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Murcko scaffold

5H,6H,7H-Pyrrolo(3,4-b)pyridin-5-one scaffold

65 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
65
With full pages
7
Scaffold SMILES

O=C1NCc2ncccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5H,6H,7H-Pyrrolo(3,4-b)pyridin-5-one page
Murcko scaffold O=C1NCc2ncccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

5H,6H,7H-Pyrrolo(3,4-b)pyridin-5-one chemical structure, C7H6N2O, CAS 40107-93-5
5H,6H,7H-Pyrrolo(3,4-b)pyridin-5-one
CAS 40107-93-5C7H6N2O
7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C7H6N2O2, CAS 115012-09-4
7-Hydroxy-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 115012-09-4C7H6N2O2
6,7-Dihydro-7-methoxy-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C8H8N2O2, CAS 115012-13-0
6,7-Dihydro-7-methoxy-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 115012-13-0C8H8N2O2
7-Amino-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C7H7N3O, CAS 115012-14-1
7-Amino-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 115012-14-1C7H7N3O
6-[(2R)-1-Hydroxy-3-methylbutan-2-yl]-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C12H16N2O2, CAS 1268952-43-7
6-[(2R)-1-Hydroxy-3-methylbutan-2-yl]-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one
CAS 1268952-43-7C12H16N2O2
6-(3-Aminopropyl)-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C10H13N3O, CAS 1206970-28-6
6-(3-Aminopropyl)-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one
CAS 1206970-28-6C10H13N3O
6-(2-Aminoethyl)-6,7-dihydropyrrolo[3,4-b]pyridin-5-one chemical structure, C9H11N3O, CAS 1206970-12-8
6-(2-Aminoethyl)-6,7-dihydropyrrolo[3,4-b]pyridin-5-one
CAS 1206970-12-8C9H11N3O
2-(5-Oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)acetic acid chemical structure, C9H8N2O3, CAS 1206970-09-3
2-(5-Oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)acetic acid
CAS 1206970-09-3C9H8N2O3
2-Chloro-6-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C8H7ClN2O, CAS 1201924-14-2
2-Chloro-6-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 1201924-14-2C8H7ClN2O
2-Chloro-6-(2-hydroxyethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C9H9ClN2O2, CAS 1201924-06-2
2-Chloro-6-(2-hydroxyethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 1201924-06-2C9H9ClN2O2
6-Methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C8H8N2O, CAS 40107-94-6
6-Methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 40107-94-6C8H8N2O
2-Chloro-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C7H5ClN2O, CAS 1256811-82-1
2-Chloro-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one
CAS 1256811-82-1C7H5ClN2O
3-Methyl-6,7-dihydropyrrolo[3,4-b]pyridin-5-one chemical structure, C8H8N2O, CAS 1256820-96-8
3-Methyl-6,7-dihydropyrrolo[3,4-b]pyridin-5-one
CAS 1256820-96-8C8H8N2O
3-Hydroxy-6-methyl-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one chemical structure, C8H8N2O2, CAS 1391732-76-5
3-Hydroxy-6-methyl-6,7-dihydro-pyrrolo[3,4-b]pyridin-5-one
CAS 1391732-76-5C8H8N2O2
3-Bromo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C7H5BrN2O, CAS 1211589-13-7
3-Bromo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 1211589-13-7C7H5BrN2O
3-Fluoro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C7H5FN2O, CAS 1256790-95-0
3-Fluoro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 1256790-95-0C7H5FN2O
3-Hydroxy-6,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one chemical structure, C9H10N2O2, CAS 1391732-96-9
3-Hydroxy-6,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one
CAS 1391732-96-9C9H10N2O2
2-Chloro-7,7-dimethyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C9H9ClN2O, CAS 1440519-75-4
2-Chloro-7,7-dimethyl-5H,6H,7H-pyrrolo[3,4-b]pyridin-5-one
CAS 1440519-75-4C9H9ClN2O
2-Methoxy-7,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one chemical structure, C10H12N2O2, CAS 1440519-80-1
2-Methoxy-7,7-dimethyl-6,7-dihydro-5H-pyrrolo[3,4-B]pyridin-5-one
CAS 1440519-80-1C10H12N2O2
6-(2-Hydroxyethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C9H10N2O2, CAS 136842-80-3
6-(2-Hydroxyethyl)-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 136842-80-3C9H10N2O2
2-Chloro-4-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C8H7ClN2O, CAS 1315544-70-7
2-Chloro-4-methyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 1315544-70-7C8H7ClN2O
3-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one chemical structure, C7H5ClN2O, CAS 1256806-34-4
3-Chloro-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-5-one
CAS 1256806-34-4C7H5ClN2O
5H-Pyrrolo[3,4-b]pyridin-5-one,6-(3-dimethylaminopropyl)-6,7-dihydro- chemical structure, C12H17N3O, CAS 109097-66-7
5H-Pyrrolo[3,4-b]pyridin-5-one,6-(3-dimethylaminopropyl)-6,7-dihydro-
CAS 109097-66-7C12H17N3O
5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-2-(trifluoromethyl)- chemical structure, C8H5F3N2O, CAS 1256786-54-5
5H-Pyrrolo[3,4-b]pyridin-5-one,6,7-dihydro-2-(trifluoromethyl)-
CAS 1256786-54-5C8H5F3N2O