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Murcko scaffold

Ring system with 3 rings and 17 atoms

55 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
55
With full pages
4
Scaffold SMILES

O=C1OC(Nc2ccccc2)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1OC(Nc2ccccc2)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 55 chemicals

3-Anilino-3-methyl-2-benzofuran-1(3H)-one chemical structure, C15H13NO2, CAS 7505-84-2
3-Anilino-3-methyl-2-benzofuran-1(3H)-one
CAS 7505-84-2C15H13NO2
3-(3-Fluoroanilino)-3H-2-benzofuran-1-one chemical structure, C14H10FNO2, CAS 312266-04-9
3-(3-Fluoroanilino)-3H-2-benzofuran-1-one
CAS 312266-04-9C14H10FNO2
3-(4-Fluoro-phenylamino)-3H-isobenzofuran-1-one chemical structure, C14H10FNO2, CAS 309926-32-7
3-(4-Fluoro-phenylamino)-3H-isobenzofuran-1-one
CAS 309926-32-7C14H10FNO2
1H-Isobenzofuran-1(3H)-one, 3-(4-hydroxyphenylamino)-6,7-dimethoxy- chemical structure, C16H15NO5, CAS 307339-70-4
1H-Isobenzofuran-1(3H)-one, 3-(4-hydroxyphenylamino)-6,7-dimethoxy-
CAS 307339-70-4C16H15NO5
3-(3-Fluoro-phenylamino)-6,7-dimethoxy-3H-isobenzofuran-1-one chemical structure, C16H14FNO4, CAS 339287-21-7
3-(3-Fluoro-phenylamino)-6,7-dimethoxy-3H-isobenzofuran-1-one
CAS 339287-21-7C16H14FNO4
Methyl 2-[(3-oxo-1,3-dihydro-2-benzofuran-1-yl)amino]benzoate chemical structure, C16H13NO4, CAS 42974-48-1
Methyl 2-[(3-oxo-1,3-dihydro-2-benzofuran-1-yl)amino]benzoate
CAS 42974-48-1C16H13NO4
3-((2,4-Difluorophenyl)amino)isobenzofuran-1(3H)-one chemical structure, C14H9F2NO2, CAS 663884-80-8
3-((2,4-Difluorophenyl)amino)isobenzofuran-1(3H)-one
CAS 663884-80-8C14H9F2NO2
3-[(4-Acetylphenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C18H17NO5, CAS 298193-81-4
3-[(4-Acetylphenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 298193-81-4C18H17NO5
6,7-Dimethoxy-3-(4-methylanilino)-3H-2-benzofuran-1-one chemical structure, C17H17NO4, CAS 325750-25-2
6,7-Dimethoxy-3-(4-methylanilino)-3H-2-benzofuran-1-one
CAS 325750-25-2C17H17NO4
6,7-Dimethoxy-3-[(4-methoxyphenyl)amino]-2-benzofuran-1(3H)-one chemical structure, C17H17NO5, CAS 307339-72-6
6,7-Dimethoxy-3-[(4-methoxyphenyl)amino]-2-benzofuran-1(3H)-one
CAS 307339-72-6C17H17NO5
3-(2,5-Dimethoxyanilino)-6,7-dimethoxy-3H-2-benzofuran-1-one chemical structure, C18H19NO6, CAS 330202-34-1
3-(2,5-Dimethoxyanilino)-6,7-dimethoxy-3H-2-benzofuran-1-one
CAS 330202-34-1C18H19NO6
3-(2-Hydroxy-5-methylanilino)-6,7-dimethoxy-3H-2-benzofuran-1-one chemical structure, C17H17NO5, CAS 337932-80-6
3-(2-Hydroxy-5-methylanilino)-6,7-dimethoxy-3H-2-benzofuran-1-one
CAS 337932-80-6C17H17NO5
5-((4,5-Dimethoxy-3-oxo-1,3-dihydroisobenzofuran-1-yl)amino)isophthalic acid chemical structure, C18H15NO8, CAS 325750-31-0
5-((4,5-Dimethoxy-3-oxo-1,3-dihydroisobenzofuran-1-yl)amino)isophthalic acid
CAS 325750-31-0C18H15NO8
4-((4,5-Dimethoxy-3-oxo-1,3-dihydroisobenzofuran-1-yl)amino)benzoic acid chemical structure, C17H15NO6, CAS 307339-68-0
4-((4,5-Dimethoxy-3-oxo-1,3-dihydroisobenzofuran-1-yl)amino)benzoic acid
CAS 307339-68-0C17H15NO6
6,7-Dimethoxy-3-{[3-(trifluoromethyl)phenyl]amino}-2-benzofuran-1(3H)-one chemical structure, C17H14F3NO4, CAS 339205-75-3
6,7-Dimethoxy-3-{[3-(trifluoromethyl)phenyl]amino}-2-benzofuran-1(3H)-one
CAS 339205-75-3C17H14F3NO4
3-{[2-Chloro-5-(trifluoromethyl)phenyl]amino}-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C17H13ClF3NO4, CAS 330202-35-2
3-{[2-Chloro-5-(trifluoromethyl)phenyl]amino}-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 330202-35-2C17H13ClF3NO4
Methyl 2-[(4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl)amino]benzoate chemical structure, C18H17NO6, CAS 313240-04-9
Methyl 2-[(4,5-dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl)amino]benzoate
CAS 313240-04-9C18H17NO6
3-[(4-Iodophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C16H14INO4, CAS 330202-33-0
3-[(4-Iodophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 330202-33-0C16H14INO4
6,7-Dimethoxy-3-(3-nitroanilino)-3H-2-benzofuran-1-one chemical structure, C16H14N2O6, CAS 311316-98-0
6,7-Dimethoxy-3-(3-nitroanilino)-3H-2-benzofuran-1-one
CAS 311316-98-0C16H14N2O6
3-[(3-Chloro-4-fluorophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C16H13ClFNO4, CAS 327072-34-4
3-[(3-Chloro-4-fluorophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 327072-34-4C16H13ClFNO4
4-[(4,5-Dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl)amino]benzenesulfonamide chemical structure, C16H16N2O6S, CAS 337932-83-9
4-[(4,5-Dimethoxy-3-oxo-1,3-dihydro-2-benzofuran-1-yl)amino]benzenesulfonamide
CAS 337932-83-9C16H16N2O6S
3-[(3-Chlorophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C16H14ClNO4, CAS 313704-95-9
3-[(3-Chlorophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 313704-95-9C16H14ClNO4
3-(4-Bromoanilino)-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C16H14BrNO4, CAS 5987-32-6
3-(4-Bromoanilino)-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 5987-32-6C16H14BrNO4
3-[(3-Bromophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one chemical structure, C16H14BrNO4, CAS 371958-31-5
3-[(3-Bromophenyl)amino]-6,7-dimethoxy-2-benzofuran-1(3H)-one
CAS 371958-31-5C16H14BrNO4