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Murcko scaffold

1-Benzhydryl-4-benzylpiperazine scaffold

66 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
66
With full pages
13
Scaffold SMILES

c1ccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzhydryl-4-benzylpiperazine page
Murcko scaffold c1ccc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 66 chemicals

Lomerizine chemical structure, C27H30F2N2O3, CAS 101477-55-8
Lomerizine
CAS 101477-55-8C27H30F2N2O3
Meclizine chemical structure, C25H27ClN2, CAS 569-65-3
Meclizine
CAS 569-65-3C25H27ClN2
Buclizine chemical structure, C28H33ClN2, CAS 82-95-1
Buclizine
CAS 82-95-1C28H33ClN2
Meclozine dihydrochloride chemical structure, C25H29Cl3N2, CAS 1104-22-9
Meclozine dihydrochloride
CAS 1104-22-9C25H29Cl3N2
Buclizine hydrochloride chemical structure, C28H35Cl3N2, CAS 129-74-8
Buclizine hydrochloride
CAS 129-74-8C28H35Cl3N2
Meclizine monohydrochloride chemical structure, C25H28Cl2N2, CAS 410538-37-3
Meclizine monohydrochloride
CAS 410538-37-3C25H28Cl2N2
Meclizine hydrochloride mixture with pyridoxine hydrochloride chemical structure, C33H41Cl4N3O3, CAS 56575-29-2
Meclizine hydrochloride mixture with pyridoxine hydrochloride
CAS 56575-29-2C33H41Cl4N3O3
Lomerizine hydrochloride chemical structure, C27H32Cl2F2N2O3, CAS 101477-54-7
Lomerizine hydrochloride
CAS 101477-54-7C27H32Cl2F2N2O3
3-Pyridinecarboxylic acid, mixt. with 1-((4-chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)piperazine dihydrochloride chemical structure, C31H34Cl3N3O2, CAS 8064-07-1
3-Pyridinecarboxylic acid, mixt. with 1-((4-chlorophenyl)phenylmethyl)-4-((3-methylphenyl)methyl)piperazine dihydrochloride
CAS 8064-07-1C31H34Cl3N3O2
Belarizine chemical structure, C24H26N2O, CAS 52395-99-0
Belarizine
CAS 52395-99-0C24H26N2O
1-Benzhydryl-4-benzylpiperazine chemical structure, C24H26N2, CAS 97095-89-1
1-Benzhydryl-4-benzylpiperazine
CAS 97095-89-1C24H26N2
4-((4-(Diphenylmethyl)piperazin-1-yl)methyl)-N-methyl-2-nitroaniline chemical structure, C25H28N4O2, CAS 68740-15-8
4-((4-(Diphenylmethyl)piperazin-1-yl)methyl)-N-methyl-2-nitroaniline
CAS 68740-15-8C25H28N4O2
4-[[4-(Diphenylmethyl)piperazin-1-yl]methyl]-N-ethyl-2-nitroaniline chemical structure, C26H30N4O2, CAS 68740-16-9
4-[[4-(Diphenylmethyl)piperazin-1-yl]methyl]-N-ethyl-2-nitroaniline
CAS 68740-16-9C26H30N4O2
4-[[4-(Diphenylmethyl)piperazin-1-yl]methyl]-N-methylbenzene-1,2-diamine chemical structure, C25H30N4, CAS 68740-30-7
4-[[4-(Diphenylmethyl)piperazin-1-yl]methyl]-N-methylbenzene-1,2-diamine
CAS 68740-30-7C25H30N4
4-((4-(Diphenylmethyl)piperazin-1-yl)methyl)-N-ethylbenzene-1,2-diamine chemical structure, C26H32N4, CAS 68740-78-3
4-((4-(Diphenylmethyl)piperazin-1-yl)methyl)-N-ethylbenzene-1,2-diamine
CAS 68740-78-3C26H32N4
1-Benzhydryl-4-[(4-methoxy-3-nitrophenyl)methyl]piperazine chemical structure, C25H27N3O3, CAS 84255-06-1
1-Benzhydryl-4-[(4-methoxy-3-nitrophenyl)methyl]piperazine
CAS 84255-06-1C25H27N3O3
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-((2,4-dimethoxyphenyl)methyl)-, hydrochloride, hydrate (1:2:2) chemical structure, C26H30Cl2F2N2O2, CAS 101477-47-8
Piperazine, 1-(bis(4-fluorophenyl)methyl)-4-((2,4-dimethoxyphenyl)methyl)-, hydrochloride, hydrate (1:2:2)
CAS 101477-47-8C26H30Cl2F2N2O2
1-Benzhydryl-4-[4-(3-fluoropropoxy)benzyl]piperazine chemical structure, C27H31FN2O, CAS 477871-00-4
1-Benzhydryl-4-[4-(3-fluoropropoxy)benzyl]piperazine
CAS 477871-00-4C27H31FN2O
4-((4-Benzylpiperazin-1-yl)(4-chlorophenyl)methyl)-2,6-di-tert-butylphenol chemical structure, C32H41ClN2O, CAS 325474-13-3
4-((4-Benzylpiperazin-1-yl)(4-chlorophenyl)methyl)-2,6-di-tert-butylphenol
CAS 325474-13-3C32H41ClN2O
1-(Diphenylmethyl)-4-(4-methylbenzyl)piperazine chemical structure, C25H28N2, CAS 112291-99-3
1-(Diphenylmethyl)-4-(4-methylbenzyl)piperazine
CAS 112291-99-3C25H28N2
Vibazine chemical structure, C28H34Cl2N2, CAS 1230988-67-6
Vibazine
CAS 1230988-67-6C28H34Cl2N2
Piperazine, 1-((2,4-dimethoxyphenyl)methyl)-4-((4-fluorophenyl)phenylmethyl)-, (E)-2-butenedioate (1:1) chemical structure, C30H33FN2O6, CAS 101477-46-7
Piperazine, 1-((2,4-dimethoxyphenyl)methyl)-4-((4-fluorophenyl)phenylmethyl)-, (E)-2-butenedioate (1:1)
CAS 101477-46-7C30H33FN2O6
Piperazine, 1-((4-fluorophenyl)phenylmethyl)-4-((2,3,4-trimethoxyphenyl)methyl)-, (E)-2-butenedioate (1:1) chemical structure, C31H35FN2O7, CAS 101477-51-4
Piperazine, 1-((4-fluorophenyl)phenylmethyl)-4-((2,3,4-trimethoxyphenyl)methyl)-, (E)-2-butenedioate (1:1)
CAS 101477-51-4C31H35FN2O7
(S)-Meclizine chemical structure, C25H27ClN2, CAS 189298-47-3
(S)-Meclizine
CAS 189298-47-3C25H27ClN2