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Murcko scaffold

1-Benzhydryl-4-benzoylpiperazine scaffold

43 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
43
With full pages
2
Scaffold SMILES

O=C(c1ccccc1)N1CCN(C(c2ccccc2)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzhydryl-4-benzoylpiperazine page
Murcko scaffold O=C(c1ccccc1)N1CCN(C(c2ccccc2)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 43 of 43 chemicals

1-Benzhydryl-4-(3,4,5-triethoxybenzoyl)piperazine chemical structure, C30H36N2O4, CAS 329223-08-7
1-Benzhydryl-4-(3,4,5-triethoxybenzoyl)piperazine
CAS 329223-08-7C30H36N2O4
(4-Benzhydrylpiperazin-1-yl)-(2-chloro-4-nitrophenyl)methanone chemical structure, C24H22ClN3O3, CAS 543708-05-0
(4-Benzhydrylpiperazin-1-yl)-(2-chloro-4-nitrophenyl)methanone
CAS 543708-05-0C24H22ClN3O3
1-Benzhydryl-4-(3,4-dimethoxybenzoyl)piperazine chemical structure, C26H28N2O3, CAS 325472-18-2
1-Benzhydryl-4-(3,4-dimethoxybenzoyl)piperazine
CAS 325472-18-2C26H28N2O3
(4-Benzhydrylpiperazin-1-yl)-(4-tert-butylphenyl)methanone chemical structure, C28H32N2O, CAS 312588-66-2
(4-Benzhydrylpiperazin-1-yl)-(4-tert-butylphenyl)methanone
CAS 312588-66-2C28H32N2O
1-Benzhydryl-4-(2-fluorobenzoyl)piperazine chemical structure, C24H23FN2O, CAS 328269-97-2
1-Benzhydryl-4-(2-fluorobenzoyl)piperazine
CAS 328269-97-2C24H23FN2O
1-Benzhydryl-4-(2-methylbenzoyl)piperazine chemical structure, C25H26N2O, CAS 353467-15-9
1-Benzhydryl-4-(2-methylbenzoyl)piperazine
CAS 353467-15-9C25H26N2O
(4-Benzhydrylpiperazin-1-yl)-(4-methoxyphenyl)methanone chemical structure, C25H26N2O2, CAS 294196-25-1
(4-Benzhydrylpiperazin-1-yl)-(4-methoxyphenyl)methanone
CAS 294196-25-1C25H26N2O2
1-Benzhydryl-4-(3,5-dimethoxybenzoyl)piperazine chemical structure, C26H28N2O3, CAS 331987-46-3
1-Benzhydryl-4-(3,5-dimethoxybenzoyl)piperazine
CAS 331987-46-3C26H28N2O3
1-Benzhydryl-4-(3-methoxybenzoyl)piperazine chemical structure, C25H26N2O2, CAS 325472-17-1
1-Benzhydryl-4-(3-methoxybenzoyl)piperazine
CAS 325472-17-1C25H26N2O2
1-Benzhydryl-4-(3-fluorobenzoyl)piperazine chemical structure, C24H23FN2O, CAS 328906-37-2
1-Benzhydryl-4-(3-fluorobenzoyl)piperazine
CAS 328906-37-2C24H23FN2O
1-Benzhydryl-4-(4-fluorobenzoyl)piperazine chemical structure, C24H23FN2O, CAS 328906-41-8
1-Benzhydryl-4-(4-fluorobenzoyl)piperazine
CAS 328906-41-8C24H23FN2O
1-Benzhydryl-4-(2-bromobenzoyl)piperazine chemical structure, C24H23BrN2O, CAS 314055-81-7
1-Benzhydryl-4-(2-bromobenzoyl)piperazine
CAS 314055-81-7C24H23BrN2O
1-Benzhydryl-4-(2-methoxybenzoyl)piperazine chemical structure, C25H26N2O2, CAS 353466-81-6
1-Benzhydryl-4-(2-methoxybenzoyl)piperazine
CAS 353466-81-6C25H26N2O2
(4-Benzhydrylpiperazin-1-yl)-(5-chloro-2-nitrophenyl)methanone chemical structure, C24H22ClN3O3, CAS 540801-03-4
(4-Benzhydrylpiperazin-1-yl)-(5-chloro-2-nitrophenyl)methanone
CAS 540801-03-4C24H22ClN3O3
2-{[4-(Diphenylmethyl)piperazinyl]carbonyl}benzoic acid chemical structure, C25H24N2O3, CAS 681800-92-0
2-{[4-(Diphenylmethyl)piperazinyl]carbonyl}benzoic acid
CAS 681800-92-0C25H24N2O3
1-Benzhydryl-4-benzoylpiperazine chemical structure, C24H24N2O, CAS 70713-46-1
1-Benzhydryl-4-benzoylpiperazine
CAS 70713-46-1C24H24N2O
1-(3-Chlorobenzoyl)-4-(diphenylmethyl)piperazine chemical structure, C24H23ClN2O, CAS 425654-61-1
1-(3-Chlorobenzoyl)-4-(diphenylmethyl)piperazine
CAS 425654-61-1C24H23ClN2O
2,6-Difluorophenyl 4-(diphenylmethyl)piperazinyl ketone chemical structure, C24H22F2N2O, CAS 496054-70-7
2,6-Difluorophenyl 4-(diphenylmethyl)piperazinyl ketone
CAS 496054-70-7C24H22F2N2O
(2-Aminophenyl)(4-benzhydryl-1-piperazinyl)-methanone chemical structure, C24H25N3O, CAS 184781-00-8
(2-Aminophenyl)(4-benzhydryl-1-piperazinyl)-methanone
CAS 184781-00-8C24H25N3O
(4-Benzhydrylpiperazin-1-yl)-(3-chloro-4-methylphenyl)methanone chemical structure, C25H25ClN2O, CAS 431928-66-4
(4-Benzhydrylpiperazin-1-yl)-(3-chloro-4-methylphenyl)methanone
CAS 431928-66-4C25H25ClN2O
(4-Benzhydrylpiperazin-1-yl)-(4-methyl-3-nitrophenyl)methanone chemical structure, C25H25N3O3, CAS 428497-33-0
(4-Benzhydrylpiperazin-1-yl)-(4-methyl-3-nitrophenyl)methanone
CAS 428497-33-0C25H25N3O3
1-Benzhydryl-4-(2-iodobenzoyl)piperazine chemical structure, C24H23IN2O, CAS 425651-79-2
1-Benzhydryl-4-(2-iodobenzoyl)piperazine
CAS 425651-79-2C24H23IN2O
4-(Diphenylmethyl)piperazinyl 4-bromophenyl ketone chemical structure, C24H23BrN2O, CAS 324068-21-5
4-(Diphenylmethyl)piperazinyl 4-bromophenyl ketone
CAS 324068-21-5C24H23BrN2O
(4-Chloro-2-nitrophenyl)[4-(diphenylmethyl)piperazin-1-yl]methanone chemical structure, C24H22ClN3O3, CAS 5697-17-6
(4-Chloro-2-nitrophenyl)[4-(diphenylmethyl)piperazin-1-yl]methanone
CAS 5697-17-6C24H22ClN3O3