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Murcko scaffold

1-Benzhydryl-4-(phenylsulfonyl)piperazine scaffold

80 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
28
Chemicals
80
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CCN(C(c2ccccc2)c2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Benzhydryl-4-(phenylsulfonyl)piperazine page
Murcko scaffold O=S(=O)(c1ccccc1)N1CCN(C(c2ccccc2)c2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 80 chemicals

1-Benzhydryl-4-(2,3-dichloro-4-methoxyphenyl)sulfonylpiperazine chemical structure, C24H24Cl2N2O3S, CAS 663161-56-6
1-Benzhydryl-4-(2,3-dichloro-4-methoxyphenyl)sulfonylpiperazine
CAS 663161-56-6C24H24Cl2N2O3S
1-Benzhydryl-4-((2-fluorophenyl)sulfonyl)piperazine chemical structure, C23H23FN2O2S, CAS 667912-10-9
1-Benzhydryl-4-((2-fluorophenyl)sulfonyl)piperazine
CAS 667912-10-9C23H23FN2O2S
1-Benzhydryl-4-(2,6-dichlorophenyl)sulfonylpiperazine chemical structure, C23H22Cl2N2O2S, CAS 667912-11-0
1-Benzhydryl-4-(2,6-dichlorophenyl)sulfonylpiperazine
CAS 667912-11-0C23H22Cl2N2O2S
1-Benzhydryl-4-(3-chlorophenyl)sulfonylpiperazine chemical structure, C23H23ClN2O2S, CAS 667912-13-2
1-Benzhydryl-4-(3-chlorophenyl)sulfonylpiperazine
CAS 667912-13-2C23H23ClN2O2S
1-(3-Chloro-4-fluorobenzenesulfonyl)-4-(diphenylmethyl)piperazine chemical structure, C23H22ClFN2O2S, CAS 667912-14-3
1-(3-Chloro-4-fluorobenzenesulfonyl)-4-(diphenylmethyl)piperazine
CAS 667912-14-3C23H22ClFN2O2S
1-Benzhydryl-4-(3-methoxyphenyl)sulfonylpiperazine chemical structure, C24H26N2O3S, CAS 667912-15-4
1-Benzhydryl-4-(3-methoxyphenyl)sulfonylpiperazine
CAS 667912-15-4C24H26N2O3S
1-Benzhydryl-4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazine chemical structure, C27H32N2O2S, CAS 496013-67-3
1-Benzhydryl-4-(2,3,5,6-tetramethylphenyl)sulfonylpiperazine
CAS 496013-67-3C27H32N2O2S
1-Benzhydryl-4-(2,5-dimethoxyphenyl)sulfonylpiperazine chemical structure, C25H28N2O4S, CAS 420808-65-7
1-Benzhydryl-4-(2,5-dimethoxyphenyl)sulfonylpiperazine
CAS 420808-65-7C25H28N2O4S
1-(3,4-Dimethylbenzenesulfonyl)-4-(diphenylmethyl)piperazine chemical structure, C25H28N2O2S, CAS 419539-20-1
1-(3,4-Dimethylbenzenesulfonyl)-4-(diphenylmethyl)piperazine
CAS 419539-20-1C25H28N2O2S
1-(Diphenylmethyl)-4-[(4-methylphenyl)sulfonyl]piperazine chemical structure, C24H26N2O2S, CAS 324067-28-9
1-(Diphenylmethyl)-4-[(4-methylphenyl)sulfonyl]piperazine
CAS 324067-28-9C24H26N2O2S
1-Benzhydryl-4-(phenylsulfonyl)piperazine chemical structure, C23H24N2O2S, CAS 312282-48-7
1-Benzhydryl-4-(phenylsulfonyl)piperazine
CAS 312282-48-7C23H24N2O2S
