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Murcko scaffold

Ring system with 4 rings and 24 atoms

19 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
19
With full pages
7
Scaffold SMILES

c1ccc(OCc2ccc(-c3ncc(N4CCCCC4)o3)o2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(OCc2ccc(-c3ncc(N4CCCCC4)o3)o2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

2-(5-(Phenoxymethyl)furan-2-yl)-5-(piperidin-1-yl)oxazole-4-carbonitrile chemical structure, C20H19N3O3, CAS 931704-10-8
2-(5-(Phenoxymethyl)furan-2-yl)-5-(piperidin-1-yl)oxazole-4-carbonitrile
CAS 931704-10-8C20H19N3O3
5-(4-Methylpiperidin-1-yl)-2-[5-(phenoxymethyl)furan-2-yl]-1,3-oxazole-4-carbonitrile chemical structure, C21H21N3O3, CAS 946378-30-9
5-(4-Methylpiperidin-1-yl)-2-[5-(phenoxymethyl)furan-2-yl]-1,3-oxazole-4-carbonitrile
CAS 946378-30-9C21H21N3O3
5-(4-Methylpiperidin-1-yl)-2-(5-((p-tolyloxy)methyl)furan-2-yl)oxazole-4-carbonitrile chemical structure, C22H23N3O3, CAS 931317-38-3
5-(4-Methylpiperidin-1-yl)-2-(5-((p-tolyloxy)methyl)furan-2-yl)oxazole-4-carbonitrile
CAS 931317-38-3C22H23N3O3
2-(5-((4-Chlorophenoxy)methyl)furan-2-yl)-5-(piperidin-1-yl)oxazole-4-carbonitrile chemical structure, C20H18ClN3O3, CAS 931968-16-0
2-(5-((4-Chlorophenoxy)methyl)furan-2-yl)-5-(piperidin-1-yl)oxazole-4-carbonitrile
CAS 931968-16-0C20H18ClN3O3
2-{5-[(4-Chlorophenoxy)methyl]furan-2-yl}-5-(4-methylpiperidin-1-yl)-1,3-oxazole-4-carbonitrile chemical structure, C21H20ClN3O3, CAS 931704-47-1
2-{5-[(4-Chlorophenoxy)methyl]furan-2-yl}-5-(4-methylpiperidin-1-yl)-1,3-oxazole-4-carbonitrile
CAS 931704-47-1C21H20ClN3O3
1-(2-(5-((4-Chlorophenoxy)methyl)furan-2-yl)-4-cyanooxazol-5-yl)piperidine-4-carboxamide chemical structure, C21H19ClN4O4, CAS 931968-25-1
1-(2-(5-((4-Chlorophenoxy)methyl)furan-2-yl)-4-cyanooxazol-5-yl)piperidine-4-carboxamide
CAS 931968-25-1C21H19ClN4O4
2-(5-((4-Methoxyphenoxy)methyl)furan-2-yl)-5-(piperidin-1-yl)oxazole-4-carbonitrile chemical structure, C21H21N3O4, CAS 941929-27-7
2-(5-((4-Methoxyphenoxy)methyl)furan-2-yl)-5-(piperidin-1-yl)oxazole-4-carbonitrile
CAS 941929-27-7C21H21N3O4
2-(5-((4-Methoxyphenoxy)methyl)furan-2-yl)-5-(4-methylpiperidin-1-yl)oxazole-4-carbonitrile chemical structure, C22H23N3O4, CAS 941969-04-6
2-(5-((4-Methoxyphenoxy)methyl)furan-2-yl)-5-(4-methylpiperidin-1-yl)oxazole-4-carbonitrile
CAS 941969-04-6C22H23N3O4
1-(4-Cyano-2-{5-[(4-methoxyphenoxy)methyl]furan-2-yl}-1,3-oxazol-5-yl)piperidine-4-carboxamide chemical structure, C22H22N4O5, CAS 946378-42-3
1-(4-Cyano-2-{5-[(4-methoxyphenoxy)methyl]furan-2-yl}-1,3-oxazol-5-yl)piperidine-4-carboxamide
