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Murcko scaffold

Ring system with 3 rings and 21 atoms

15 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
15
With full pages
2
Scaffold SMILES

c1ccc(COc2cccc(Sc3ccccc3)c2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(COc2cccc(Sc3ccccc3)c2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 15 of 15 chemicals

4-Nitro-3-[4-nitro-3-(phenylmethoxy)phenylthio]benzoic acid chemical structure, C20H14N2O7S, CAS 313498-79-2
4-Nitro-3-[4-nitro-3-(phenylmethoxy)phenylthio]benzoic acid
CAS 313498-79-2C20H14N2O7S
4-Benzyloxy-2-(2'-carbomethoxy)thiophenylnitrobenzene chemical structure, C21H17NO5S, CAS 329217-03-0
4-Benzyloxy-2-(2'-carbomethoxy)thiophenylnitrobenzene
CAS 329217-03-0C21H17NO5S
Methyl 2-{[2-amino-5-(benzyloxy)phenyl]sulfanyl}benzoate chemical structure, C21H19NO3S, CAS 329217-05-2
Methyl 2-{[2-amino-5-(benzyloxy)phenyl]sulfanyl}benzoate
CAS 329217-05-2C21H19NO3S
1,3-Propanediol, 2-amino-2-(2-(2-chloro-4-((3-(phenylmethoxy)phenyl)thio)phenyl)ethyl)-, hydrochloride (1:1) chemical structure, C24H27Cl2NO3S, CAS 509088-69-1
1,3-Propanediol, 2-amino-2-(2-(2-chloro-4-((3-(phenylmethoxy)phenyl)thio)phenyl)ethyl)-, hydrochloride (1:1)
CAS 509088-69-1C24H27Cl2NO3S
Mocravimod chemical structure, C24H26ClNO3S, CAS 509092-16-4
Mocravimod
CAS 509092-16-4C24H26ClNO3S
2-[2-[4-(3-Benzyloxyphenylthio)-2-chlorophenyl]ethyl]-2-nitro-1,3-propanediol chemical structure, C24H24ClNO5S, CAS 883718-65-8
2-[2-[4-(3-Benzyloxyphenylthio)-2-chlorophenyl]ethyl]-2-nitro-1,3-propanediol
CAS 883718-65-8C24H24ClNO5S
[2-Amino-4-[2-chloro-4-(3-phenylmethoxyphenyl)sulfanylphenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate chemical structure, C24H27ClNO6PS, CAS 749262-82-6
[2-Amino-4-[2-chloro-4-(3-phenylmethoxyphenyl)sulfanylphenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
CAS 749262-82-6C24H27ClNO6PS
4-(3-Benzyloxyphenylthio)-2-chlorobenzaldehyde chemical structure, C20H15ClO2S, CAS 883718-60-3
4-(3-Benzyloxyphenylthio)-2-chlorobenzaldehyde
CAS 883718-60-3C20H15ClO2S
Benzene, 1-[[3-chloro-4-(2-iodoethyl)phenyl]thio]-3-(phenylmethoxy)- chemical structure, C21H18ClIOS, CAS 509089-05-8
Benzene, 1-[[3-chloro-4-(2-iodoethyl)phenyl]thio]-3-(phenylmethoxy)-
CAS 509089-05-8C21H18ClIOS
Ethyl 2-(4-((3-(benzyloxy)phenyl)thio)-2-chlorophenyl)acetate chemical structure, C23H21ClO3S, CAS 509089-12-7
Ethyl 2-(4-((3-(benzyloxy)phenyl)thio)-2-chlorophenyl)acetate
CAS 509089-12-7C23H21ClO3S
2-{2-[4-(3-Benzyloxy-phenylsulfanyl)-2-chloro-phenyl]-ethyl}-2-fluoro-malonic acid diethyl ester chemical structure, C28H28ClFO5S, CAS 1023648-24-9
2-{2-[4-(3-Benzyloxy-phenylsulfanyl)-2-chloro-phenyl]-ethyl}-2-fluoro-malonic acid diethyl ester
CAS 1023648-24-9C28H28ClFO5S
Dimethyl [2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl](methoxy)propanedioate chemical structure, C27H27ClO6S, CAS 1023648-23-8
Dimethyl [2-(4-{[3-(benzyloxy)phenyl]sulfanyl}-2-chlorophenyl)ethyl](methoxy)propanedioate
CAS 1023648-23-8C27H27ClO6S
Carbamic acid, N-[3-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]-1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester chemical structure, C29H34ClNO5S, CAS 509088-47-5
Carbamic acid, N-[3-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]-1,1-bis(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester
CAS 509088-47-5C29H34ClNO5S
N-Acetyl-di-O-acetyl KRP-203 chemical structure, C30H32ClNO6S, CAS 951238-25-8
N-Acetyl-di-O-acetyl KRP-203
CAS 951238-25-8C30H32ClNO6S
Propanedioic acid, 2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,3-diethyl ester chemical structure, C33H38ClNO7S, CAS 509088-30-6
Propanedioic acid, 2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-2-[[(1,1-dimethylethoxy)carbonyl]amino]-, 1,3-diethyl ester
CAS 509088-30-6C33H38ClNO7S