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Murcko scaffold

Ring system with 3 rings and 16 atoms

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
30
With full pages
10
Scaffold SMILES

O=c1[nH]c2cncnc2n1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2cncnc2n1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

9-(3,4-Dimethylphenyl)-8,9-dihydro-8-oxo-7H-purine-6-carboxamide chemical structure, C14H13N5O2, CAS 898447-01-3
9-(3,4-Dimethylphenyl)-8,9-dihydro-8-oxo-7H-purine-6-carboxamide
CAS 898447-01-3C14H13N5O2
9-(2-Fluorophenyl)-8-oxo-2-propan-2-yl-7H-purine-6-carboxamide chemical structure, C15H14FN5O2, CAS 898446-06-5
9-(2-Fluorophenyl)-8-oxo-2-propan-2-yl-7H-purine-6-carboxamide
CAS 898446-06-5C15H14FN5O2
9-(3,4-Dimethylphenyl)-2-isopropyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C17H19N5O2, CAS 898446-82-7
9-(3,4-Dimethylphenyl)-2-isopropyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 898446-82-7C17H19N5O2
9-(2,4-Dimethoxyphenyl)-8-oxo-2-propan-2-yl-7H-purine-6-carboxamide chemical structure, C17H19N5O4, CAS 904268-59-3
9-(2,4-Dimethoxyphenyl)-8-oxo-2-propan-2-yl-7H-purine-6-carboxamide
CAS 904268-59-3C17H19N5O4
2-Butyl-9-(3,4-dimethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H21N5O4, CAS 900010-34-6
2-Butyl-9-(3,4-dimethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 900010-34-6C18H21N5O4
9-(3,4-Dimethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C20H25N5O4, CAS 899741-73-2
9-(3,4-Dimethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899741-73-2C20H25N5O4
9-(3,4-Dimethoxyphenyl)-8-oxo-2-(pentan-3-yl)-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C19H23N5O4, CAS 899970-62-8
9-(3,4-Dimethoxyphenyl)-8-oxo-2-(pentan-3-yl)-8,9-dihydro-7H-purine-6-carboxamide
CAS 899970-62-8C19H23N5O4
2-Butyl-9-(2,4-dimethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H21N5O4, CAS 942010-16-4
2-Butyl-9-(2,4-dimethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 942010-16-4C18H21N5O4
9-(2,4-Dimethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C20H25N5O4, CAS 941885-32-1
9-(2,4-Dimethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 941885-32-1C20H25N5O4
2-Ethyl-9-(2-fluorophenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C14H12FN5O2, CAS 899970-63-9
2-Ethyl-9-(2-fluorophenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899970-63-9C14H12FN5O2
2-Butyl-9-(2-fluorophenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C16H16FN5O2, CAS 900010-40-4
2-Butyl-9-(2-fluorophenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 900010-40-4C16H16FN5O2
9-(2-Fluorophenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H20FN5O2, CAS 899741-77-6
9-(2-Fluorophenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899741-77-6C18H20FN5O2
2-Butyl-9-(4-ethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H21N5O3, CAS 899970-64-0
2-Butyl-9-(4-ethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899970-64-0C18H21N5O3
9-(4-Ethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C20H25N5O3, CAS 900010-43-7
9-(4-Ethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 900010-43-7C20H25N5O3
9-(4-Ethoxyphenyl)-8-oxo-2-(pentan-3-yl)-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C19H23N5O3, CAS 899741-79-8
9-(4-Ethoxyphenyl)-8-oxo-2-(pentan-3-yl)-8,9-dihydro-7H-purine-6-carboxamide
CAS 899741-79-8C19H23N5O3
2-Butyl-9-(3,4-dimethylphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H21N5O2, CAS 899970-65-1
2-Butyl-9-(3,4-dimethylphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899970-65-1C18H21N5O2
9-(3,4-Dimethylphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C20H25N5O2, CAS 900010-46-0
9-(3,4-Dimethylphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 900010-46-0C20H25N5O2
2-Butyl-9-(3-methoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C17H19N5O3, CAS 899970-91-3
2-Butyl-9-(3-methoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899970-91-3C17H19N5O3
2-Hexyl-9-(3-methoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C19H23N5O3, CAS 900010-85-7
2-Hexyl-9-(3-methoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 900010-85-7C19H23N5O3
9-(3-Methoxyphenyl)-8-oxo-2-(pentan-3-yl)-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H21N5O3, CAS 899742-15-5
9-(3-Methoxyphenyl)-8-oxo-2-(pentan-3-yl)-8,9-dihydro-7H-purine-6-carboxamide
CAS 899742-15-5C18H21N5O3
9-(3-Methoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C13H11N5O3, CAS 942010-20-0
9-(3-Methoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 942010-20-0C13H11N5O3
9-(2-Ethoxyphenyl)-2-ethyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C16H17N5O3, CAS 900010-88-0
9-(2-Ethoxyphenyl)-2-ethyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 900010-88-0C16H17N5O3
2-Butyl-9-(2-ethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C18H21N5O3, CAS 899742-44-0
2-Butyl-9-(2-ethoxyphenyl)-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899742-44-0C18H21N5O3
9-(2-Ethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide chemical structure, C20H25N5O3, CAS 899971-19-8
9-(2-Ethoxyphenyl)-2-hexyl-8-oxo-8,9-dihydro-7H-purine-6-carboxamide
CAS 899971-19-8C20H25N5O3