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Murcko scaffold

Ring system with 2 rings and 15 atoms

23 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
15
Chemicals
23
With full pages
7
Scaffold SMILES

O=C(Cc1ccsc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccsc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

N-(4-Bromo-2-fluorophenyl)-2-(thiophen-3-yl)acetamide chemical structure, C12H9BrFNOS, CAS 730987-97-0
N-(4-Bromo-2-fluorophenyl)-2-(thiophen-3-yl)acetamide
CAS 730987-97-0C12H9BrFNOS
N-(3-Chloro-4-methylphenyl)-2-thiophen-3-ylacetamide chemical structure, C13H12ClNOS, CAS 731804-03-8
N-(3-Chloro-4-methylphenyl)-2-thiophen-3-ylacetamide
CAS 731804-03-8C13H12ClNOS
N-(4-Iodophenyl)-2-(thiophen-3-yl)acetamide chemical structure, C12H10INOS, CAS 733795-97-6
N-(4-Iodophenyl)-2-(thiophen-3-yl)acetamide
CAS 733795-97-6C12H10INOS
N-(4-Bromo-3-methylphenyl)-2-(thiophen-3-yl)acetamide chemical structure, C13H12BrNOS, CAS 727716-78-1
N-(4-Bromo-3-methylphenyl)-2-(thiophen-3-yl)acetamide
CAS 727716-78-1C13H12BrNOS
N-(2-Ethyl-6-methylphenyl)-2-thiophen-3-ylacetamide chemical structure, C15H17NOS, CAS 851790-26-6
N-(2-Ethyl-6-methylphenyl)-2-thiophen-3-ylacetamide
CAS 851790-26-6C15H17NOS
N-(2-Bromo-4-methylphenyl)-2-(thiophen-3-yl)acetamide chemical structure, C13H12BrNOS, CAS 850601-61-5
N-(2-Bromo-4-methylphenyl)-2-(thiophen-3-yl)acetamide
CAS 850601-61-5C13H12BrNOS
N-(4-Chlorophenyl)-2-(thiophen-3-yl)acetamide chemical structure, C12H10ClNOS, CAS 849602-07-9
N-(4-Chlorophenyl)-2-(thiophen-3-yl)acetamide
CAS 849602-07-9C12H10ClNOS
N-(5-Fluoro-2-methylphenyl)-2-thiophen-3-ylacetamide chemical structure, C13H12FNOS, CAS 850592-85-7
N-(5-Fluoro-2-methylphenyl)-2-thiophen-3-ylacetamide
CAS 850592-85-7C13H12FNOS
N-(4,5-Dimethoxy-2-methylphenyl)-2-thiophen-3-ylacetamide chemical structure, C15H17NO3S, CAS 875525-24-9
N-(4,5-Dimethoxy-2-methylphenyl)-2-thiophen-3-ylacetamide
CAS 875525-24-9C15H17NO3S
N-(3-Acetylphenyl)-2-(thiophen-3-yl)acetamide chemical structure, C14H13NO2S, CAS 903800-23-7
N-(3-Acetylphenyl)-2-(thiophen-3-yl)acetamide
CAS 903800-23-7C14H13NO2S
N-(4-Chloro-2-fluorophenyl)-2-(thiophen-3-yl)acetamide chemical structure, C12H9ClFNOS, CAS 1004075-19-7
N-(4-Chloro-2-fluorophenyl)-2-(thiophen-3-yl)acetamide
CAS 1004075-19-7C12H9ClFNOS
Benzoic acid, 2-[(3-thienylacetyl)amino]-, methyl ester chemical structure, C14H13NO3S, CAS 89080-90-0
Benzoic acid, 2-[(3-thienylacetyl)amino]-, methyl ester
CAS 89080-90-0C14H13NO3S
N-[2-(Diethylamino)ethyl]-4-[2-(thiophen-3-yl)acetamido]benzamide chemical structure, C19H25N3O2S, CAS 877953-41-8
N-[2-(Diethylamino)ethyl]-4-[2-(thiophen-3-yl)acetamido]benzamide
CAS 877953-41-8C19H25N3O2S
Ethyl 2-hydroxy-5-[2-(thiophen-3-yl)acetamido]benzoate chemical structure, C15H15NO4S, CAS 90056-03-4
Ethyl 2-hydroxy-5-[2-(thiophen-3-yl)acetamido]benzoate
CAS 90056-03-4C15H15NO4S
N-(2-Acetylphenyl)-2-(thiophen-3-yl)acetamide chemical structure, C14H13NO2S, CAS 89080-87-5
N-(2-Acetylphenyl)-2-(thiophen-3-yl)acetamide
CAS 89080-87-5C14H13NO2S
4-[2-(Thiophen-3-yl)acetamido]benzamide chemical structure, C13H12N2O2S, CAS 940765-92-4
4-[2-(Thiophen-3-yl)acetamido]benzamide
CAS 940765-92-4C13H12N2O2S
N-(2,4-Dichlorophenyl)-2-(thiophen-3-yl)acetamide chemical structure, C12H9Cl2NOS, CAS 1007718-01-5
N-(2,4-Dichlorophenyl)-2-(thiophen-3-yl)acetamide
CAS 1007718-01-5C12H9Cl2NOS
3-[2-(Thiophen-3-yl)acetamido]benzoic acid chemical structure, C13H11NO3S, CAS 206983-07-5
3-[2-(Thiophen-3-yl)acetamido]benzoic acid
CAS 206983-07-5C13H11NO3S
N-(2-Bromo-4-fluorophenyl)-2-(thiophen-3-yl)acetamide chemical structure, C12H9BrFNOS, CAS 1038737-49-3
N-(2-Bromo-4-fluorophenyl)-2-(thiophen-3-yl)acetamide
CAS 1038737-49-3C12H9BrFNOS
N-(3-(Hydroxymethyl)phenyl)-2-(thiophen-3-yl)acetamide chemical structure, C13H13NO2S, CAS 1183874-84-1
N-(3-(Hydroxymethyl)phenyl)-2-(thiophen-3-yl)acetamide
CAS 1183874-84-1C13H13NO2S
3-[2-(4-Chloroanilino)-2-oxoethyl]thiophene-2-carboxylic acid chemical structure, C13H10ClNO3S, CAS 917614-43-8
3-[2-(4-Chloroanilino)-2-oxoethyl]thiophene-2-carboxylic acid
CAS 917614-43-8C13H10ClNO3S
N-(4-(2-Oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)phenyl)-2-(thiophen-3-yl)acetamide chemical structure, C16H15F3N2O2S, CAS 1448072-59-0
N-(4-(2-Oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)phenyl)-2-(thiophen-3-yl)acetamide
CAS 1448072-59-0C16H15F3N2O2S
N-(4-Chloro-3-((3-methylbut-2-EN-1-yl)oxy)phenyl)-2-(2-methylthiophen-3-yl)acetamide chemical structure, C18H20ClNO2S, CAS 2135331-94-9
N-(4-Chloro-3-((3-methylbut-2-EN-1-yl)oxy)phenyl)-2-(2-methylthiophen-3-yl)acetamide
CAS 2135331-94-9C18H20ClNO2S