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Murcko scaffold

Ring system with 2 rings and 12 atoms

24 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
24
With full pages
3
Scaffold SMILES

O=c1cc(C2CCNC2)nc[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cc(C2CCNC2)nc[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 24 of 24 chemicals

2-Methyl-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C10H15N3O, CAS 1381031-88-4
2-Methyl-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol
CAS 1381031-88-4C10H15N3O
2-(Dimethylamino)-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C10H16N4O, CAS 1361113-78-1
2-(Dimethylamino)-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 1361113-78-1C10H16N4O
2-Amino-6-(pyrrolidin-3-yl)pyrimidin-4-ol dihydrochloride chemical structure, C8H14Cl2N4O, CAS 1989672-65-2
2-Amino-6-(pyrrolidin-3-yl)pyrimidin-4-ol dihydrochloride
CAS 1989672-65-2C8H14Cl2N4O
2-Amino-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C8H12N4O, CAS 1935384-98-7
2-Amino-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 1935384-98-7C8H12N4O
2-Methyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C9H13N3O, CAS 1858256-81-1
2-Methyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 1858256-81-1C9H13N3O
2-Methyl-6-pyrrolidin-3-ylpyrimidin-4-ol dihydrochloride chemical structure, C9H15Cl2N3O, CAS 2109583-73-3
2-Methyl-6-pyrrolidin-3-ylpyrimidin-4-ol dihydrochloride
CAS 2109583-73-3C9H15Cl2N3O
2-Amino-4-(1-but-2-ynoylpyrrolidin-3-yl)-1H-pyrimidin-6-one chemical structure, C12H14N4O2, CAS 2210051-89-9
2-Amino-4-(1-but-2-ynoylpyrrolidin-3-yl)-1H-pyrimidin-6-one
CAS 2210051-89-9C12H14N4O2
2-(Dimethylamino)-6-(pyrrolidin-3-yl)pyrimidin-4-ol dihydrochloride chemical structure, C10H18Cl2N4O, CAS 2126179-06-2
2-(Dimethylamino)-6-(pyrrolidin-3-yl)pyrimidin-4-ol dihydrochloride
CAS 2126179-06-2C10H18Cl2N4O
2-Amino-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C9H14N4O, CAS 2138157-51-2
2-Amino-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol
CAS 2138157-51-2C9H14N4O
2-(Butan-2-yl)-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C12H19N3O, CAS 2137538-70-4
2-(Butan-2-yl)-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137538-70-4C12H19N3O
2-(Methoxymethyl)-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C10H15N3O2, CAS 2137666-99-8
2-(Methoxymethyl)-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137666-99-8C10H15N3O2
2-Ethyl-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C11H17N3O, CAS 2137667-06-0
2-Ethyl-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137667-06-0C11H17N3O
2-(Dimethylamino)-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C11H18N4O, CAS 2137817-31-1
2-(Dimethylamino)-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137817-31-1C11H18N4O
2-tert-Butyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C12H19N3O, CAS 2138420-44-5
2-tert-Butyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 2138420-44-5C12H19N3O
2-(Propan-2-yl)-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C11H17N3O, CAS 2137516-30-2
2-(Propan-2-yl)-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137516-30-2C11H17N3O
2-Ethyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C10H15N3O, CAS 2137706-69-3
2-Ethyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137706-69-3C10H15N3O
2-Propyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C11H17N3O, CAS 2137835-98-2
2-Propyl-6-(pyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137835-98-2C11H17N3O
6-(1-Methylpyrrolidin-3-yl)-2-propylpyrimidin-4-ol chemical structure, C12H19N3O, CAS 2138132-67-7
6-(1-Methylpyrrolidin-3-yl)-2-propylpyrimidin-4-ol
CAS 2138132-67-7C12H19N3O
2-(Methoxymethyl)-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol chemical structure, C11H17N3O2, CAS 2137836-32-7
2-(Methoxymethyl)-6-(1-methylpyrrolidin-3-yl)pyrimidin-4-ol
CAS 2137836-32-7C11H17N3O2
6-(1-Methylpyrrolidin-3-yl)-2-(propan-2-yl)pyrimidin-4-ol chemical structure, C12H19N3O, CAS 2137516-37-9
6-(1-Methylpyrrolidin-3-yl)-2-(propan-2-yl)pyrimidin-4-ol
CAS 2137516-37-9C12H19N3O
tert-Butyl 3-[2-(dimethylamino)-6-hydroxypyrimidin-4-yl]pyrrolidine-1-carboxylate chemical structure, C15H24N4O3, CAS 2413875-78-0
tert-Butyl 3-[2-(dimethylamino)-6-hydroxypyrimidin-4-yl]pyrrolidine-1-carboxylate
CAS 2413875-78-0C15H24N4O3
tert-Butyl N-[4-hydroxy-6-(1-methylpyrrolidin-3-yl)pyrimidin-2-yl]carbamate chemical structure, C14H22N4O3, CAS 2413875-40-6
tert-Butyl N-[4-hydroxy-6-(1-methylpyrrolidin-3-yl)pyrimidin-2-yl]carbamate
CAS 2413875-40-6C14H22N4O3
6-(Pyrrolidin-3-yl)-2-(trifluoromethyl)pyrimidin-4-ol chemical structure, C9H10F3N3O, CAS 2137666-88-5
6-(Pyrrolidin-3-yl)-2-(trifluoromethyl)pyrimidin-4-ol
CAS 2137666-88-5C9H10F3N3O
tert-Butyl N-[4-hydroxy-6-(pyrrolidin-3-yl)pyrimidin-2-yl]carbamate chemical structure, C13H20N4O3, CAS 2764011-20-1
tert-Butyl N-[4-hydroxy-6-(pyrrolidin-3-yl)pyrimidin-2-yl]carbamate
CAS 2764011-20-1C13H20N4O3