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Murcko scaffold

2,3-Dihydrofuran scaffold

250 chemicals on CompoundList share this ring system.

Rings
1
Scaffold atoms
5
Chemicals
250
With full pages
18
Scaffold SMILES

C1=COCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks. This is a very common single ring, so the list below is broad.

Substructure search with this scaffoldOpen the 2,3-Dihydrofuran page
Murcko scaffold C1=COCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 250 chemicals

2,3-Dihydro-5-methylfuran chemical structure, C5H8O, CAS 1487-15-6
2,3-Dihydro-5-methylfuran
CAS 1487-15-6C5H8O
2,3-Dihydro-4-methylfuran chemical structure, C5H8O, CAS 34314-83-5
2,3-Dihydro-4-methylfuran
CAS 34314-83-5C5H8O
2,3-Dihydro-4-(1-methylethyl)furan chemical structure, C7H12O, CAS 34314-84-6
2,3-Dihydro-4-(1-methylethyl)furan
CAS 34314-84-6C7H12O
2,3-Dihydrofuran chemical structure, C4H6O, CAS 1191-99-7
2,3-Dihydrofuran
CAS 1191-99-7C4H6O
3-Furancarboxylic acid, 4,5-dihydro-2-methyl-5-propyl-, ethyl ester chemical structure, C11H18O3, CAS 109176-12-7
3-Furancarboxylic acid, 4,5-dihydro-2-methyl-5-propyl-, ethyl ester
CAS 109176-12-7C11H18O3
2,5-Dimethyl-2,3-dihydrofuran chemical structure, C6H10O, CAS 17108-52-0
2,5-Dimethyl-2,3-dihydrofuran
CAS 17108-52-0C6H10O
2,3-Dihydro-3-methylfuran chemical structure, C5H8O, CAS 1708-27-6
2,3-Dihydro-3-methylfuran
CAS 1708-27-6C5H8O
3-Furancarboxylic acid, 5-ethyl-4,5-dihydro-2-methyl-, ethyl ester chemical structure, C10H16O3, CAS 97953-23-6
3-Furancarboxylic acid, 5-ethyl-4,5-dihydro-2-methyl-, ethyl ester
CAS 97953-23-6C10H16O3
Ethyl 2-amino-4,5-dihydro-3-furoate chemical structure, C7H11NO3, CAS 29108-09-6
Ethyl 2-amino-4,5-dihydro-3-furoate
CAS 29108-09-6C7H11NO3
Ribal chemical structure, C5H8O3, CAS 96761-00-1
Ribal
CAS 96761-00-1C5H8O3
2,3,3,5-Tetramethyl-2-(2-methylprop-1-en-1-yl)-2,3-dihydrofuran chemical structure, C12H20O, CAS 706-87-6
2,3,3,5-Tetramethyl-2-(2-methylprop-1-en-1-yl)-2,3-dihydrofuran
CAS 706-87-6C12H20O
1,6-Diethyl 2,5-anhydro-3-deoxy-3-(ethoxycarbonyl)-4-c-(ethoxycarbonyl)hex-2-enarate chemical structure, C16H22O10, CAS 6307-27-3
1,6-Diethyl 2,5-anhydro-3-deoxy-3-(ethoxycarbonyl)-4-c-(ethoxycarbonyl)hex-2-enarate
CAS 6307-27-3C16H22O10
4,5-Dimethyl-2,3-dihydrofuran chemical structure, C6H10O, CAS 1487-16-7
4,5-Dimethyl-2,3-dihydrofuran
CAS 1487-16-7C6H10O
Antibiotic A121 chemical structure, C18H30O5, CAS 68072-84-4
Antibiotic A121
CAS 68072-84-4C18H30O5
Furan, 5-ethyl-2,3-dihydro- chemical structure, C6H10O, CAS 38614-09-4
Furan, 5-ethyl-2,3-dihydro-
CAS 38614-09-4C6H10O
4,5-Dihydro-2-methyl-3-furanthiol chemical structure, C5H8OS, CAS 26486-13-5
4,5-Dihydro-2-methyl-3-furanthiol
CAS 26486-13-5C5H8OS
3-tert-Butyl-2,3-dihydrofuran chemical structure, C8H14O, CAS 34314-82-4
3-tert-Butyl-2,3-dihydrofuran
CAS 34314-82-4C8H14O
3-Butan-2-yl-2,3-dihydrofuran chemical structure, C8H14O, CAS 56805-32-4
3-Butan-2-yl-2,3-dihydrofuran
CAS 56805-32-4C8H14O
4-sec-Butyl-2,3-dihydrofuran chemical structure, C8H14O, CAS 34379-54-9
4-sec-Butyl-2,3-dihydrofuran
CAS 34379-54-9C8H14O
4,5-Dihydrofuran-3-carboxylic acid chemical structure, C5H6O3, CAS 98021-62-6
4,5-Dihydrofuran-3-carboxylic acid
CAS 98021-62-6C5H6O3
2,2,2-Trichloro-1-(4,5-dihydrofuran-3-yl)ethanone chemical structure, C6H5Cl3O2, CAS 83124-80-5
2,2,2-Trichloro-1-(4,5-dihydrofuran-3-yl)ethanone
CAS 83124-80-5C6H5Cl3O2
1-(4,5-Dihydrofuran-3-yl)-2,2,2-trifluoroethan-1-one chemical structure, C6H5F3O2, CAS 109317-75-1
1-(4,5-Dihydrofuran-3-yl)-2,2,2-trifluoroethan-1-one
CAS 109317-75-1C6H5F3O2
Ethyl 4,5-dihydro-5-methoxy-2,4-dimethyl-3-furancarboxylate chemical structure, C10H16O4, CAS 124186-12-5
Ethyl 4,5-dihydro-5-methoxy-2,4-dimethyl-3-furancarboxylate
CAS 124186-12-5C10H16O4
3-Furanmethanol, 4,5-dihydro-2,4-dimethyl-5-methoxy- chemical structure, C8H14O3, CAS 124186-13-6
3-Furanmethanol, 4,5-dihydro-2,4-dimethyl-5-methoxy-
CAS 124186-13-6C8H14O3