1-((4-(Diphenylmethyl)piperazinyl)sulfonyl)-4-chlorobenzene chemical structure, C23H23ClN2O2S, CAS 312282-53-4
1-((4-(Diphenylmethyl)piperazinyl)sulfonyl)-4-chlorobenzene
CAS 312282-53-4C23H23ClN2O2S
1-Benzhydryl-4-((2-nitrophenyl)sulfonyl)piperazine chemical structure, C23H23N3O4S, CAS 325812-48-4
1-Benzhydryl-4-((2-nitrophenyl)sulfonyl)piperazine
CAS 325812-48-4C23H23N3O4S
1-(Diphenylmethyl)-4-[(2,4,6-trimethylphenyl)sulfonyl]piperazine chemical structure, C26H30N2O2S, CAS 5854-47-7
1-(Diphenylmethyl)-4-[(2,4,6-trimethylphenyl)sulfonyl]piperazine
CAS 5854-47-7C26H30N2O2S
1-Benzhydryl-4-((4-chloro-3-methylphenyl)sulfonyl)piperazine chemical structure, C24H25ClN2O2S, CAS 325813-89-6
1-Benzhydryl-4-((4-chloro-3-methylphenyl)sulfonyl)piperazine
CAS 325813-89-6C24H25ClN2O2S
1-(Diphenylmethyl)-4-(3-methylbenzenesulfonyl)piperazine chemical structure, C24H26N2O2S, CAS 670272-24-9
1-(Diphenylmethyl)-4-(3-methylbenzenesulfonyl)piperazine
CAS 670272-24-9C24H26N2O2S
1-(2,5-Dichloro-4-methoxybenzenesulfonyl)-4-(diphenylmethyl)piperazine chemical structure, C24H24Cl2N2O3S, CAS 433948-63-1
1-(2,5-Dichloro-4-methoxybenzenesulfonyl)-4-(diphenylmethyl)piperazine
CAS 433948-63-1C24H24Cl2N2O3S
1-(Diphenylmethyl)-4-(2,3,4-trimethylbenzenesulfonyl)piperazine chemical structure, C26H30N2O2S, CAS 433974-14-2
1-(Diphenylmethyl)-4-(2,3,4-trimethylbenzenesulfonyl)piperazine
CAS 433974-14-2C26H30N2O2S
6-[(4-Benzhydryl-1-piperazinyl)sulfonyl]-2,3-dichlorophenyl methyl ether chemical structure, C24H24Cl2N2O3S, CAS 428471-51-6
6-[(4-Benzhydryl-1-piperazinyl)sulfonyl]-2,3-dichlorophenyl methyl ether
CAS 428471-51-6C24H24Cl2N2O3S
2-[(4-Benzhydryl-1-piperazinyl)sulfonyl]-5-methylphenyl methyl ether chemical structure, C25H28N2O3S, CAS 428474-30-0
2-[(4-Benzhydryl-1-piperazinyl)sulfonyl]-5-methylphenyl methyl ether
CAS 428474-30-0C25H28N2O3S
1-(4-Chloro-3-methoxybenzenesulfonyl)-4-(diphenylmethyl)piperazine chemical structure, C24H25ClN2O3S, CAS 428498-77-5
1-(4-Chloro-3-methoxybenzenesulfonyl)-4-(diphenylmethyl)piperazine
CAS 428498-77-5C24H25ClN2O3S
1-Benzhydryl-4-(5-bromo-2-methylphenyl)sulfonylpiperazine chemical structure, C24H25BrN2O2S, CAS 424796-52-1
1-Benzhydryl-4-(5-bromo-2-methylphenyl)sulfonylpiperazine
CAS 424796-52-1C24H25BrN2O2S
1-Benzhydryl-4-(4-methoxyphenyl)sulfonylpiperazine chemical structure, C24H26N2O3S, CAS 359023-54-4
1-Benzhydryl-4-(4-methoxyphenyl)sulfonylpiperazine
CAS 359023-54-4C24H26N2O3S
4-[(4-Benzhydryl-1-piperazinyl)sulfonyl]aniline chemical structure, C23H25N3O2S, CAS 20127-97-3
4-[(4-Benzhydryl-1-piperazinyl)sulfonyl]aniline
CAS 20127-97-3C23H25N3O2S