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Murcko scaffold

RefChem:381445 scaffold

46 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
20
Chemicals
46
With full pages
21
Scaffold SMILES

O=c1oc2ccccc2cc1-c1nc2ccccc2[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the RefChem:381445 page
Murcko scaffold O=c1oc2ccccc2cc1-c1nc2ccccc2[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 46 of 46 chemicals

Coumarin 7 chemical structure, C20H19N3O2, CAS 27425-55-4
Coumarin 7
CAS 27425-55-4C20H19N3O2
Coumarin 30 chemical structure, C21H21N3O2, CAS 41044-12-6
Coumarin 30
CAS 41044-12-6C21H21N3O2
1H-Benzimidazolium, 2-(7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-, methyl sulfate (1:1) chemical structure, C23H27N3O6S, CAS 35869-60-4
1H-Benzimidazolium, 2-(7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-, methyl sulfate (1:1)
CAS 35869-60-4C23H27N3O6S
1H-Benzimidazolium, 2-(7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-, chloride (1:1) chemical structure, C22H24ClN3O2, CAS 29556-33-0
1H-Benzimidazolium, 2-(7-(diethylamino)-2-oxo-2H-1-benzopyran-3-yl)-1,3-dimethyl-, chloride (1:1)
CAS 29556-33-0C22H24ClN3O2
3-(1H-Benzimidazol-2-yl)-6,8-dichlorochromen-2-one chemical structure, C16H8Cl2N2O2, CAS 305865-15-0
3-(1H-Benzimidazol-2-yl)-6,8-dichlorochromen-2-one
CAS 305865-15-0C16H8Cl2N2O2
7-Methoxy-3-(1-methyl-1H-benzoimidazol-2-yl)-chromen-2-one chemical structure, C18H14N2O3, CAS 299953-22-3
7-Methoxy-3-(1-methyl-1H-benzoimidazol-2-yl)-chromen-2-one
CAS 299953-22-3C18H14N2O3
3-(5-Methyl-1H-benzimidazol-2-yl)chromen-2-one chemical structure, C17H12N2O2, CAS 59565-27-4
3-(5-Methyl-1H-benzimidazol-2-yl)chromen-2-one
CAS 59565-27-4C17H12N2O2
3-(1H-Benzimidazol-2-yl)-6-bromo-2H-chromen-2-one chemical structure, C16H9BrN2O2, CAS 143376-72-1
3-(1H-Benzimidazol-2-yl)-6-bromo-2H-chromen-2-one
CAS 143376-72-1C16H9BrN2O2
3-(1-Methyl-1H-benzimidazol-2-yl)-2-oxo-2H-chromen-7-yl propanoate chemical structure, C20H16N2O4, CAS 610758-23-1
3-(1-Methyl-1H-benzimidazol-2-yl)-2-oxo-2H-chromen-7-yl propanoate
CAS 610758-23-1C20H16N2O4
3-(1-Methyl-1H-benzo[d]imidazol-2-yl)-2-oxo-2H-chromen-7-yl acetate chemical structure, C19H14N2O4, CAS 300828-07-3
3-(1-Methyl-1H-benzo[d]imidazol-2-yl)-2-oxo-2H-chromen-7-yl acetate
CAS 300828-07-3C19H14N2O4
3-(1H-Benzimidazol-2-yl)-6-methyl-2H-chromen-2-one chemical structure, C17H12N2O2, CAS 428846-78-0
3-(1H-Benzimidazol-2-yl)-6-methyl-2H-chromen-2-one
CAS 428846-78-0C17H12N2O2
RefChem:381445 chemical structure, C16H10N2O2, CAS 1032-97-9
RefChem:381445
CAS 1032-97-9C16H10N2O2
6-Chloro-3-(1-methylbenzimidazol-2-yl)chromen-2-one chemical structure, C17H11ClN2O2, CAS 330188-93-7
6-Chloro-3-(1-methylbenzimidazol-2-yl)chromen-2-one
CAS 330188-93-7C17H11ClN2O2
3-(1H-Benzoimidazol-2-yl)-6-methoxy-chromen-2-one chemical structure, C17H12N2O3, CAS 245072-46-2
3-(1H-Benzoimidazol-2-yl)-6-methoxy-chromen-2-one
CAS 245072-46-2C17H12N2O3
3-(1H-1,3-Benzodiazol-2-yl)-7-methoxy-2H-chromen-2-one chemical structure, C17H12N2O3, CAS 93326-79-5
3-(1H-1,3-Benzodiazol-2-yl)-7-methoxy-2H-chromen-2-one
CAS 93326-79-5C17H12N2O3
3-(1H-Benzoimidazol-2-yl)-8-methoxy-chromen-2-one chemical structure, C17H12N2O3, CAS 293760-14-2
3-(1H-Benzoimidazol-2-yl)-8-methoxy-chromen-2-one
CAS 293760-14-2C17H12N2O3
3-(1-Methylbenzimidazol-2-yl)chromen-2-one chemical structure, C17H12N2O2, CAS 83520-72-3
3-(1-Methylbenzimidazol-2-yl)chromen-2-one
CAS 83520-72-3C17H12N2O2
3-(1H-Benzimidazol-2-yl)-8-ethoxy-2H-chromen-2-one chemical structure, C18H14N2O3, CAS 314048-15-2
3-(1H-Benzimidazol-2-yl)-8-ethoxy-2H-chromen-2-one
CAS 314048-15-2C18H14N2O3
3-(1H-Benzimidazol-2-yl)-6,8-dibromochromen-2-one chemical structure, C16H8Br2N2O2, CAS 143376-73-2
3-(1H-Benzimidazol-2-yl)-6,8-dibromochromen-2-one
CAS 143376-73-2C16H8Br2N2O2
[3-(1-Methylbenzimidazol-2-yl)-2-oxochromen-7-yl] 2,2-dimethylpropanoate chemical structure, C22H20N2O4, CAS 578699-45-3
[3-(1-Methylbenzimidazol-2-yl)-2-oxochromen-7-yl] 2,2-dimethylpropanoate
CAS 578699-45-3C22H20N2O4
Ethyl 2-((3-(1H-benzo[d]imidazol-2-yl)-2-oxo-2H-chromen-7-yl)oxy)acetate chemical structure, C20H16N2O5, CAS 6238-97-7
Ethyl 2-((3-(1H-benzo[d]imidazol-2-yl)-2-oxo-2H-chromen-7-yl)oxy)acetate
CAS 6238-97-7C20H16N2O5
3-(1-Methyl-1H-benzo[d]imidazol-2-yl)-2-oxo-2H-chromen-7-yl methanesulfonate chemical structure, C18H14N2O5S, CAS 299953-18-7
3-(1-Methyl-1H-benzo[d]imidazol-2-yl)-2-oxo-2H-chromen-7-yl methanesulfonate
CAS 299953-18-7C18H14N2O5S
6-Bromo-3-(6-methyl-1H-benzimidazol-2-yl)-2H-chromen-2-one chemical structure, C17H11BrN2O2, CAS 143376-74-3
6-Bromo-3-(6-methyl-1H-benzimidazol-2-yl)-2H-chromen-2-one
CAS 143376-74-3C17H11BrN2O2
3-(5-Chloro-1H-benzimidazol-2-yl)-7-(diethylamino)-2H-chromen-2-one chemical structure, C20H18ClN3O2, CAS 53350-30-4
3-(5-Chloro-1H-benzimidazol-2-yl)-7-(diethylamino)-2H-chromen-2-one
CAS 53350-30-4C20H18ClN3O2