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Murcko scaffold

Ring system with 3 rings and 16 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
14
With full pages
3
Scaffold SMILES

O=c1cnnc2sc(-c3ccccc3)nn12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cnnc2sc(-c3ccccc3)nn12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

7-(3-Chlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H7ClN4OS, CAS 59758-58-6
7-(3-Chlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 59758-58-6C11H7ClN4OS
7-[4-(Dimethylamino)phenyl]-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C13H13N5OS, CAS 892675-62-6
7-[4-(Dimethylamino)phenyl]-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 892675-62-6C13H13N5OS
7-(4-Methoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C12H10N4O2S, CAS 43029-26-1
7-(4-Methoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 43029-26-1C12H10N4O2S
7-(3-Fluorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H7FN4OS, CAS 903190-41-0
7-(3-Fluorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 903190-41-0C11H7FN4OS
3-Methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H8N4OS, CAS 43098-57-3
3-Methyl-7-phenyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 43098-57-3C11H8N4OS
7-(3-Bromophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H7BrN4OS, CAS 919738-68-4
7-(3-Bromophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 919738-68-4C11H7BrN4OS
7-(4-Chlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H7ClN4OS, CAS 43029-28-3
7-(4-Chlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 43029-28-3C11H7ClN4OS
7-(2,4-Dichlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H6Cl2N4OS, CAS 892689-12-2
7-(2,4-Dichlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 892689-12-2C11H6Cl2N4OS
7-(3,4-Dichlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C11H6Cl2N4OS, CAS 892689-16-6
7-(3,4-Dichlorophenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 892689-16-6C11H6Cl2N4OS
7-(3-Methoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C12H10N4O2S, CAS 59758-59-7
7-(3-Methoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 59758-59-7C12H10N4O2S
7-(3,4-Dimethoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C13H12N4O3S, CAS 914356-67-5
7-(3,4-Dimethoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 914356-67-5C13H12N4O3S
3-Methyl-7-(3,4,5-trimethoxyphenyl)-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C14H14N4O4S, CAS 919011-26-0
3-Methyl-7-(3,4,5-trimethoxyphenyl)-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 919011-26-0C14H14N4O4S
7-(4-Ethoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C13H12N4O2S, CAS 1003980-39-9
7-(4-Ethoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 1003980-39-9C13H12N4O2S
7-(4-Ethoxy-3-methoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one chemical structure, C14H14N4O3S, CAS 892690-01-6
7-(4-Ethoxy-3-methoxyphenyl)-3-methyl-4H-[1,3,4]thiadiazolo[2,3-c][1,2,4]triazin-4-one
CAS 892690-01-6C14H14N4O3S