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Murcko scaffold

Ring system with 4 rings and 20 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
12
With full pages
4
Scaffold SMILES

O=c1oc2ccccc2cc1-c1cn2ccccc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1oc2ccccc2cc1-c1cn2ccccc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

3-(6-Chloroimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one chemical structure, C16H9ClN2O2, CAS 313536-23-1
3-(6-Chloroimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one
CAS 313536-23-1C16H9ClN2O2
3-(8-Methyl-2-imidazo[1,2-a]pyridinyl)-1-benzopyran-2-one chemical structure, C17H12N2O2, CAS 326913-55-7
3-(8-Methyl-2-imidazo[1,2-a]pyridinyl)-1-benzopyran-2-one
CAS 326913-55-7C17H12N2O2
8-Methoxy-3-(8-methylimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one chemical structure, C18H14N2O3, CAS 337485-49-1
8-Methoxy-3-(8-methylimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one
CAS 337485-49-1C18H14N2O3
6-Methoxy-3-{7-methylimidazo[1,2-a]pyridin-2-yl}-2H-chromen-2-one chemical structure, C18H14N2O3, CAS 330832-38-7
6-Methoxy-3-{7-methylimidazo[1,2-a]pyridin-2-yl}-2H-chromen-2-one
CAS 330832-38-7C18H14N2O3
3-(7-Methylimidazo[1,2-a]pyridin-2-yl)chromen-2-one chemical structure, C17H12N2O2, CAS 324759-60-6
3-(7-Methylimidazo[1,2-a]pyridin-2-yl)chromen-2-one
CAS 324759-60-6C17H12N2O2
6-Bromo-3-{7-methylimidazo[1,2-a]pyridin-2-yl}-2H-chromen-2-one chemical structure, C17H11BrN2O2, CAS 337485-56-0
6-Bromo-3-{7-methylimidazo[1,2-a]pyridin-2-yl}-2H-chromen-2-one
CAS 337485-56-0C17H11BrN2O2
7-Hydroxy-3-(7-methylimidazo[1,2-a]pyridin-2-yl)chromen-2-one chemical structure, C17H12N2O3, CAS 300399-28-4
7-Hydroxy-3-(7-methylimidazo[1,2-a]pyridin-2-yl)chromen-2-one
CAS 300399-28-4C17H12N2O3
3-{6-Methylimidazo[1,2-a]pyridin-2-yl}-2H-chromen-2-one chemical structure, C17H12N2O2, CAS 326913-54-6
3-{6-Methylimidazo[1,2-a]pyridin-2-yl}-2H-chromen-2-one
CAS 326913-54-6C17H12N2O2
3-(3-Ethylimidazo[1,2-a]pyridin-2-yl)-8-methoxy-2H-chromen-2-one chemical structure, C19H16N2O3, CAS 1260929-34-7
3-(3-Ethylimidazo[1,2-a]pyridin-2-yl)-8-methoxy-2H-chromen-2-one
CAS 1260929-34-7C19H16N2O3
Methyl 2-(2-oxo-2H-chromen-3-yl)imidazo[1,2-a]pyridine-8-carboxylate chemical structure, C18H12N2O4, CAS 1325305-54-1
Methyl 2-(2-oxo-2H-chromen-3-yl)imidazo[1,2-a]pyridine-8-carboxylate
CAS 1325305-54-1C18H12N2O4
3-(6-Fluoroimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one chemical structure, C16H9FN2O2, CAS 1638736-30-7
3-(6-Fluoroimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one
CAS 1638736-30-7C16H9FN2O2
7-Fluoro-3-(8-fluoro-6-methylimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one chemical structure, C17H10F2N2O2, CAS 1446333-80-7
7-Fluoro-3-(8-fluoro-6-methylimidazo[1,2-a]pyridin-2-yl)-2H-chromen-2-one
CAS 1446333-80-7C17H10F2N2O2