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Murcko scaffold

Ring system with 3 rings and 21 atoms

37 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
37
With full pages
8
Scaffold SMILES

O=C(Nc1ccccc1N1CCCCC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1N1CCCCC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 37 of 37 chemicals

3-Fluoro-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C18H19FN2O, CAS 532980-51-1
3-Fluoro-N-(2-piperidin-1-ylphenyl)benzamide
CAS 532980-51-1C18H19FN2O
4-Fluoro-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C18H19FN2O, CAS 530131-99-8
4-Fluoro-N-(2-piperidin-1-ylphenyl)benzamide
CAS 530131-99-8C18H19FN2O
N-(3-Chloro-2-piperidin-1-ylphenyl)-4-fluorobenzamide chemical structure, C18H18ClFN2O, CAS 718602-32-5
N-(3-Chloro-2-piperidin-1-ylphenyl)-4-fluorobenzamide
CAS 718602-32-5C18H18ClFN2O
4-Cyano-2-fluoro-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide chemical structure, C20H20FN3O, CAS 701254-57-1
4-Cyano-2-fluoro-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide
CAS 701254-57-1C20H20FN3O
2-Methoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide chemical structure, C20H24N2O2, CAS 892682-98-3
2-Methoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide
CAS 892682-98-3C20H24N2O2
3-Nitro-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C18H19N3O3, CAS 443895-82-7
3-Nitro-N-(2-piperidin-1-ylphenyl)benzamide
CAS 443895-82-7C18H19N3O3
2-Chloro-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C18H19ClN2O, CAS 443294-63-1
2-Chloro-N-(2-piperidin-1-ylphenyl)benzamide
CAS 443294-63-1C18H19ClN2O
2-Fluoro-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C18H19FN2O, CAS 531544-18-0
2-Fluoro-N-(2-piperidin-1-ylphenyl)benzamide
CAS 531544-18-0C18H19FN2O
2-Bromo-N-(3-chloro-2-piperidin-1-ylphenyl)benzamide chemical structure, C18H18BrClN2O, CAS 712290-85-2
2-Bromo-N-(3-chloro-2-piperidin-1-ylphenyl)benzamide
CAS 712290-85-2C18H18BrClN2O
2-Methoxy-N-[2-piperidin-1-yl-5-(trifluoromethyl)phenyl]benzamide chemical structure, C20H21F3N2O2, CAS 672321-13-0
2-Methoxy-N-[2-piperidin-1-yl-5-(trifluoromethyl)phenyl]benzamide
CAS 672321-13-0C20H21F3N2O2
2,6-Dimethoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide chemical structure, C21H26N2O3, CAS 701247-91-8
2,6-Dimethoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide
CAS 701247-91-8C21H26N2O3
4-Methoxy-3-nitro-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C19H21N3O4, CAS 531545-71-8
4-Methoxy-3-nitro-N-(2-piperidin-1-ylphenyl)benzamide
CAS 531545-71-8C19H21N3O4
N-(3-Chloro-2-piperidinophenyl)-3-nitrobenzenecarboxamide chemical structure, C18H18ClN3O3, CAS 383145-58-2
N-(3-Chloro-2-piperidinophenyl)-3-nitrobenzenecarboxamide
CAS 383145-58-2C18H18ClN3O3
N-(5-Chloro-2-piperidinophenyl)-4-fluorobenzenecarboxamide chemical structure, C18H18ClFN2O, CAS 847839-63-8
N-(5-Chloro-2-piperidinophenyl)-4-fluorobenzenecarboxamide
CAS 847839-63-8C18H18ClFN2O
N-(5-Chloro-2-piperidin-1-ylphenyl)-3-methylbenzamide chemical structure, C19H21ClN2O, CAS 383146-53-0
N-(5-Chloro-2-piperidin-1-ylphenyl)-3-methylbenzamide
CAS 383146-53-0C19H21ClN2O
N-(5-Chloro-2-piperidinophenyl)-4-methylbenzenecarboxamide chemical structure, C19H21ClN2O, CAS 383146-55-2
N-(5-Chloro-2-piperidinophenyl)-4-methylbenzenecarboxamide
CAS 383146-55-2C19H21ClN2O
2-Fluoro-N-[2-piperidin-1-yl-5-(trifluoromethyl)phenyl]benzamide chemical structure, C19H18F4N2O, CAS 688033-17-2
2-Fluoro-N-[2-piperidin-1-yl-5-(trifluoromethyl)phenyl]benzamide
CAS 688033-17-2C19H18F4N2O
3,4,5-Triethoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide chemical structure, C25H34N2O4, CAS 701258-50-6
3,4,5-Triethoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide
CAS 701258-50-6C25H34N2O4
5-Bromo-2-methoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide chemical structure, C20H23BrN2O2, CAS 701258-65-3
5-Bromo-2-methoxy-N-[2-(4-methylpiperidin-1-yl)phenyl]benzamide
CAS 701258-65-3C20H23BrN2O2
N-(3-Chloro-2-piperidin-1-ylphenyl)-2-iodobenzamide chemical structure, C18H18ClIN2O, CAS 823823-96-7
N-(3-Chloro-2-piperidin-1-ylphenyl)-2-iodobenzamide
CAS 823823-96-7C18H18ClIN2O
2-Methyl-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C19H22N2O, CAS 532942-44-2
2-Methyl-N-(2-piperidin-1-ylphenyl)benzamide
CAS 532942-44-2C19H22N2O
4-(Difluoromethoxy)-N-(2-piperidin-1-ylphenyl)benzamide chemical structure, C19H20F2N2O2, CAS 568575-05-3
4-(Difluoromethoxy)-N-(2-piperidin-1-ylphenyl)benzamide
CAS 568575-05-3C19H20F2N2O2
N-(5-Chloro-2-piperidin-1-ylphenyl)-3,4,5-trimethoxybenzamide chemical structure, C21H25ClN2O4, CAS 852294-38-3
N-(5-Chloro-2-piperidin-1-ylphenyl)-3,4,5-trimethoxybenzamide
CAS 852294-38-3C21H25ClN2O4
4-Chloro-N-(3-chloro-2-piperidinophenyl)benzenecarboxamide chemical structure, C18H18Cl2N2O, CAS 860610-28-2
4-Chloro-N-(3-chloro-2-piperidinophenyl)benzenecarboxamide
CAS 860610-28-2C18H18Cl2N2O