CAS 946378-42-3C22H22N4O5
1-(4-Cyano-2-{5-[(3-methylphenoxy)methyl]furan-2-yl}-1,3-oxazol-5-yl)piperidine-4-carboxamide chemical structure, C22H22N4O4, CAS 931749-15-4
1-(4-Cyano-2-{5-[(3-methylphenoxy)methyl]furan-2-yl}-1,3-oxazol-5-yl)piperidine-4-carboxamide
CAS 931749-15-4C22H22N4O4
5-(Piperidin-1-yl)-2-(5-((o-tolyloxy)methyl)furan-2-yl)oxazole-4-carbonitrile chemical structure, C21H21N3O3, CAS 942033-38-7
5-(Piperidin-1-yl)-2-(5-((o-tolyloxy)methyl)furan-2-yl)oxazole-4-carbonitrile
CAS 942033-38-7C21H21N3O3
1-(4-Cyano-2-(5-((o-tolyloxy)methyl)furan-2-yl)oxazol-5-yl)piperidine-4-carboxamide chemical structure, C22H22N4O4, CAS 941904-00-3
1-(4-Cyano-2-(5-((o-tolyloxy)methyl)furan-2-yl)oxazol-5-yl)piperidine-4-carboxamide
CAS 941904-00-3C22H22N4O4
2-{5-[(4-Methylphenoxy)methyl]furan-2-yl}-5-(piperidin-1-yl)-1,3-oxazole-4-carbonitrile chemical structure, C21H21N3O3, CAS 931704-20-0
2-{5-[(4-Methylphenoxy)methyl]furan-2-yl}-5-(piperidin-1-yl)-1,3-oxazole-4-carbonitrile
CAS 931704-20-0C21H21N3O3
1-(4-Cyano-2-{5-[(4-methylphenoxy)methyl]furan-2-yl}-1,3-oxazol-5-yl)piperidine-4-carboxamide chemical structure, C22H22N4O4, CAS 931968-03-5
1-(4-Cyano-2-{5-[(4-methylphenoxy)methyl]furan-2-yl}-1,3-oxazol-5-yl)piperidine-4-carboxamide
CAS 931968-03-5C22H22N4O4
2-{5-[(3-Methylphenoxy)methyl]furan-2-yl}-5-(piperidin-1-yl)-1,3-oxazole-4-carbonitrile chemical structure, C21H21N3O3, CAS 946309-35-9
2-{5-[(3-Methylphenoxy)methyl]furan-2-yl}-5-(piperidin-1-yl)-1,3-oxazole-4-carbonitrile
CAS 946309-35-9C21H21N3O3
5-(3,5-Dimethylpiperidin-1-yl)-2-(5-(phenoxymethyl)furan-2-yl)oxazole-4-carbonitrile chemical structure, C22H23N3O3, CAS 946200-80-2
5-(3,5-Dimethylpiperidin-1-yl)-2-(5-(phenoxymethyl)furan-2-yl)oxazole-4-carbonitrile
CAS 946200-80-2C22H23N3O3
2-{5-[(4-Chlorophenoxy)methyl]furan-2-yl}-5-(3,5-dimethylpiperidin-1-yl)-1,3-oxazole-4-carbonitrile chemical structure, C22H22ClN3O3, CAS 946278-48-4
2-{5-[(4-Chlorophenoxy)methyl]furan-2-yl}-5-(3,5-dimethylpiperidin-1-yl)-1,3-oxazole-4-carbonitrile
CAS 946278-48-4C22H22ClN3O3
5-(3,5-Dimethylpiperidin-1-yl)-2-{5-[(4-methoxyphenoxy)methyl]furan-2-yl}-1,3-oxazole-4-carbonitrile chemical structure, C23H25N3O4, CAS 946278-51-9
5-(3,5-Dimethylpiperidin-1-yl)-2-{5-[(4-methoxyphenoxy)methyl]furan-2-yl}-1,3-oxazole-4-carbonitrile
CAS 946278-51-9C23H25N3O4
5-(3,5-Dimethylpiperidin-1-yl)-2-{5-[(3-methylphenoxy)methyl]furan-2-yl}-1,3-oxazole-4-carbonitrile chemical structure, C23H25N3O3, CAS 946201-04-3
5-(3,5-Dimethylpiperidin-1-yl)-2-{5-[(3-methylphenoxy)methyl]furan-2-yl}-1,3-oxazole-4-carbonitrile
CAS 946201-04-3C23H25N3O3