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Murcko scaffold

Ring system with 4 rings and 25 atoms

145 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
145
With full pages
2
Scaffold SMILES

O=C(Nc1nc(-c2cn(-c3ccccc3)nn2)ns1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1nc(-c2cn(-c3ccccc3)nn2)ns1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 145 chemicals

3,4-Dimethyl-N-{3-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C21H20N6OS, CAS 895112-87-5
3,4-Dimethyl-N-{3-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895112-87-5C21H20N6OS
N-{3-[1-(3-Chloro-4-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-2-methylbenzamide chemical structure, C20H17ClN6OS, CAS 895116-71-9
N-{3-[1-(3-Chloro-4-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-2-methylbenzamide
CAS 895116-71-9C20H17ClN6OS
N-{3-[1-(2,5-Dimethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-3-methoxybenzamide chemical structure, C21H20N6O2S, CAS 895118-15-7
N-{3-[1-(2,5-Dimethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-3-methoxybenzamide
CAS 895118-15-7C21H20N6O2S
N-{3-[1-(3-Chloro-2-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-3-methoxybenzamide chemical structure, C20H17ClN6O2S, CAS 895118-25-9
N-{3-[1-(3-Chloro-2-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-3-methoxybenzamide
CAS 895118-25-9C20H17ClN6O2S
N-{3-[5-Methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C19H16N6OS, CAS 895098-86-9
N-{3-[5-Methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895098-86-9C19H16N6OS
N-{3-[1-(3-Chlorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C18H13ClN6OS, CAS 895098-91-6
N-{3-[1-(3-Chlorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895098-91-6C18H13ClN6OS
N-{3-[1-(2-Fluorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C18H13FN6OS, CAS 895099-01-1
N-{3-[1-(2-Fluorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895099-01-1C18H13FN6OS
N-{3-[1-(3,4-Dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C20H18N6O3S, CAS 895099-36-2
N-{3-[1-(3,4-Dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895099-36-2C20H18N6O3S
N-{3-[1-(3-Chloro-4-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C19H15ClN6OS, CAS 895099-56-6
N-{3-[1-(3-Chloro-4-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895099-56-6C19H15ClN6OS
N-(3-{5-Methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)benzamide chemical structure, C21H20N6OS, CAS 895100-22-8
N-(3-{5-Methyl-1-[4-(propan-2-yl)phenyl]-1H-1,2,3-triazol-4-yl}-1,2,4-thiadiazol-5-yl)benzamide
CAS 895100-22-8C21H20N6OS
4-Chloro-N-{3-[1-(3,4-dimethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C20H17ClN6OS, CAS 895101-07-2
4-Chloro-N-{3-[1-(3,4-dimethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895101-07-2C20H17ClN6OS
4-Chloro-N-{3-[1-(2-ethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C20H17ClN6OS, CAS 895101-42-5
4-Chloro-N-{3-[1-(2-ethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895101-42-5C20H17ClN6OS
3-Chloro-N-{3-[1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C20H17ClN6O3S, CAS 932300-09-9
3-Chloro-N-{3-[1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 932300-09-9C20H17ClN6O3S
4-Methyl-N-[3-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-1,2,4-thiadiazol-5-yl]benzamide chemical structure, C19H16N6OS, CAS 895103-10-3
4-Methyl-N-[3-(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)-1,2,4-thiadiazol-5-yl]benzamide
CAS 895103-10-3C19H16N6OS
N-{3-[1-(3-Chlorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C19H15ClN6OS, CAS 895103-34-1
N-{3-[1-(3-Chlorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895103-34-1C19H15ClN6OS
N-{3-[1-(4-Fluorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C19H15FN6OS, CAS 895103-58-9
N-{3-[1-(4-Fluorophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895103-58-9C19H15FN6OS
N-{3-[1-(4-Bromophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C19H15BrN6OS, CAS 895103-64-7
N-{3-[1-(4-Bromophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895103-64-7C19H15BrN6OS
N-{3-[1-(4-Methoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C20H18N6O2S, CAS 895103-82-9
N-{3-[1-(4-Methoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895103-82-9C20H18N6O2S
N-{3-[1-(3,4-Dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C21H20N6O3S, CAS 895104-00-4
N-{3-[1-(3,4-Dimethoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895104-00-4C21H20N6O3S
N-{3-[1-(5-Chloro-2-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C20H17ClN6OS, CAS 895104-55-9
N-{3-[1-(5-Chloro-2-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895104-55-9C20H17ClN6OS
N-{3-[1-(2-Methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C21H20N6O2S, CAS 895105-09-6
N-{3-[1-(2-Methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895105-09-6C21H20N6O2S
N-{3-[1-(2-Bromophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide chemical structure, C19H15BrN6OS, CAS 895105-21-2
N-{3-[1-(2-Bromophenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}-4-methylbenzamide
CAS 895105-21-2C19H15BrN6OS
4-Bromo-N-{3-[1-(3,4-dimethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C20H17BrN6OS, CAS 895106-17-9
4-Bromo-N-{3-[1-(3,4-dimethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895106-17-9C20H17BrN6OS
4-Bromo-N-{3-[1-(4-ethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide chemical structure, C20H17BrN6OS, CAS 895106-89-5
4-Bromo-N-{3-[1-(4-ethylphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-1,2,4-thiadiazol-5-yl}benzamide
CAS 895106-89-5C20H17BrN6OS