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Murcko scaffold

Octahydroindolizin-3-one scaffold

49 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
49
With full pages
3
Scaffold SMILES

O=C1CCC2CCCCN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Octahydroindolizin-3-one page
Murcko scaffold O=C1CCC2CCCCN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 49 chemicals

O-[(5R,7R,8aR)-3-oxo-5-propyl-2,5,6,7,8,8a-hexahydro-1H-indolizin-7-yl] methylsulfanylmethanethioate chemical structure, C13H21NO2S2, CAS 82979-14-4
O-[(5R,7R,8aR)-3-oxo-5-propyl-2,5,6,7,8,8a-hexahydro-1H-indolizin-7-yl] methylsulfanylmethanethioate
CAS 82979-14-4C13H21NO2S2
Octahydroindolizin-3-one chemical structure, C8H13NO, CAS 2740-00-3
Octahydroindolizin-3-one
CAS 2740-00-3C8H13NO
(S)-Hexahydroindolizin-3(2H)-one chemical structure, C8H13NO, CAS 139894-04-5
(S)-Hexahydroindolizin-3(2H)-one
CAS 139894-04-5C8H13NO
(2R,5S,6R,7R,8R,8aS)-2,6,7,8-Tetrahydroxy-5-methyl-2,5,6,7,8,8a-hexahydro-1H-indolizin-3-one chemical structure, C9H15NO5, CAS 244612-35-9
(2R,5S,6R,7R,8R,8aS)-2,6,7,8-Tetrahydroxy-5-methyl-2,5,6,7,8,8a-hexahydro-1H-indolizin-3-one
CAS 244612-35-9C9H15NO5
(6S,7S,8S,8aS)-6,7,8-Trihydroxy-8a-methoxy-1,2,5,6,7,8-hexahydroindolizin-3-one chemical structure, C9H15NO5, CAS 288622-62-8
(6S,7S,8S,8aS)-6,7,8-Trihydroxy-8a-methoxy-1,2,5,6,7,8-hexahydroindolizin-3-one
CAS 288622-62-8C9H15NO5
3(2H)-Indolizinone, hexahydro-8-methyl-, cis- chemical structure, C9H15NO, CAS 80664-52-4
3(2H)-Indolizinone, hexahydro-8-methyl-, cis-
CAS 80664-52-4C9H15NO
Trans-8-methylhexahydroindolizin-3(2H)-one chemical structure, C9H15NO
Trans-8-methylhexahydroindolizin-3(2H)-one
C9H15NO
3-Oxo-(-)-lentiginosine chemical structure, C8H13NO3, CAS 160169-49-3
3-Oxo-(-)-lentiginosine
CAS 160169-49-3C8H13NO3
7-Hydroxyhexahydroindolizin-3(2H)-one chemical structure, C8H13NO2, CAS 2408770-49-8
7-Hydroxyhexahydroindolizin-3(2H)-one
CAS 2408770-49-8C8H13NO2
2-(1-Hydroxyethyl)hexahydroindolizin-3(2H)-one chemical structure, C10H17NO2, CAS 81199-70-4
2-(1-Hydroxyethyl)hexahydroindolizin-3(2H)-one
CAS 81199-70-4C10H17NO2
Hexahydro-8-methyl-3(2H)-indolizinone chemical structure, C9H15NO, CAS 344294-74-2
Hexahydro-8-methyl-3(2H)-indolizinone
CAS 344294-74-2C9H15NO
(R)-Hexahydroindolizin-3(2H)-one chemical structure, C8H13NO, CAS 142796-65-4
(R)-Hexahydroindolizin-3(2H)-one
CAS 142796-65-4C8H13NO
6-Bromohexahydroindolizin-3(2H)-one chemical structure, C8H12BrNO, CAS 1824475-81-1
6-Bromohexahydroindolizin-3(2H)-one
CAS 1824475-81-1C8H12BrNO
Methyl 3-oxooctahydroindolizine-6-carboxylate chemical structure, C10H15NO3, CAS 1620675-65-1
Methyl 3-oxooctahydroindolizine-6-carboxylate
CAS 1620675-65-1C10H15NO3
(5R,8aR)-3-Oxooctahydroindolizine-5-carbonitrile chemical structure, C9H12N2O, CAS 934561-08-7
(5R,8aR)-3-Oxooctahydroindolizine-5-carbonitrile
CAS 934561-08-7C9H12N2O
rel-(5R,8aR)-3-Oxooctahydro-5-indoliZinecarboxylic acid chemical structure, C9H13NO3, CAS 934561-09-8
rel-(5R,8aR)-3-Oxooctahydro-5-indoliZinecarboxylic acid
CAS 934561-09-8C9H13NO3
(5R,7S,8aS)-7-Hydroxy-5-propylhexahydroindolizin-3(2H)-one chemical structure, C11H19NO2, CAS 960049-54-1
(5R,7S,8aS)-7-Hydroxy-5-propylhexahydroindolizin-3(2H)-one
CAS 960049-54-1C11H19NO2
1-Amino-3-oxo-octahydro-indolizine-2-carboxylic acid ethyl ester chemical structure, C11H18N2O3, CAS 1217860-86-0
1-Amino-3-oxo-octahydro-indolizine-2-carboxylic acid ethyl ester
CAS 1217860-86-0C11H18N2O3
1-Hydroxy-3-oxo-octahydro-indolizine-2-carboxylic acid ethyl ester chemical structure, C11H17NO4, CAS 1217673-51-2
1-Hydroxy-3-oxo-octahydro-indolizine-2-carboxylic acid ethyl ester
CAS 1217673-51-2C11H17NO4
8-Amino-3-oxooctahydroindolizine-2-carboxylic acid chemical structure, C9H14N2O3, CAS 349101-84-4
8-Amino-3-oxooctahydroindolizine-2-carboxylic acid
CAS 349101-84-4C9H14N2O3
8-Amino-3-oxooctahydroindolizine-1-carboxylic acid chemical structure, C9H14N2O3, CAS 349101-83-3
8-Amino-3-oxooctahydroindolizine-1-carboxylic acid
CAS 349101-83-3C9H14N2O3
(2S,8S,8AR)-8-amino-3-oxooctahydroindolizine-2-carboxylic acid chemical structure, C9H14N2O3, CAS 137038-27-8
(2S,8S,8AR)-8-amino-3-oxooctahydroindolizine-2-carboxylic acid
CAS 137038-27-8C9H14N2O3
(2R,8S,8AR)-8-amino-3-oxooctahydroindolizine-2-carboxylic acid chemical structure, C9H14N2O3, CAS 137002-58-5
(2R,8S,8AR)-8-amino-3-oxooctahydroindolizine-2-carboxylic acid
CAS 137002-58-5C9H14N2O3
(7S,8aS)-7-Fluoro-2,5,6,7,8,8a-hexahydro-1H-indolizin-3-one chemical structure, C8H12FNO, CAS 148855-30-5
(7S,8aS)-7-Fluoro-2,5,6,7,8,8a-hexahydro-1H-indolizin-3-one
CAS 148855-30-5C8H12FNO