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Murcko scaffold

1-(Pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline scaffold

9 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 16
Chemicals: 9
With full pages: 3

Scaffold SMILES

c1ccc2c(c1)CCNC2c1ccncc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 1-(Pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline page

Murcko scaffold c1ccc2c(c1)CCNC2c1ccncc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-(2-Methyl-3-hydroxy-5-hydroxymethyl-4-pyridyl)-6,7-dihydroxy-1,2-3,4-tetrahydroisoquinoline chemical structure, C16H18N2O4, CAS 36120-58-8

1-(2-Methyl-3-hydroxy-5-hydroxymethyl-4-pyridyl)-6,7-dihydroxy-1,2-3,4-tetrahydroisoquinoline

CAS 36120-58-8C₁₆H₁₈N₂O₄

3-(1-Pyridin-4-yl-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid chemical structure, C17H18N2O2, CAS 610258-80-5

3-(1-Pyridin-4-yl-3,4-dihydroisoquinolin-2(1H)-yl)propanoic acid

CAS 610258-80-5C₁₇H₁₈N₂O₂

1-(Pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C14H14N2, CAS 180272-43-9

1-(Pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline

CAS 180272-43-9C₁₄H₁₄N₂

6,7-Dimethoxy-1-(pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C16H18N2O2, CAS 3161-05-5

6,7-Dimethoxy-1-(pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline

CAS 3161-05-5C₁₆H₁₈N₂O₂

1-Pyridin-4-yl-1,2,3,4-tetrahydroisoquinolin-6-ol chemical structure, C14H14N2O, CAS 600647-50-5

1-Pyridin-4-yl-1,2,3,4-tetrahydroisoquinolin-6-ol

CAS 600647-50-5C₁₄H₁₄N₂O

1-(3-Methylpyridin-4-yl)-1,2,3,4-tetrahydroisoquinolin-6-ol chemical structure, C15H16N2O, CAS 600647-67-4

1-(3-Methylpyridin-4-yl)-1,2,3,4-tetrahydroisoquinolin-6-ol

CAS 600647-67-4C₁₅H₁₆N₂O

6-Methoxy-1-(pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline chemical structure, C15H16N2O, CAS 600647-43-6

6-Methoxy-1-(pyridin-4-yl)-1,2,3,4-tetrahydroisoquinoline

CAS 600647-43-6C₁₅H₁₆N₂O

6,7-Dimethoxy-1-(4-pyridyl)-1,2,3,4-tetrahydro-isoquinoline dihydrochloride chemical structure, C16H20Cl2N2O2, CAS 298196-89-1

6,7-Dimethoxy-1-(4-pyridyl)-1,2,3,4-tetrahydro-isoquinoline dihydrochloride

CAS 298196-89-1C₁₆H₂₀Cl₂N₂O₂

1,2,3,4-Tetrahydro-4,4-dimethyl-1-(4-pyridinyl)isoquinoline chemical structure, C16H18N2, CAS 1159011-00-3

1,2,3,4-Tetrahydro-4,4-dimethyl-1-(4-pyridinyl)isoquinoline

CAS 1159011-00-3C₁₆H₁₈N₂