)83733-22-6C32H28CoN8Na3O16S2+3
- RefChem:88662694232-97-0C32H29CoN9NaO12S+
- Cobaltate(1-), bis[2-[2-[2-(hydroxy-kappaO)-5-nitrophenyl]diazenyl-kappaN1]-3-(oxo-kappaO)-N-phenylbutanamidato(2-)]-, sodium (1:1)71566-26-2C32H24CoN8NaO10
- Chromate(1-), (4-(aminosulfonyl)-2-((1-(((2-methylphenyl)amino)carbonyl)-2-(oxo-kappaO)propyl)azo-kappaN1)benzoato(2-)-kappaO)(N-(8-((4-chloro-2-(hydroxy-kappaO)-5-methoxyphenyl)azo-kappaN1)-7-(hydroxy-kappaO)-1-naphthalenyl)methanesulfonamidato(2-))-, sodium86262-20-6C36H30ClCrN7NaO11S2
- 4,4,4-Trifluoro-3-oxo-N-[4-(trifluoromethyl)phenyl]-2-{(Z)-2-[4-(trifluoromethyl)phenyl]hydrazono}butanamideC18H10F9N3O2
- Sodium bis(2-((2-hydroxy-5-nitrophenyl)azo)-3-oxo-N-phenylbutyramidate(2-))chromate(1-)94232-95-8C32H28CrN8NaO10+
- Sodium bis(2-((2-hydroxy-5-((isopropylamino)sulphonyl)phenyl)azo)-3-oxo-N-phenylbutyramidato(2-))cobaltate(1-)94246-69-2C38H44CoN8NaO10S2+
- Lithium bis(2-((5-(aminosulphonyl)-2-hydroxyphenyl)azo)-3-oxo-N-phenylbutyramidato(2-))cobaltate(1-)83249-68-7C32H32CoLiN8O10S2+
- Chromium(3+) 3-[(1-anilino-1,3-dioxobutan-2-id-2-yl)diazenyl]-5-nitro-2-oxidobenzene-1-sulfonateC16H11CrN4O8S
- Cobaltate(1-), bis(2-(2-(5-(aminosulfonyl)-2-(hydroxy-kappaO)phenyl)diazenyl-kappaN1)-3-(oxo-kappaO)-N-phenylbutanamidato(2-))-, hydrogen (1:1)72928-91-7C32H29CoN8O10S2
- Chromate(5-), bis[5-[[1-(acetyl-kappaO)-2-oxo-2-(phenylamino)ethyl]azo-kappaN1]-4-(hydroxy-kappaO)-1,3-benzenedisulfonato(4-)]-, potassium tetrasodiumC32H26CrKN6Na4O18S4+
- 2-[2-(4-Methylphenyl)hydrazinylidene]-3-oxo-N-phenylbutanamide62269-10-7C17H17N3O2
- N-(4-Methoxyphenyl)-3-oxo-2-(2-phenylhydrazinylidene)butanamide62269-15-2C17H17N3O3
- 2-[2-(3-Methylphenyl)hydrazinylidene]-3-oxo-N-phenylbutanamide62269-11-8C17H17N3O2
- 2-[2-(2-Methoxyphenyl)hydrazinylidene]-3-oxo-N-phenylbutanamide62269-09-4C17H17N3O3
Related scaffolds
Same ring framework with different atoms or bond orders
S=C(NN=Cc1ccccc1)Nc1ccccc1105 chemicals
S=C(NCCc1ccccc1)Nc1ccccc160 chemicals
c1ccc(CCNCCc2ccccc2)cc158 chemicals
O=C(COc1ccccc1)NCc1ccccc146 chemicals
O=C(NCCOc1ccccc1)c1ccccc146 chemicals
O=C(C=Cc1ccccc1)NCc1ccccc143 chemicals
c1ccc(OCCCOc2ccccc2)cc141 chemicals
O=C(CC(=O)Nc1ccccc1)Nc1ccccc137 chemicals
O=C(CNS(=O)(=O)c1ccccc1)Nc1ccccc136 chemicals
O=C(CSCc1ccccc1)Nc1ccccc133 chemicals
O=C(Cc1ccccc1)NCCc1ccccc132 chemicals
O=C(CNCc1ccccc1)Nc1ccccc131 chemicals