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Murcko scaffold

Ring system with 2 rings and 15 atoms

9 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
9
With full pages
4
Scaffold SMILES

O=C(CSc1ccsn1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1ccsn1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

5-Methyl-3-[(2-oxo-2-phenylethyl)sulfanyl]-4-isothiazolecarbonitrile chemical structure, C13H10N2OS2, CAS 338418-03-4
5-Methyl-3-[(2-oxo-2-phenylethyl)sulfanyl]-4-isothiazolecarbonitrile
CAS 338418-03-4C13H10N2OS2
5-Methyl-3-{[2-(4-methylphenyl)-2-oxoethyl]sulfanyl}-4-isothiazolecarbonitrile chemical structure, C14H12N2OS2, CAS 343372-91-8
5-Methyl-3-{[2-(4-methylphenyl)-2-oxoethyl]sulfanyl}-4-isothiazolecarbonitrile
CAS 343372-91-8C14H12N2OS2
3-{[2-(2-Chlorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile chemical structure, C13H9ClN2OS2, CAS 343372-94-1
3-{[2-(2-Chlorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile
CAS 343372-94-1C13H9ClN2OS2
3-{[2-(2,4-Dichlorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile chemical structure, C13H8Cl2N2OS2, CAS 343372-95-2
3-{[2-(2,4-Dichlorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile
CAS 343372-95-2C13H8Cl2N2OS2
3-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile chemical structure, C13H9ClN2OS2, CAS 343375-34-8
3-{[2-(4-Chlorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile
CAS 343375-34-8C13H9ClN2OS2
3-{[2-(4-Fluorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile chemical structure, C13H9FN2OS2, CAS 339017-14-0
3-{[2-(4-Fluorophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile
CAS 339017-14-0C13H9FN2OS2
3-{[2-(4-Bromophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile chemical structure, C13H9BrN2OS2, CAS 339017-15-1
3-{[2-(4-Bromophenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile
CAS 339017-15-1C13H9BrN2OS2
3-{[2-(4-Methoxyphenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile chemical structure, C14H12N2O2S2, CAS 339017-16-2
3-{[2-(4-Methoxyphenyl)-2-oxoethyl]sulfanyl}-5-methyl-4-isothiazolecarbonitrile
CAS 339017-16-2C14H12N2O2S2
5-Methyl-3-{[2-(4-nitrophenyl)-2-oxoethyl]sulfanyl}-4-isothiazolecarbonitrile chemical structure, C13H9N3O3S2, CAS 343372-92-9
5-Methyl-3-{[2-(4-nitrophenyl)-2-oxoethyl]sulfanyl}-4-isothiazolecarbonitrile
CAS 343372-92-9C13H9N3O3S2